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[Study of T lymphocyte subpopulations in patients with leprosy, using incubation with theophylline]. / Estudio de subpoblaciones de linfocitos T en pacientes con lepra, mediante la incubación con teofilina.
Bottasso, O; Puig, N; Amerio, N; Morini, J C.
Afiliação
  • Bottasso O; División Inmunología, Facultad de Ciencias Médicas, Universidad Nacional de Rosario, Argentina.
Med Cutan Ibero Lat Am ; 16(5): 397-401, 1988.
Article em Es | MEDLINE | ID: mdl-3070196
T cells and the theophylline resistant cells (the-r, helper cells) in peripheral blood of patients with different forms of leprosy were studied. Active lepromatous patients (LL+) showed a significant decrease in T lymphocytes and the-r cells. Nevertheless, in LL+ developing a reactional episode of erythema nodosum (LL-ENL) a restoration in the level of the-r cells was observed. It is concluded that in LL+ patients the depression of T cells and the-r cells represents an imbalance in the T-T cellular cooperation with a defective cellular immune response. On the other hand, the recovery of the-r cells in LL-ENL support the hypothesis of a cell mediated immune mechanism in the immunopathology of this reactional episode.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Teofilina / Linfócitos T / Hanseníase Limite: Humans / Middle aged Idioma: Es Revista: Med Cutan Ibero Lat Am Ano de publicação: 1988 Tipo de documento: Article País de afiliação: Argentina País de publicação: Portugal
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Teofilina / Linfócitos T / Hanseníase Limite: Humans / Middle aged Idioma: Es Revista: Med Cutan Ibero Lat Am Ano de publicação: 1988 Tipo de documento: Article País de afiliação: Argentina País de publicação: Portugal