Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 2 de 2
Filtrar
Mais filtros











Intervalo de ano de publicação
1.
P R Health Sci J ; 15(3): 187-91, 1996 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-8994283

RESUMO

Clear differences exist in the incidence and severity of atherosclerotic plaques that arise in different segments of the arterial tree. Aortic homograft transplant experiments in dogs showed that the greater incidence of plaque formation in the abdominal versus the thoracic aorta was due to intrinsic differences in the cell populations in these two segments rather than to hemodynamic factors. What is the basis for SMC diversity within a common vessel wall? Recent lineage analysis studies in the avian and mammalian embryo indicate that two distinct SMC lineages contribute to the formation of the major elastic outflow arteries including the aorta. A mixture of unique SMC types of diverse developmental lineages within a common vessel wall raises new questions about the potential for SMC type-specific responses to growth factors and cytokines involved in human atherosclerosis and restenosis.


Assuntos
Angioplastia Coronária com Balão/efeitos adversos , Doença das Coronárias/patologia , Doença das Coronárias/terapia , Modelos Animais de Doenças , Matriz Extracelular/patologia , Músculo Liso Vascular/patologia , Animais , Aorta Abdominal/patologia , Aorta Torácica/patologia , Linhagem da Célula , Citocinas/fisiologia , Cães , Substâncias de Crescimento/fisiologia , Humanos , Músculo Liso Vascular/embriologia , Neovascularização Patológica/fisiopatologia , Ratos , Recidiva
2.
P. R. health sci. j ; P. R. health sci. j;15(3): 187-91, Sept. 1996.
Artigo em Inglês | LILACS | ID: lil-228510

RESUMO

Clear differences exist in the incidence and severity of atherosclerotic plaques that arise in different segments of the arterial tree. Aortic homograft transplant experiments in dogs showed that the greater incidence of plaque formation in the abdominal versus the thoracic aorta was due to intrinsic differences in the cell populations in these two segments rather than to hemodynamic factors. What is the basis for SMC diversity within a common vessel wall? Recent lineage analysis studies in the avian and mammalian embryo indicate that two distinct SMC lineages contribute to the formation of the major elastic outflow arteries including the aorta. A mixture of unique SMC types of diverse developmental lineages within a common vessel wall raises new questions about the potential for SMC type-specific responses to growth factors and cytokines involved in human atherosclerosis and restenosis


Assuntos
Animais , Cães , Humanos , Ratos , Angioplastia Coronária com Balão/efeitos adversos , Doença das Coronárias/patologia , Doença das Coronárias/terapia , Modelos Animais de Doenças , Matriz Extracelular/patologia , Músculo Liso Vascular/patologia , Aorta Abdominal/patologia , Aorta Torácica/patologia , Linhagem da Célula , Citocinas/fisiologia , Substâncias de Crescimento/fisiologia , Músculo Liso Vascular/embriologia , Neovascularização Patológica/fisiopatologia , Recidiva
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA