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Med Cutan Ibero Lat Am ; 16(5): 397-401, 1988.
Artigo em Espanhol | MEDLINE | ID: mdl-3070196

RESUMO

T cells and the theophylline resistant cells (the-r, helper cells) in peripheral blood of patients with different forms of leprosy were studied. Active lepromatous patients (LL+) showed a significant decrease in T lymphocytes and the-r cells. Nevertheless, in LL+ developing a reactional episode of erythema nodosum (LL-ENL) a restoration in the level of the-r cells was observed. It is concluded that in LL+ patients the depression of T cells and the-r cells represents an imbalance in the T-T cellular cooperation with a defective cellular immune response. On the other hand, the recovery of the-r cells in LL-ENL support the hypothesis of a cell mediated immune mechanism in the immunopathology of this reactional episode.


Assuntos
Hanseníase/imunologia , Linfócitos T/classificação , Teofilina , Humanos , Imunidade Celular , Pessoa de Meia-Idade , Linfócitos T/fisiopatologia
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