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1.
Data Brief ; 54: 110480, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38725554

RESUMO

Roselle (Hibiscus sabdariffa L.) is a worldwide known species of great importance due to its medicinal properties and pleasant flavor. In Paraguay, it is used as an alternative crop by family-run farmers; however, the varieties used in the country are unknown, so no information is available on this crop. The qualitative characterization would collect knowledge serving as a basis for the registration of varieties produced in Paraguay. In addition, such data are useful for future genetic improvement programs considering this crop. The present work was carried out at the Multidisciplinary Center for Technological Research and the experimental farmland of the Faculty of Agricultural Sciences of the National University of Asuncion, during the years 2022 and 2023. The main objective was to carry out a morphological characterization of four Roselle varieties: Ana Delia, Benito, Dogo, and Creole. The design consisted of completely randomized blocks, with four treatments (varieties) and four replications; each experimental unit (block) was composed of 24 plants, distributed in four rows; 12 plants, selected from the central rows, were harvested for the evaluations. Stem color, leaf shape, leaf margin, rib color, petiole color, flower color, calyx color, calyx sepal opening, capsule shape, capsule color, capsule anthocyanin coloration, and pubescence level were evaluated. The results demonstrate qualitative differences between the varieties, which help to compare and classify them for a better variety selection.

2.
Nat Prod Res ; : 1-10, 2023 Aug 10.
Artigo em Inglês | MEDLINE | ID: mdl-37585694

RESUMO

Due to the high content of phenolics and anthocyanins of Hibiscus sabdariffa L. tea and the sensibility of these bioactive compounds, this work aimed to optimize the obtention of microcapsules by spray-drying, using inulin as a carrier agent. Using a Box-Behnken Design, the effects of inlet temperature (130, 150, and 170 °C), feed flow rate (5, 10, and 15 mL min-1), and inulin concentration (5, 10, and 15 g L-1) were evaluated. It was possible to obtain pale-rose, slightly sweet instant powders with good total polyphenol content (1.12 mgGAE g-1) and anthocyanins encapsulation efficiency (32.3-60.6%), besides moisture (4.61-17.79%) and water activity (0.221-0.501), indicating physico-chemical and microbiological stability of the microcapsules. A simultaneous optimization with the desirability function was performed to maximize all the response variables analyzed, and the optimum conditions of 5 g L-1 of inulin, inlet temperature of 170 °C, and feed flow rate of 83 mL min-1 were found.

3.
Plant Foods Hum Nutr ; 78(2): 342-350, 2023 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-37120677

RESUMO

Hibiscus sabdariffa L. is a worldwide component for tea and beverages, being a natural source of anthocyanins, which are associated with cardiovascular activities. To investigate this relationship, we explored different methods of aqueous extraction on the anthocyanin content and antioxidant activity of H. sabdariffa L. calyx extract (HSCE). Pharmacological effects via platelet aggregation, calcium mobilization, cyclic nucleotide levels, vasodilator-stimulated phosphoprotein Ser157 and Ser239, and on the vasomotor response of aortic rings isolated from mice are studied herewith. We found that the application of ultrasonic turbolization, 20 min, combined with acidified water was significantly more effective in the extraction process, providing extracts with the highest levels of anthocyanins (8.73 and 9.63 mg/100 g) and higher antioxidant activity (6.66 and 6.78 µM trolox/g of sample). HSCE significantly inhibited (100-1000 µg/mL) arachidonic acid-induced platelet aggregation, reduced calcium mobilization, and increased cAMP and cGMP levels with VASPSer157 and VASPSer239 phosphorylation. Vasorelaxation reduction was confirmed by the aortic rings and endothelium assays treated with nitric oxide synthase inhibitors, soluble guanylyl cyclase (sGC) oxidizing agent, or Ca2+-activated K+ channel inhibitor. The increasing of cGMP levels could be understood considering the sGC stimulation by HSCE compounds in the specific stimulus domain, which allows an understanding of the observed antiplatelet and vasorelaxant properties of H. sabdariffa L. calyx extract.


Assuntos
Hibiscus , Vasodilatadores , Animais , Camundongos , Vasodilatadores/farmacologia , Antocianinas/farmacologia , Antioxidantes/farmacologia , Cálcio , Extratos Vegetais/farmacologia , GMP Cíclico/metabolismo
4.
Foods ; 10(6)2021 May 25.
Artigo em Inglês | MEDLINE | ID: mdl-34070238

RESUMO

Heterocyclic amines (HCAs) are compounds with carcinogenic potential formed during high-temperature processing of meat and meat products. Vegetables or their extracts with high antioxidant capacity can be incorporated into the meat matrix to reduce their formation, but it is necessary to find the optimal levels to achieve maximum inhibition without affecting the sensory properties. The objective of this study was to evaluate the effects of roselle extract (RE, 0-1%), potato peel flour (PP, 0-2%), and beef fat (BF, 0-15%) on the sensory properties and formation of HCAs in beef patties using response surface methodology. IQx, IQ, MeIQx, MeIQ, 4,8-DiMeIQx, and PhIP were identified and quantified by HPLC. Regression models were developed to predict sensory properties and HCAs' formation. All models were significant (p < 0.05) and showed a R2 > 0.70. Roselle extract and beef fat had a negative linear effect on the formation of the total HCAs, while PP had a positive linear effect. The optimal formula that minimizes the formation of HCAs included 0.63% RE, 0.99% PP, and 11.96% BF. RE and PP are foods that can be used as ingredients in low-fat beef patties to minimize the formation of HCAs without affecting their sensory properties.

5.
J Med Food ; 24(1): 67-76, 2021 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-32326807

RESUMO

To determine and compare the antimicrobial effect of Hibiscus sabdariffa calyx extracts, six types of commercial mouthwashes, and chlorhexidine on Streptococcus mutans, Streptococcus sanguinis, Capnocytophaga gingivalis, and Staphylococcus aureus. Two varieties of H. sabdariffa cultivated in Mexico were used. Aqueous, methanolic, ethanolic, acetonic, and ethyl acetate extracts were obtained from H. sabdariffa calyces. Six different types of mouthwash (Astringosol®, Colgate plax-ice-infinity®, Crest pro-health®, Dental max®, Equate®, and Listerine zero®) and chlorhexidine (0.12%) were purchased at a pharmacy. The antimicrobial activity of the H. sabdariffa calyx extracts, mouthwashes, and chlorhexidine was determined by the agar disc diffusion technique. The minimum inhibitory concentration (MIC) and the minimum bactericidal concentration (MBC) of all solutions were determined by the broth dilution method and the pour plate technique, respectively. Also, the effect of H. sabdariffa extracts and chlorhexidine on permeability of the bacterial membrane was determined by the violet crystal assay. All H. sabdariffa calyx extracts and chlorhexidine showed antibacterial activity against all oral pathogenic bacteria. The mouthwashes showed lower antibacterial effect than H. sabdariffa extracts and chlorhexidine. Dental max showed no antibacterial effect. The MICs and MBCs, respectively, for H. sabdariffa extracts were between 5-20 and 10-20 mg/mL; and for chlorhexidine, between 3-4 and 3-5 mg/mL. For the Listerine®, the MIC and MBC values were between 20-25 and 25-33 mg/mL, respectively. The results of the crystal violet test indicate that H. sabdariffa calyx extracts and chlorhexidine alter the permeability of the bacterial membrane. All H. sabdariffa extracts and chlorhexidine showed significantly greater antimicrobial effect than mouthwashes. This is the first report in which the antimicrobial effect of the H. sabdariffa calyx extracts, mouthwashes, and chlorhexidine is compared.


Assuntos
Clorexidina/farmacologia , Hibiscus/química , Antissépticos Bucais/farmacologia , Extratos Vegetais/farmacologia , Capnocytophaga/efeitos dos fármacos , Permeabilidade da Membrana Celular/efeitos dos fármacos , México , Testes de Sensibilidade Microbiana , Staphylococcus aureus/efeitos dos fármacos , Streptococcus/efeitos dos fármacos
6.
Biomedicines ; 8(5)2020 Apr 28.
Artigo em Inglês | MEDLINE | ID: mdl-32354172

RESUMO

Roselle (Hibiscus sabdariffa L.), also known as jamaica in Spanish, is a perennial plant that grows in tropical and subtropical regions, including China, Egypt, Indonesia, Mexico, Nigeria, Thailand, and Saudi Arabia. It has a long history of uses, mainly focused on culinary, botanical, floral, cosmetic, and medicinal uses. The latter being of great impact due to the diuretic, choleretic, analgesic, antitussive, antihypertensive, antimicrobial, immunomodulatory, hepatoprotective, antioxidant, and anti-cancer effects. These therapeutic properties have been attributed to the bioactive compounds of the plant, mainly phenolic acids, flavonoids, anthocyanins, and organic acids (citric, hydroxycitric, hibiscus, tartaric, malic, and ascorbic). Most literature reviews and meta-analyses on the therapeutic potential of Hibiscus sabdariffa L. (Hs) compounds have not adequately addressed the contributions of its organic acids present in the Hs extracts. This review compiles information from published research (in vitro, in vivo, and clinical studies) on demonstrated pharmacological properties of organic acids found in Hs. The intent is to encourage and aid researchers to expand their studies on the pharmacologic and therapeutic effects of Hs to include assessments of the organic acid components.

7.
Food Res Int ; 126: 108589, 2019 12.
Artigo em Inglês | MEDLINE | ID: mdl-31732028

RESUMO

The aim of the present study was to evaluate extractable (EPP), non-extractable polyphenols (NEPP) and organic acid in Roselle by-product, as well as its potential health beneficial effects in obesity control and their complication in rats fed with high caloric diet. Roselle by-product showed a higher content of dietary fiber and NEPP than Roselle calix, which was was a better source of EPP (P < .05). The UPLC-QTOF MSE analysis allowed the tentative identification of 34 EPP, and 3 hydrolysable polyphenols (NEPP), and 2 organic acids in calyx and by-product. Rats fed with a high caloric diet supplemented with 4% of dietary fiber from by-products and Roselle calyx powder generated a reduction in body weight gain (10% and 14%), adipocytes hypertrophy (17% and 13%) and insulin resistance (48% and 59%) and hepatic steatosis (15% and 25%; respectively) compared with rats fed with a high caloric diet alone. Interestingly, even though Roselle by-product has low EPP contents showed comparable beneficial health effects than Roselle calyces. These effects could be associated with high content of dietary fiber and NEPP. Together, the results of the present study indicate that Roselle by-products could be a potential ingredient to develop functional foods against obesity and its complications.


Assuntos
Fármacos Antiobesidade/análise , Flores/química , Hibiscus/química , Fenóis/análise , Compostos Fitoquímicos/análise , Animais , Antocianinas/análise , Antocianinas/farmacologia , Fármacos Antiobesidade/farmacologia , Fibras na Dieta/análise , Fibras na Dieta/farmacologia , Ácido Elágico/análise , Ácido Elágico/farmacologia , Masculino , Fenóis/farmacologia , Compostos Fitoquímicos/farmacologia , Extratos Vegetais/análise , Extratos Vegetais/farmacologia , Polifenóis/análise , Polifenóis/farmacologia , Quercetina/análise , Quercetina/farmacologia , Ratos , Ratos Wistar
8.
J Sci Food Agric ; 99(2): 596-605, 2019 Jan 30.
Artigo em Inglês | MEDLINE | ID: mdl-29943479

RESUMO

BACKGROUND: The calyxes of roselle (Hibiscus sabdariffa) are recognized for their high nutraceutical value because they decrease body weight and obesity complications. These effects have been attributed mainly to anthocyanins. However, the calyxes comprise important concentration of flavonoids, phenolic, and organic acids, which could also contribute to these effects. The objective of this work was to determine the effect of the Alma Blanca white roselle variety on obesity and hepatic steatosis in high-fat, high-fructose, diet-fed rats and compare its beneficial effects with the red variety (Criolla), which has been more extensively studied. RESULTS: Aqueous and methanolic extracts were prepared from two roselle varieties, Alma Blanca (white) and Criolla (red). The phytochemical profiles were determined using high-performance liquid chromatography-mass spectrometry (HPLC-MS). Criolla extracts contain principally anthocyanins, phenolic acids, and flavonoids. Anthocyanins were not detected in Alma Blanca. The aqueous extracts of both varieties prevented body-weight gain and decreased adipocytes hyperplasia on rats fed a hypercaloric diet. These extracts also protected against hepatic steatosis. These benefits were associated with hibiscus, dimethyl hibiscus, and hydroxycitric acid. CONCLUSION: These results demonstrated that calyxes from Hibiscus sabdariffa contain compounds that are different from anthocyanins, with potential benefits to health. The organic acids were strongly associated with these beneficial health effects. © 2018 Society of Chemical Industry.


Assuntos
Hibiscus/química , Obesidade/tratamento farmacológico , Extratos Vegetais/administração & dosagem , Animais , Antocianinas/administração & dosagem , Antocianinas/química , Cromatografia Líquida de Alta Pressão , Flavonoides/administração & dosagem , Flavonoides/química , Flores/química , Humanos , Masculino , Espectrometria de Massas , Obesidade/metabolismo , Fenóis/administração & dosagem , Fenóis/química , Compostos Fitoquímicos/administração & dosagem , Compostos Fitoquímicos/química , Extratos Vegetais/química , Ratos , Ratos Wistar
9.
Lett Appl Microbiol ; 62(2): 177-84, 2016 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-26612600

RESUMO

UNLABELLED: Antibiotic-resistant Salmonella strains were isolated from saladette and red round type tomatoes, and an analysis done of the antibacterial activity of roselle calyx extracts against any of the identified strains. One hundred saladette tomato samples and 100 red round tomato samples were collected from public markets. Each sample consisted of four whole tomatoes. Salmonella was isolated from the samples by conventional culture procedure. Susceptibility to 16 antibiotics was tested for the isolated Salmonella strains by standard test. The antibacterial effect of four roselle calyx extracts (water, methanol, acetone and ethyl acetate), sodium hypochlorite and acetic acid against antibiotic-resistant Salmonella isolates was evaluated on contaminated tomatoes. Twenty-four Salmonella strains were isolated from 12% of each tomato type. Identified Salmonella serotypes were Typhimurium and Typhi. All isolated strains exhibited resistance to at least three antibiotics and some to as many as 12. Over contaminated tomatoes, the roselle calyx extracts produced a greater reduction (2-2·6 log) in antibiotic-resistant Salmonella strain concentration than sodium hypochlorite and acetic acid. SIGNIFICANCE AND IMPACT OF THE STUDY: The presence of multidrug-resistant Salmonella in vegetables is a significant public health concern. Multidrug-resistant Salmonella strains were isolated from raw tomatoes purchased in public markets in Mexico and challenged with roselle Hibiscus sabdariffa calyx extracts, sodium hypochlorite and acetic acid. On tomatoes, the extracts caused a greater reduction in the concentration of antibiotic-resistant Salmonella strains than sodium hypochlorite and acetic acid. Roselle calyx extracts are a potentially useful addition to disinfection procedures of raw tomatoes in the field, processing plants, restaurants and homes.


Assuntos
Ácido Acético/farmacologia , Desinfetantes/farmacologia , Hibiscus/metabolismo , Extratos Vegetais/farmacologia , Salmonella typhi/efeitos dos fármacos , Salmonella typhimurium/efeitos dos fármacos , Hipoclorito de Sódio/farmacologia , Solanum lycopersicum/microbiologia , Antibacterianos/farmacologia , Desinfecção/métodos , Farmacorresistência Bacteriana Múltipla , Doenças Transmitidas por Alimentos/microbiologia , Doenças Transmitidas por Alimentos/prevenção & controle , México , Testes de Sensibilidade Microbiana , Salmonella typhi/isolamento & purificação , Salmonella typhimurium/isolamento & purificação
10.
Braz. J. Biol. ; 75(1): 69-76, Jan-Mar/2015. tab, graf
Artigo em Inglês | VETINDEX | ID: vti-9724

RESUMO

The aim of this study was to evaluate the phenolic and flavonoids contents and the antioxidant and antitumoral activity of leaf and calyx methanolic extracts from Hibiscus sabdariffa (roselle) cultivated with poultry litter and organosuper® under three modes of application. The total phenolic content in the each extract was determined using the Folin-Ciocalteu reagent and for aluminium chloride flavonoids. The antioxidant parameters were analyzed using a 2, 2-diphenyl-1-picrylhydrazyl (DPPH.) free radical scavenging assay. An antitumor colorimetric assay using sulforhodamine B. The highest contents of phenolic and flavonoids were observed in leaf extracts (389.98 and 104.52 mg g–1, respectively) and calyx extracts (474.09 and 148.35 mg g–1, respectively) from plants cultivated with organosuper®, although these values did not differ significantly from those observed for the other treatments. The average IC50 of leaves (43.48 μg mL–1) and calyces (37.15 μg mL–1) demonstrated that both have substances that may contribute to free radical scavenging action. The methanol extract from calyces showed significant selective activity against a leukemia line (K-562), with IC50 values of 0.12 mg mL–1 (organosuper®) and 1.16 mg mL–1 (poultry litter), with concentration-dependent, cytotoxic and cytocidal effects.(AU)


O objetivo deste estudo foi avaliar a atividade antioxidante, antitumoral e o conteúdo de fenólicos e flavonoides do extrato metanólico das folhas e cálices de Hibiscus sabdariffa (rosela) cultivada com cama de frango e organosuper ® em três modos de aplicação. O conteúdo fenólico total de cada extrato foi determinado utilizando o reagente de Folin-Ciocalteu e cloreto de alumínio para flavonoides. Os parâmetros antioxidantes foram avaliados pelo ensaio de seqüestro de radical livre 2, 2-difenil-1-picrilhidrazil (DPPH.). Na avaliação antitumoral utilizou-se o ensaio colorimétrico com sulforrodamina B. Observou-se o maior conteúdo de fenólicos e flavonoides em extratos de folhas (389.98 e 104.52 mg g–1, respectivamente) e extratos de cálice (474.09 e 148.35 mg g–1, respectivamente) de plantas cultivadas com organosuper ®, embora esses valores não diferiram significativamente daqueles observados para os outros tratamentos. O IC50 de folhas (43.48 µg mL–1) e cálices (37.15 µg mL–1) demonstrou que ambos têm substâncias que podem contribuir para a ação seqüestradora de radicais livres. O extrato metanólico dos cálices mostrou seletividade na linhagem de leucemia (K-562), com valores de IC50 de 0,12 mg mL–1 (organosuper®) e 1,16 mg mL–1 (cama-de-frango) com concentração-dependente e efeito citotóxico e citocida.(AU)


Assuntos
Humanos , Antioxidantes/farmacologia , Proliferação de Células , Hibiscus/química , Fenóis/química , Extratos Vegetais/farmacologia , Antineoplásicos Fitogênicos/isolamento & purificação , Antioxidantes/isolamento & purificação , Linhagem Celular Tumoral , Ensaios de Seleção de Medicamentos Antitumorais , Folhas de Planta/química
11.
Braz. j. biol ; Braz. j. biol;75(1): 69-76, Jan-Mar/2015. tab, graf
Artigo em Inglês | LILACS | ID: lil-744335

RESUMO

The aim of this study was to evaluate the phenolic and flavonoids contents and the antioxidant and antitumoral activity of leaf and calyx methanolic extracts from Hibiscus sabdariffa (roselle) cultivated with poultry litter and organosuper® under three modes of application. The total phenolic content in the each extract was determined using the Folin-Ciocalteu reagent and for aluminium chloride flavonoids. The antioxidant parameters were analyzed using a 2, 2-diphenyl-1-picrylhydrazyl (DPPH.) free radical scavenging assay. An antitumor colorimetric assay using sulforhodamine B. The highest contents of phenolic and flavonoids were observed in leaf extracts (389.98 and 104.52 mg g–1, respectively) and calyx extracts (474.09 and 148.35 mg g–1, respectively) from plants cultivated with organosuper®, although these values did not differ significantly from those observed for the other treatments. The average IC50 of leaves (43.48 μg mL–1) and calyces (37.15 μg mL–1) demonstrated that both have substances that may contribute to free radical scavenging action. The methanol extract from calyces showed significant selective activity against a leukemia line (K-562), with IC50 values of 0.12 mg mL–1 (organosuper®) and 1.16 mg mL–1 (poultry litter), with concentration-dependent, cytotoxic and cytocidal effects.


O objetivo deste estudo foi avaliar a atividade antioxidante, antitumoral e o conteúdo de fenólicos e flavonoides do extrato metanólico das folhas e cálices de Hibiscus sabdariffa (rosela) cultivada com cama de frango e organosuper ® em três modos de aplicação. O conteúdo fenólico total de cada extrato foi determinado utilizando o reagente de Folin-Ciocalteu e cloreto de alumínio para flavonoides. Os parâmetros antioxidantes foram avaliados pelo ensaio de seqüestro de radical livre 2, 2-difenil-1-picrilhidrazil (DPPH.). Na avaliação antitumoral utilizou-se o ensaio colorimétrico com sulforrodamina B. Observou-se o maior conteúdo de fenólicos e flavonoides em extratos de folhas (389.98 e 104.52 mg g–1, respectivamente) e extratos de cálice (474.09 e 148.35 mg g–1, respectivamente) de plantas cultivadas com organosuper ®, embora esses valores não diferiram significativamente daqueles observados para os outros tratamentos. O IC50 de folhas (43.48 µg mL–1) e cálices (37.15 µg mL–1) demonstrou que ambos têm substâncias que podem contribuir para a ação seqüestradora de radicais livres. O extrato metanólico dos cálices mostrou seletividade na linhagem de leucemia (K-562), com valores de IC50 de 0,12 mg mL–1 (organosuper®) e 1,16 mg mL–1 (cama-de-frango) com concentração-dependente e efeito citotóxico e citocida.


Assuntos
Humanos , Antineoplásicos Fitogênicos/farmacologia , Antioxidantes/farmacologia , Proliferação de Células/efeitos dos fármacos , Hibiscus/química , Fenóis/química , Extratos Vegetais/farmacologia , Antineoplásicos Fitogênicos/isolamento & purificação , Antioxidantes/isolamento & purificação , Linhagem Celular Tumoral , Ensaios de Seleção de Medicamentos Antitumorais , Folhas de Planta/química
12.
Food Chem ; 172: 885-92, 2015 Apr 01.
Artigo em Inglês | MEDLINE | ID: mdl-25442634

RESUMO

Plant infusions are consumed due to their beneficial effects on health, which is attributed to their bioactive compounds content. However, these compounds are susceptible to degradation during processing and storage. The objective of this research was to evaluate the effect of stevia and citric acid on the stability of phenolic compounds, antioxidant capacity and carbohydrate-hydrolysing enzyme inhibitory activity of roselle beverages during storage. The optimum extraction conditions of roselle polyphenolic compounds was of 95 °C/60 min, which was obtained by a second order experimental design. The incorporation of stevia increased the stability of colour and some polyphenols, such as quercetin, gallic acid and rosmarinic acid, during storage. In addition, stevia decreased the loss of ABTS, DPPH scavenging activity and α-amylase inhibitory capacity, whereas the incorporation of citric acid showed no effect. These results may contribute to the improvement of technological processes for the elaboration of hypocaloric and functional beverages.


Assuntos
Antioxidantes/química , Bebidas/análise , Ácido Cítrico/análise , Diterpenos do Tipo Caurano/análise , Glucosídeos/análise , Hibiscus/química , Hipoglicemiantes/química , Fenóis/química , Extratos Vegetais/química , Aditivos Alimentares/análise
13.
Clinics ; Clinics;68(10): 1358-1363, out. 2013. tab, graf
Artigo em Inglês | LILACS | ID: lil-689976

RESUMO

OBJECTIVES: The aim of this study was to investigate the protective effects of aqueous extracts of roselle (Hibiscus sabdariffa L. UKMR-2) against red blood cell (RBC) membrane oxidative stress in rats with streptozotocin-induced diabetes. METHODS: Forty male Sprague-Dawley rats weighing 230-250 g were randomly divided into four groups (n = 10 rats each): control group (N), roselle-treated control group, diabetic group, and roselle-treated diabetic group. Roselle was administered by force-feeding with aqueous extracts of roselle (100 mg/kg body weight) for 28 days. RESULTS: The results demonstrated that the malondialdehyde levels of the red blood cell membranes in the diabetic group were significantly higher than the levels in the roselle-treated control and roselle-treated diabetic groups. The protein carbonyl level was significantly higher in the roselle-treated diabetic group than in the roselle-treated control group but lower than that in the diabetic group. A significant increase in the red blood cell membrane superoxide dismutase enzyme was found in roselle-treated diabetic rats compared with roselle-treated control rats and diabetic rats. The total protein level of the red blood cell membrane, osmotic fragility, and red blood cell morphology were maintained. CONCLUSION: The present study demonstrates that aqueous extracts of roselle possess a protective effect against red blood cell membrane oxidative stress in rats with streptozotocin-induced diabetes. These data suggest that roselle can be used as a natural antioxidative supplement in the prevention of oxidative damage in diabetic patients. .


Assuntos
Animais , Masculino , Ratos , Diabetes Mellitus Experimental/metabolismo , Membrana Eritrocítica/efeitos dos fármacos , Hibiscus/química , Estresse Oxidativo/efeitos dos fármacos , Extratos Vegetais/farmacologia , Antioxidantes/farmacologia , Peso Corporal , Diabetes Mellitus Experimental/induzido quimicamente , Membrana Eritrocítica/química , Malondialdeído/sangue , Ratos Sprague-Dawley , Reprodutibilidade dos Testes , Estreptozocina , Superóxido Dismutase/sangue , Fatores de Tempo , Resultado do Tratamento
14.
Arch. latinoam. nutr ; Arch. latinoam. nutr;60(1): 79-84, mar. 2010. tab
Artigo em Espanhol | LILACS | ID: lil-588616

RESUMO

Fibra dietética y compuestos antioxidantes son dos conceptos que generalmente se utilizan por separado tanto en la industria como en nutrición. Actualmente el concepto de fibra se ha ampliado debido a que en los alimentos hay otros componentes diferentes a polisacáridos y lignina que no son digeridos en el intestino delgado y que pasan al intestino grueso constituyendo la mayor parte del substrato para la microbiota colónica. El concepto de fibra antioxidante se refiere a aquella materia prima con un elevado porcentaje de fibra dietética y cantidades apreciables de antioxidantes naturales asociados a la matriz del conjunto de compuestos no digestibles. Las flores de Hibiscus sabdariffa L, presentan en su composición un porcentaje importante de fibra dietética así como una elevada capacidad antioxidante. La infusión que se obtiene de la decocción de los cálices de Hibiscus, ha sido ampliamente estudiada debido a las propiedades saludables que se le confieren. En este trabajo se consideran los principales aspectos nutricionales de Hibiscus sabdariffa L y se plantea la posibilidad de estudiarlos como una posible fuente de fibra antioxidante, con propiedades funcionales de interés nutricional.


Dietary fiber and antioxidants are food constituents and functional ingredients that are generally addressed separately. Nowadays there is scientific evidence that primary characteristics of DF assigned to non starch polysaccharides and lignin (resistance to digestion and absorption in the small intestine and fermentation in the large intestine) can be extended to other indigestible food constituents that are resistant to digestion and absorption in the human small intestine with complete or partial fermentation in the large intestine. The antioxidant dietary fiber concept was defined as a dietary fiber concentrate containing significant amounts of natural antioxidants associated with non digestible compounds. Hibiscus sabdariffa L flower shows in its composition an important percentage of dietary fiber and high antioxidant capacity. The infusion obtained by decoction of flowers, had been extensibility studied due to the healthy properties. In this work the principal nutritional aspects from Hibiscus sabdariffa L and its use as a possible antioxidant dietary fiber source had been considered.


Assuntos
Antioxidantes , Fibras na Dieta , Hibiscus , Compostos Fenólicos
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