RESUMO
OBJECTIVE: To determine the prevalence of open angle glaucoma in a hospital-based sample of diabetic people living in Martinique. DESIGN: Retrospective study during 23 months. PARTICIPANTS: A total of 917 patients were examined and received a complete eye examination for diabetes. MAIN OUTCOME MEASURES: A form was established with all examination data, patient ID, non ophthalmological data (blood pressure, body mass index, type of diabetes...) and ophthalmological data with intra-ocular pressure and optic disc cup. RESULTS: Glaucoma was present in about 9.8 percent of patients and there were 3.28 times more females than male. With regard to the type of diabetes, 1.11 percent were type 1, 18.89 percent were type 2, and 80 percent were insulin treated but not all insulin dependent. The prevalence of diabetic retinopathy is similar in the glaucomatous group and in the non-glaucomatous group. High blood pressure was present in 80 percent of glaucoma patients versus 58.8 percent in the non-glaucoma group. CONCLUSION: This 9.8 percent prevalence of glaucoma is the only data on open angle glaucoma so far available in Martinique. High blood pressure is a main risk factor for glaucoma in Martinique. Diabetes represents also a risk factor for glaucoma in Martinique. The sex ratio showed 3 times more females than males in the diabetic population. (AU)
Assuntos
Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Retinopatia Diabética/tratamento farmacológico , Glaucoma de Ângulo AbertoRESUMO
HLA-A,B,C, and DR frequencies have been determined in 34 Coloured Martinican IDDM patients to establish the HLA and IDDM associations. HLA A3, B15, B18, Cw3 and DR4 antigens associations with IDDM are confirmed by this study. We found an increase of B21 similar to that found in Asiatic Indians. As in some African Black populations and in Cape coloured people, A1, B8, and DR3 are not increased in our population. We should point out that our patients' ages of onset were low, and that some studies have found DR4 association in young patients and DR3 in older ones. The protective role of DR2 is confirmed here. B35 and Cw4 negative associations have been found. We have observed that the antigens associated with IDDM are decreased in our control population, except DR4, and that the negative associated DR/ and Cw4 antigens are increased compared to the Continental French population. This corresponds with the low IDDM incidence in Blacks and Coloured people.