RESUMO
BACKGROUND: International collaboration is increasingly used in biomedical research. AIM: To describe the characteristics of scientific production in Latin America and the main international collaboration networks for the period 2000 to 2009. MATERIAL AND METHODS: Search for papers generated in Latin American countries in the Clinical Medicine database of ISI Web of Knowledge v.4.10 - Current Contents Connect. The country of origin of the corresponding author was considered the producing country of the paper. International collaboration was analyzed calculating the number of countries that contributed to the generation of a particular paper. Collaboration networks were graphed to determine the centrality of each network. RESULTS: Twelve Latin American countries participated in the production of 253,362 papers. The corresponding author was South American in 79% of these papers. Sixteen percent of papers were on clinical medicine and 36% of these were carried out in collaboration. Brazil had the highest production (22,442 papers) and the lower percentage of international collaboration (31%). North America accounts for 63% of collaborating countries. Only 8% of collaboration is between South American countries. Brazil has the highest tendency to collaborate with other South American countries. CONCLUSIONS: Brazil is the South American country with the highest scientific production and indicators of centrality in South America. The most common collaboration networks are with North American countries.
Assuntos
Bibliometria , Medicina Clínica/estatística & dados numéricos , Cooperação Internacional , Publicações Periódicas como Assunto , Editoração/estatística & dados numéricos , Pesquisa Biomédica/estatística & dados numéricos , América do SulRESUMO
Background: International collaboration is increasingly used in biomedical research. Aim: To describe the characteristics of scientific production in Latin America and the main international collaboration networks for the period 2000 to 2009. Material and Methods: Search for papers generated in Latin American countries in the Clinical Medicine database of ISI Web of Knowledge v.4.10 - Current Contents Connect. The country of origin of the corresponding author was considered the producing country of the paper. International collaboration was analyzed calculating the number of countries that contributed to the generation of a particular paper. Collaboration networks were graphed to determine the centrality of each network. Results: Twelve Latin American countries participated in the production of253,362 papers. The corresponding author was South American in 79% of these papers. Sixteen percent of papers were on clinical medicine and 36% of these were carried out in collaboration. Brazil had the highest production (22,442 papers) and the lower percentage of international collaboration (31%). North America accounts for 63% of collaborating countries. Only 8% of collaboration is between South American countries. Brazil has the highest tendency to collaborate with other South American countries. Conclusions: Brazil is the South American country with the highest scientific production and indicators of centrality in South America. The most common collaboration networks are with North American countries.
Assuntos
Bibliometria , Medicina Clínica/estatística & dados numéricos , Cooperação Internacional , Publicações Periódicas como Assunto , Editoração/estatística & dados numéricos , Pesquisa Biomédica/estatística & dados numéricos , América do SulRESUMO
Occasionally hepatectomy for metastases of ampulla of Vater carcinoma can result in a better survival and quality of life of patients. We report a 67 years old male subjected to a duodenopancreatectomy for a carcinoma of the ampulla of Vater that required afterwards a right hepatectomy for metastases. Twenty one months after the second operation and 42 months after the first operation, that patient is asymptomatic and without evidences of relapse.
El tratamiento quirúrgico del carcinoma de ampolla de Vater presenta mejores resultados oncológicos que los del resto de los tumores periampulares. En casos seleccionados, la resección hepática por metástasis de carcinoma de ampolla de Vater extirpado previamente, puede proporcionar supervivencias prolongadas y con buena calidad de vida. Presentamos un paciente de 67 años tratado con duodenopancreatectomía por cáncer de la ampolla de Vater y posteriormente con hepatectomía derecha por metástasis. A los 42 y 21 meses de la primera y segunda intervención respectivamente, permanece asintomático y sin evidencia de enfermedad.
Assuntos
Humanos , Masculino , Idoso , Ampola Hepatopancreática/patologia , Carcinoma/cirurgia , Carcinoma/secundário , Neoplasias Hepáticas/cirurgia , Neoplasias Hepáticas/secundário , Neoplasias do Ducto Colédoco/patologia , Ampola Hepatopancreática/cirurgia , Hepatectomia , Neoplasias do Ducto Colédoco/cirurgia , Pancreaticoduodenectomia , Resultado do TratamentoRESUMO
Oculopharyngeal muscular dystrophy (OPMD) is a rare myopathy that is characterized by ocular and pharyngeal muscle involvement. OPMD typically presents with ptosis, dysarthria, and dysphagia. It can also be associated with proximal and distal extremity weakness. We report two patients with the disease. A 79 years old female presenting with ptosis, dysphagia and a history of three aspiration pneumonias. The patient was subjected to a myotomy of the cricopharyngeal muscle of 4.5 cm of length. The patient had a symptomatic improvement and is in good conditions five months after the operation. A 75 years old male presenting with dysphagia and ptosis. He was operated, performing a myotomy of the cricopharyngeal muscle of 3.5 cm of length. Two and a half months after operation the patient is devoid of dysphagia.
La distrofia muscular oculofaríngea (DMOF) es una enfermedad de carácter hereditario, que cursa con disfagia, ptosis palpebral y debilidad proximal de las extremidades. Para su valoración la realización de manometría y estudio radiológico contrastado pueden ser de gran utilidad a pesar de que el diagnóstico de seguridad se obtiene por el estudio genético del gen PABPN1 del cromosoma 14. La enfermedad se desarrolla al sufrir este gen pequeñas expansiones en el triplete (GCG)7-13. Presentamos dos pacientes diagnosticados genéticamente de DMOF, uno de herencia autosómica dominante y otro de herencia autosómica recesiva, ambos tratados mediante miotomía del cricofaringeo debido a la intensidad de la disfagia. En ambos casos se obtuvo una mejoría clínica evidente después de la intervención.
Assuntos
Humanos , Masculino , Feminino , Idoso , Distrofia Muscular Oculofaríngea/cirurgia , Cartilagem Cricoide/cirurgia , Distrofia Muscular Oculofaríngea/diagnóstico , Distrofia Muscular Oculofaríngea/genética , Eletromiografia , Proteína I de Ligação a Poli(A)/genéticaRESUMO
Introducción: El tratamiento del estadio avanzado de la achalasia es un tema controvertido. Cuando el esófago adopta una morfología "sigmoidea" se ha preconizado la resección esofágica como tratamiento de elección. A la luz de los resultados recientes publicados de la cirugía laparoscópica dicha conducta debe ser revisada. Material y Método: Durante un período de 11 años se estudian los pacientes en estadio avanzado, correspondientes a nuestra serie de casos operados de achalasia de esófago, tratados con esofagectomía. Resultados: Cuatro casos intervenidos con resección esofágica, plastia gástrica, y anastomosis cervical. En tres casos por vía transhiatal y el cuarto precisó toracotomía. Edad promedio de los pacientes 63 años. Tiempo medio de duración de la sintomatología clínica 37,7 años. Morbilidad: Derrame pleural en dos casos, disfonía transitoria en dos casos, una eventración. Tras un seguimiento medio de 66 meses todos están actualmente asintomáticos.
Esophageal excisión is recommended in advanced stages of achalasia, when the esophagus acquires a sigmoid morphology. We report four patients with achalasia aged 59, 60, 66 and 67 years (two males) that were treated with esophagectomy, gastroplasty and cervical anastomosis. Three were operated using a trasnhiatal approach and one required a thoracotomy. In the postoperative period, two patients had a pleural effusion, two had transient dysphonia and one had an eventration. After a follow up ranging from two to 11 years, all are asymptomatic.