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RESUMEN En Chile los armadillos Zaedyus pichiy (Desmarest, 1804) y Chaetophractus villosus (Desmarest, 1804) tienen poblaciones periféricas restringidas a planicies de altura y estepa patagónica en la vertiente occidental de la Cordillera de los Andes, donde además han sido escasamente estudiadas. En este trabajo entregamos información sobre los hábitos alimenticios de ambas especies de armadillos, obtenida mediante el análisis de heces colectadas en dos áreas de la región de Aysén, Patagonia chilena. En 38 heces de Z. pichiy identificamos dos taxones de plantas, seis de invertebrados y cuatro de vertebrados, mientras que en 72 heces C. villosus identificamos tres, nueve y cuatro taxones de las mismas categorías. En ambas especies de armadillos los invertebrados fueron la categoría más diversa y con mayor frecuencia de ocurrencia, siendo Coleoptera, Orthoptera y Hemiptera los grupos mejor representados en términos de abundancia. Entre los vertebrados se observó mayor frecuencia de restos del camélido Lama guanicoe (Müller, 1776) y el lagomorfo Lepus europaeus (Pallas, 1778). El análisis de rarefacción muestra que la riqueza de taxones fue mayor en C. villosus que en Z. pichiy, y el índice de Pianka indica que no existió un solapamiento trófico significativo entre especies de armadillos. Nuestras observaciones indican que poblaciones periféricas de ambas especies de armadillos muestran dietas omnívoras oportunistas, con un mayor consumo de invertebrados y plantas; además, sugieren que C. villosus se desarrolla en un rango ambiental más amplio, con una dieta más diversa y mayor presencia de esta especie en ambas áreas de estudio.
ABSTRACT In Chile the armadillos Zaedyus pichiy (Desmarest, 1804) and Chaetophractus villosus (Desmarest, 1804) have peripheral populations restricted to steppes and plains near western slopes of the Andes, being also inadequately studied. We present information on feeding habits of both species by analysis of feces obtained in two study areas of Aysén district, Chilean Patagonia. In 38 feces of Z. pichiy we identified two plant taxa, six invertebrate and four vertebrate; in 72 feces of C. villosus we identified three plant taxa, nine invertebrate and four vertebrate. In both armadillos species the invertebrates were the category more frequent and diverse. Coleoptera, Orthoptera and Hemiptera were the most abundant insects, and remains of ungulate Lama guanicoe (Müller, 1776) and lagomorph Lepus europaeus (Pallas, 1778) were the most frequent vertebrates. The rarefaction analysis indicates higher taxa richness in C. villosus than in Z pichiy and Pianka index indicates there is no significant trophic overlap between these two species of armadillos. Our results indicate omnivores/opportunistic foods habits in peripheral populations of both species, with higher consumption of invertebrates and plants; also they suggest that C. villosus lives in a broader environmental range, with a more diverse food habits and higher abundance in both study areas.
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Agranulocytosis is a rare side effect of antithyroid drugs, it occurs in less than 0.5% of patients, usually during the first few months of treatment. It is considered to be the most serious adverse effect of these medications since it may be complicated by serious, life-threatening infections. Mucormycosis is a severe mycotic infection that usually develops in immunocompromised hosts, such aspatients with diabetes mellitus, hematologic malignancies or immunosuppressive therapy. The association of mucormycosis with methimazole-induced agranulocytosis has not been previously described. The objective of this case presentation is to analyze the case ofa woman with diffuse toxic goiter and methimazole-induced agranulocytosis who developed rhino-palatal mucormycosis.
Assuntos
Agranulocitose/induzido quimicamente , Antitireóideos/efeitos adversos , Metimazol/efeitos adversos , Mucormicose/induzido quimicamente , Adulto , Feminino , HumanosRESUMO
La agranulocitosis es una complicación poco frecuente de los medicamentos antitiroideos, se presenta en menos de 0.5% de los pacientes en los primeros meses de tratamiento. Se considera el efecto adverso más grave de estos medicamentos, ya que se puede complicar con infecciones severas con una tasa alta de mortalidad. La mucormicosis es una infección micótica severa observada en huéspedes inmunocomprometidos como pacientes con diabetes, neoplasias hematológicas o con tratamiento inmunosupresor; sin embargo, la asociación de mucormicosis con agranulocitosis por metimazol no se ha reseñado previamente. El objetivo de este informe es analizar el caso de una mujer con bocio tóxico difuso y agranulocitosis asociada a metimazol, quien desarrolló mucormicosis rinopalatina.
Agranulocytosis is a rare side effect of antithyroid drugs, it occurs in less than 0.5% of patients, usually during the first few months of treatment. It is considered to be the most serious adverse effect of these medications since it may be complicated by serious, life-threatening infections. Mucormycosis is a severe mycotic infection that usually develops in immunocompromised hosts, such aspatients with diabetes mellitus, hematologic malignancies or immunosuppressive therapy. The association of mucormycosis with methimazole-induced agranulocytosis has not been previously described. The objective of this case presentation is to analyze the case ofa woman with diffuse toxic goiter and methimazole-induced agranulocytosis who developed rhino-palatal mucormycosis.
Assuntos
Humanos , Feminino , Adulto , Antitireóideos , Agranulocitose/induzido quimicamente , Metimazol/efeitos adversos , Mucormicose/induzido quimicamenteRESUMO
Background. Thyrotoxic periodic paralysis (TPP) is characterized by episodes of neuromuscular weakness occurring in the context of hypokalemia and hyperthyroidism and has been predominantly described in Oriental populations. Whereas it is uncommon in Caucasians and Blacks, TPP does occur in individuals of Native American descent. The objective was to analyze the clinical, biochemical, and HLA characteristics of group of Mexican mestizo patients with TPP. Methods. The sample was comprised of 14 men with TPP diagnosed since january 1990, based on one or more episodes of flaccid paralysis, accompanied by hypokalemia and occurring in the context of clinical and biochemical hyperthyroidism. Eight were available HLA testing. Results. Hyperthyroidsm was diagnosed before the development of periodic paralysis in five of the patients, whereas in six it occurred afterward. The severity of paralysis did not correlate with the degree of either hypokalemia or hyperthyroidism. An increased frequency of HLA-DR3 was found in Graves' patients without paralysis but not in those with paralysis, as compared to the general population. Conclusions. TPP is more common than previously thoought in Mexicans, in whom it behaves as in other Native American groups. The lack of HLA-DR3 association in Graves' patients with TPP is interesting, but at the moment has no pathophysiological implications
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Humanos , Masculino , Adulto , Pessoa de Meia-Idade , Antígenos HLA/análise , Etnicidade , Frequência do Gene , Doença de Graves/complicações , População Branca/genética , Hipopotassemia/etnologia , Paralisia/etnologia , Tireotoxicose/etnologia , /análise , Antígenos HLA/genética , Frequência do Gene , Doença de Graves/imunologia , Hipopotassemia/sangue , Indígenas Norte-Americanos/genética , Paralisia/sangue , Potássio/sangue , Hormônios Tireóideos/sangue , Tireotoxicose/etiologiaRESUMO
Most cases of primary hyperparathyroidism are due to either a parathyroid adenoma or to parathyroid hyperplasia. Parathyroid carcinoma is a very rare cause of hyperparathyroidism. Although the diagnosis of parathyroid carcinoma is usually established based on pathological criteria of vascular and capsular invasion, some clinical and biochemical features differentiate it from benign forms of hyperparathyroidism. We report the case of a middle-aged woman with a long standing history of nephrolithiasis, who presented with a palpable neck mass, wigh loss, severe hypercalcemia and hypophosphatemia, as well as very high serum levels of intact parathyroid hormone. Surgical neck exploration revealed a large tumor that invaded trache, esophagus, recurrent laryngeal nerve, right apical pleura and right carotid artery. Pathological examination confirmed the invasive nature of the tumor. Along with the case report, we review the literature and discuss the diagnostic and therapeutic options of this rare condition