RESUMO
OBJECTIVE: To compare the prevalence of dental anomalies in patients with isolated cleft palate with or without hypodontia of the second premolar. SETTING AND SAMPLE POPULATION: A total of 653 patients with isolated cleft palate aged 8-12 years were divided into two groups: G1-subjects without hypodontia of second premolar (n = 546) and G2-subjects with hypodontia of at least one-second premolar (n = 107). The control group consisted of 107 non-cleft orthodontic patients. MATERIALS & METHODS: Panoramic and periapical radiographs and dental casts were used to analyze the presence of dental anomalies. Intergroup comparisons were performed using the chi-square test complemented by Proportion test and Bonferroni test. RESULTS: G2 presented higher prevalence of hypodontia of other permanent teeth compared to G1 and control. Ectopic eruption of the maxillary canine and tooth transposition were more frequent in patients with a cleft compared to patients without a cleft, without statistical differences. Deciduous molar infra-occlusion and second premolar disto-angulation were less prevalent in G1 and G2 compared to the control group. G2 showed a higher prevalence of complete cleft palate than G1. CONCLUSION: Patients with cleft palate and second premolar agenesis showed increased prevalence of tooth agenesis and palatally displaced canines.
Assuntos
Anodontia/epidemiologia , Dente Pré-Molar/anormalidades , Fissura Palatina/epidemiologia , Anodontia/diagnóstico por imagem , Dente Pré-Molar/diagnóstico por imagem , Brasil/epidemiologia , Criança , Comorbidade , Dente Canino/diagnóstico por imagem , Feminino , Humanos , Masculino , Má Oclusão/diagnóstico por imagem , Má Oclusão/epidemiologia , Fenótipo , PrevalênciaRESUMO
OBJECTIVE: This report is a retrospective study that compares the craniofacial morphology of adult subjects with unoperated bilateral complete cleft lip and palate (BCLP) with that of a noncleft group. METHODS: The study was performed on standardized lateral cephalograms obtained at the Hospital for Research and Rehabilitation of Cleft Lip and Palate, University of São Paulo, Brazil. The research group consisted of 28 subjects (20 males, 8 females) with unoperated BCLP, ranging in age from 15 to 41 years. The control group was matched to the cleft group with regard to gender and age. The findings were analyzed on the basis of the two-way analysis of variance (ANOVA) for cleft and gender. RESULTS: The most striking difference between the groups was the extremely prominent premaxilla in the cleft group that gave the BCLP face a very convex profile. The mandible exhibited a vertical growth pattern that resulted in a steep mandibular plane, an obtuse gonial angle and a long lower face height. The posterior face height was reduced. The cranial base dimensions were smaller, but there was no difference in cranial base angulation. CONCLUSIONS: These findings confirm that in subjects with unoperated BCLP, the initial characteristics of the cleft malformation persist during growth.
Assuntos
Fenda Labial/fisiopatologia , Fissura Palatina/fisiopatologia , Ossos Faciais/anormalidades , Ossos Faciais/crescimento & desenvolvimento , Desenvolvimento Maxilofacial , Adolescente , Adulto , Análise de Variância , Estudos de Casos e Controles , Cefalometria , Ossos Faciais/anatomia & histologia , Feminino , Humanos , Incisivo/anormalidades , Masculino , Estudos Retrospectivos , Caracteres Sexuais , Base do Crânio/crescimento & desenvolvimento , Dimensão VerticalRESUMO
We report on mandibulofacial dysostosis in 2 brothers born to normal nonconsanguineous parents, and a girl (F = 1/16) born to normal consanguineous parents. Normal clinical, skeletal, audiologic, and cephalometric studies in the parents, as well as the absence of limb anomalies in these children, exclude the autosomal recessive (Nager and Genée-Widemann) mandibulofacial dysostoses. The data of the present patients associated with the few additional reports on mandibulofacial dysostosis recurring in sibs, suggest the possibility of an autosomal recessive Treacher Collins-like mandibulofacial dysostosis.