RESUMO
The aim of this research was to evaluate the storage stability (5⯰C), and microbial modeling, of Rubi red grapefruit (Citrusâ¯×â¯paradisi) juice treated with ultraviolet-C (UV-C) light (0, 10 and 20â¯min), alone or in combination with trans-cinnamaldehyde (trans-CAH) (0, 25 and 50⯵g/mL). A 32 factorial design was used and data modeled with the Weibull, Modified Gompertz and Logistic models. A response surface model was used to evaluate the effect of modeling parameters for suggesting the optimum treatment conditions. Treated and some untreated juice lasted up to 9â¯days without physicochemical and microbial changes. At the higher combination of UV-C light and trans-CAH, the microbial load of grapefruit juice was maintained below 100â¯CFU/mL up to 15â¯days. For mesophiles, the three predictive models indicated that the parameters n and Nmax decreased and the parameters λ and tc increased as the combination of UV-C light and trans-CAH increased. The response surface modeling of the parameters obtained by the predictive models showed acceptable correlation for mesophiles (R2â¯=â¯0.815-0.977) but not for yeasts (R2â¯=â¯0.618-0.815). The three predictive models showed that, the concentration of trans-CAH had more effect on stopping the microbial growth than the UV-C light treatment.
Assuntos
Acroleína/análogos & derivados , Bactérias/efeitos dos fármacos , Bactérias/efeitos da radiação , Citrus paradisi/microbiologia , Conservação de Alimentos/métodos , Sucos de Frutas e Vegetais/microbiologia , Acroleína/química , Acroleína/farmacologia , Bactérias/crescimento & desenvolvimento , Irradiação de Alimentos/métodos , Conservação de Alimentos/instrumentação , Sucos de Frutas e Vegetais/análise , Humanos , Raios UltravioletaRESUMO
The increase in the elderly population has generated concern to meet health demands. The research efforts to elucidate the mechanisms of damage associated with aging have also been significantly increased, especially in order to avoid the reduction of the cognitive abilities in geriatric patients, resulting from the damage generated mainly at the level of the hippocampus during old age. At present, many studies describe resveratrol as an antiaging component. There are reports that it can activate the Sirt1 gene related to antiaging, emulating the effects obtained by caloric restriction in rodents. The aim of the study was to evaluate the effect of chronic administration of resveratrol (10 mg/kg) on cognitive performance in behavioral tests after 8 months of treatment and on the preservation of cerebral integrity in the cytoarchitecture of regions CA1 and CA2. Results showed that the cytoarchitecture of the CA1 and CA2 regions in the hippocampus retained their integrity over time in rats treated with resveratrol, and the behavioral test performed revealed that chronic resveratrol administration for 8 months showed improvements in cognitive performance. The results indicate that resveratrol may exhibit therapeutic potential for age-related conditions.