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1.
Clin Oral Investig ; 28(6): 348, 2024 Jun 01.
Artigo em Inglês | MEDLINE | ID: mdl-38822934

RESUMO

OBJECTIVES: This study aims to map evidence on the relationship between hard drug use and dental wear. The scoping review is guided by the question: What is the relationship between hard drug consumption and dental wear? MATERIALS AND METHODS: Adhering to PRISMA-ScR guidelines, searches were conducted across PubMed, Embase, and four databases in March 2024. Inclusion criteria included studies investigating the association between hard drug use and dental wear, regardless of publication date or language. Data were presented through narrative exposition, tables, and a conceptual framework. RESULTS: Twenty-eight studies (four case-control, three cross-sectional, five case reports, and sixteen literature reviews) were included. Among case-control studies, 75% observed an association between drug use and dental erosion; however, no cross-sectional studies demonstrated this association. Despite questionable quality, reviews established connections between drug use and dental erosion. Studies aimed to elucidate potential causes for dental erosion. CONCLUSIONS: Analysis suggests a potential link between hard drug use and dental wear, though indirect. Factors like bruxism and reduced salivary pH may contribute to dental wear among drug users. Further investigation through primary studies exploring this relationship is necessary. CLINICAL RELEVANCE: Dentists should focus not only on clinical characteristics of dental wear but also on mediating factors such as bruxism and decreased salivary pH associated with drug use. This holistic approach allows for a deeper understanding of dental wear mechanisms, enabling targeted preventive and therapeutic interventions.


Assuntos
Desgaste dos Dentes , Humanos , Erosão Dentária/induzido quimicamente , Bruxismo , Concentração de Íons de Hidrogênio , Transtornos Relacionados ao Uso de Substâncias , Saliva/química
2.
Int J Biol Macromol ; 272(Pt 2): 132907, 2024 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-38862318

RESUMO

The aim of this study was to develop a star fruit extract (SFE) and incorporate it into aerogels based on native and phosphorylated potato starches. The phosphorylation of starch enhances its properties by incorporating phosphate groups that increase the spaces between starch molecules, resulting in a more resilient, intact aerogel with enhanced water absorption. The bioactive aerogels based on potato starch and 10, 15, and 20 % (w/w) of SFE were characterized by their morphological and thermogravimetric properties, infrared spectra, water absorption capacity, loading capacity, and antioxidant activity. Epicatechin was the major compound present in SFE. The thermal stability of SFE increased when incorporated into phosphorylated starch aerogels at a concentration of 20 %. The water absorption capacity was higher in phosphorylated starch aerogels (reaching 1577 %) than in their native counterparts (reaching 1100 %). Native starch aerogels with 15 and 20 % SFE exhibited higher antioxidant activity against hydroxyl free radicals compared to phosphorylated starch aerogels, achieving 79.9 % and 86.4 % inhibition for the hydroxyl and nitric oxide radicals, respectively. The ideal choice of freeze-dried aerogel depends on the desired effect, either to act as an antioxidant agent by releasing bioactive compounds from SFE or as a water-absorbent agent in food products.


Assuntos
Antioxidantes , Frutas , Géis , Extratos Vegetais , Solanum tuberosum , Amido , Solanum tuberosum/química , Géis/química , Extratos Vegetais/química , Extratos Vegetais/farmacologia , Amido/química , Fosforilação , Antioxidantes/química , Antioxidantes/farmacologia , Frutas/química , Averrhoa/química , Água/química
3.
Int J Biol Macromol ; 266(Pt 2): 131182, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38554898

RESUMO

Formic acid is utilized to induce esterification and chemical gelatinization in starch, particularly in the fabrication of electrospun fibers for nanomaterial production. This study investigated the impact of different concentrations (15, 20, 25, and 30 %) of cassava starch and formic acid as a solvent on the characteristics of the resultant polymeric solutions and electrospun fibers. Morphology, size distribution, thermogravimetric properties, diffraction patterns, and relative crystallinity were evaluated for the electrospun fibers. The amylose content of starch varied from 16.5 to 23.7 %, decreasing with esterification, achieving a degree of substitution of approximately 0.93. The solution-rheology exhibited elastic behavior, with viscosity increasing as starch concentration increased, hindering the fabrication of fibers at 25 and 30 % starch. Successful electrospun fibers were formed using 15 % and 20 % starch, displaying homogeneous morphologies with mean diameters of 165 nm and 301 nm, respectively. Esterification influenced thermogravimetric properties, leading to fibers with reduced degradation temperatures and mass loss compared to native starches. The electrospun fibers presented an amorphous structure, indicating a drastic reduction in relative crystallinity from 35.2 % in native starch to 8.5 % for esterified starches. This study highlights the intricate relationship between starch concentration, esterification, and solution viscosity, affecting the electrospinnability and properties of starch-polymeric solutions.


Assuntos
Formiatos , Manihot , Amido , Manihot/química , Esterificação , Formiatos/química , Amido/química , Viscosidade , Amilose/química , Reologia , Termogravimetria
4.
J Food Sci ; 89(3): 1373-1386, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38343299

RESUMO

Onion is rich in bioactive and volatile compounds with antioxidant activity. However, the pungent odor of volatile compounds (VOCs) released restricts its use. The encapsulation of red onion extract by electrospinning is an alternative to mask this odor and protect its bioactive compounds. The main objective of this study was to encapsulate red onion bulb extract (ROE) in different concentrations into zein nanofibers by electrospinning and evaluate their thermal, antioxidant, and hydrophilicity properties. The major VOC in ROE was 3(2H)-furanone, 2-hexyl-5-methyl. Incorporating ROE into the polymeric solutions increased electrical conductivity and decreased apparent viscosity, rendering nanofibers with a lower average diameter. The loading capacity of ROE on fibers was high, reaching 91.5% (10% ROE). The morphology of the nanofibers was random and continuous; however, it showed beads at the highest ROE concentration (40%). The addition of ROE to the nanofibers increased their hydrophilicity. The nanofibers' antioxidant activity against 2,2-diphenyl-1-picrylhydrazyl, nitric oxide, and hydroxyl radicals ranged from 32.5% to 57.3%. The electrospun nanofibers have the potential to protect and mask VOCs. In addition, they offer a sustainable alternative to the synthetic antioxidants commonly employed in the food and packaging industry due to their antioxidant activities.


Assuntos
Nanofibras , Zeína , Cebolas , Antioxidantes , Interações Hidrofóbicas e Hidrofílicas , Extratos Vegetais
5.
J Microencapsul ; 40(8): 567-586, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-37867427

RESUMO

Propolis has beneficial health properties attributed to of phenolic compounds. However, its application is limited. Thus, encapsulation protects the bioactive compounds of propolis from degradation, allowing their release under controlled and specific conditions and increasing their solubility. In addition to protecting flavonoids, encapsulation also minimises the undesirable characteristics of propolis, such as strong odour. We brought attention to the high antioxidant and antimicrobial activities of encapsulated propolis, and its maintained biological activity enables more uses in different areas. Encapsulated propolis can be applied in food products as an ingredient. This review describes recent advances in improving the bioactivity of propolis extracts by using encapsulation techniques, and biopolymer research strategies, focusing on applications in food products. Encapsulated propolis has a promising market perspective due to the industrial and scientific-technological advancement, the increase in the amount of research, the improvement of propolis extraction techniques, and the need of consumers for innovative products.


Assuntos
Própole , Antioxidantes/farmacologia , Fenóis , Solubilidade , Flavonoides
6.
Int J Biol Macromol ; 253(Pt 1): 126610, 2023 Dec 31.
Artigo em Inglês | MEDLINE | ID: mdl-37652330

RESUMO

This study aimed to produce oleogels based on non-germinated and germinated wheat starches with orange essential oil, apply them to replace hydrogenated vegetable fat in bread, and assess the antifungal action. The oleogels were prepared using sunflower oil, wheat starches, beeswax, water, and orange essential oil (OEO). They were evaluated to determine the volatile compounds, oil binding capacity, texture profile, storage stability for 20 days, thermogravimetric analysis, and functional groups. The breads were evaluated by their moisture content, specific volume, texture profile, volatile compounds, and microbiological contamination during 15 days of storage. The oleogels showed high storage stability, were fully intact after 20 days of storage, and had a high oil binding capacity (∼100 %). The oleogels with OEO presented increased adhesiveness and reduced hardness compared to the ones without essential oil. The oleogels with OEO based on germinated wheat starch released a high amount of volatile compounds. Substituting saturated vegetable fat with oleogels in bread formulation resulted in decreased hardness and maintained specific volume. Furthermore, incorporating OEO oleogels in the bread led to reduced growth of total mesophiles and fungi.


Assuntos
Pão , Óleos Voláteis , Pão/análise , Triticum , Verduras , Óleos Voláteis/farmacologia , Amido , Ácidos Graxos/análise
7.
Int J Biol Macromol ; 249: 126108, 2023 Sep 30.
Artigo em Inglês | MEDLINE | ID: mdl-37536415

RESUMO

This study aimed to produce water-absorbent bioactive aerogels using biodegradable raw materials, wheat starch and poly ethylene oxide (PEO), and derived from agro-industrial residues (grape skin) obtained in the wine industry. The aerogels were produced using germinated wheat starch (GWS), with and without PEO, and incorporating grape skin extract (GSE) at concentrations of 5 and 10 % (w/w). The GSE was evaluated for total and individual phenolic compounds, anthocyanins, and antioxidant activity. The starch aerogels were characterized for morphology, density, porosity, functional groups by FT-IR, relative crystallinity and diffraction pattern, water absorption capacity, antioxidant activity, and in vitro release profile of phenolic compounds in food simulant medium. The total phenolic compounds in GSE was 226.25 ± 0.01 mg equivalent of gallic acid/g GSE. The aerogels showed low density and high porosity. All aerogels demonstrated high water absorption capacity (581.4 to 997.5 %). The antioxidant activity of the aerogels increased with increasing GSE concentration and the addition of PEO. The aerogels could release GSE gradually for up to 120 days in the hydrophilic simulant medium and 240 h for the hydrophobic medium. Starch-based aerogels with GSE showed potential to be applied as exudate absorbers with antioxidant activity to develop active food packaging.


Assuntos
Antioxidantes , Vitis , Antioxidantes/farmacologia , Antioxidantes/química , Vitis/química , Antocianinas , Triticum , Amido , Espectroscopia de Infravermelho com Transformada de Fourier , Polietilenoglicóis , Água , Extratos Vegetais/química
8.
BMJ Open ; 12(12): e069329, 2022 12 22.
Artigo em Inglês | MEDLINE | ID: mdl-36549743

RESUMO

INTRODUCTION: Mental healthcare systems are challenged by how they hear and respond to what marginalised communities experience as drivers of mental distress. In Colombia, this challenge intersects with wider challenges facing post-conflict reconstruction. Our pilot study will explore the feasibility and acceptability of a participatory approach to developing community-led participatory interventions for community mental health systems strengthening and mental health improvement, in two sites in Caquetá, Colombia. METHODS AND ANALYSIS: The project is divided into three distinct phases aligned with community participatory action research cycles: diagnostic, intervention and evaluation. This allows us to use a participatory approach to design a community-led, bottom-up intervention for mental health systems strengthening and the promotion of mental health and well-being.The diagnostic phase explores local understandings of mental health, mental distress and access to mental health services from community members and health providers. The intervention stage will be guided by a participatory Theory of Change process. Community priorities will inform the development of a participatory, learning and action (PLA) informed group intervention, with a community linkage forum. The pilot of the PLA intervention will be evaluated using MRC process evaluation guidelines. ETHICS AND DISSEMINATION: This project has received ethical approval from two sources. Universidad de Los Andes (2021-1393) and the University College London (16127/005). Dissemination of findings will include academic publications, community forums, policy briefs and visual media (cartoons, pod casts and short films).


Assuntos
Serviços Comunitários de Saúde Mental , Humanos , Projetos Piloto , Colômbia , Projetos de Pesquisa , Pesquisa sobre Serviços de Saúde , Poliésteres
9.
Rev. bioét. (Impr.) ; 30(3): 644-651, jul.-set. 2022. tab
Artigo em Português | LILACS | ID: biblio-1407256

RESUMO

Resumo O Ministério da Saúde orienta que a declaração de óbito não seja emitida em casos de óbito fetal com gestação inferior a 20 semanas ou feto com peso inferior a 500 g ou estatura menor que 25 cm, acrescentando que a legislação permite a emissão da declaração em casos em que a família deseje fazer o sepultamento do feto. Nesse contexto, são poucos os casos de aborto em que a declaração é feita. Este artigo realizou revisão integrativa que responde à pergunta: os rituais de fechamento, particularmente o sepultamento (possibilitado pela emissão da declaração de óbito) em caso de morte fetal inferior a 20 semanas de idade gestacional, ajudariam no processo de luto dos pais? A literatura consultada trouxe informações favoráveis à emissão da declaração de óbito e possibilitou discussão médica, jurídica e antropológica do tema.


Abstract The Ministry of Health advises that death certificates should not be issued in cases of fetal death for a pregnancy of less than 20 weeks or fetus weighing less than 500 g or shorter than 25 cm in height; however, the legislation allows the issuance of the certificate in cases where the family wishes to bury the fetus. Given this context, abortion cases in which the certificate is issued are few. This article presents an integrative review that answers the question: would the death ceremonies, particularly the burial (made possible by the issuance of the death certificate), in case of fetal death under 20 weeks of gestational age help in the parents' mourning process? The literature consulted presented favorable information for the issuance of the death certificate and enabled a medical, legal and anthropological discussion of the theme.


Resumen El Ministerio de Salud brasileño recomienda que no se debe emitir el certificado de defunción en los casos de muerte fetal de menos de 20 semanas de gestación, feto con peso inferior a 500 g o estatura inferior a 25 cm, pero agrega que se puede permitirlo cuando la familia opta por el entierro del feto. En este contexto, el certificado se emite en pocos casos de aborto. Este artículo realizó una revisión integradora a partir de la pregunta: ¿Ayudarían en el proceso de duelo de los padres los rituales de inhumación, sobre todo el entierro (habilitado mediante la emisión de un certificado de defunción) en caso de muerte fetal con menos de 20 semanas de edad gestacional? La literatura consultada aportó con informaciones favorables a la emisión del certificado de defunción y permitió fomentar la discusión médica, jurídica y antropológica del tema.


Assuntos
Pesar , Aborto Espontâneo , Aborto , Morte Fetal
10.
Arch Oral Biol ; 136: 105374, 2022 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-35180550

RESUMO

OBJECTIVE: This living systematic review aims to integrate the morphological and tissue-based molecular characterization of oral lesions occurring in individuals infected by COVID-19 (OLICs). MATERIALS AND DESIGN: This study was performed according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. PubMed, Web of Science, Scopus, Ovid, Embase, and LILACS were searched to identify reports on OLICs with morphological and/or tissue-based molecular data. RESULTS: Four studies reporting five cases were included. Three patients were male, and the mean age of the individuals was 47.6 years. The most reported anatomical location was the palate (n = 4), whereas ulcers were the most frequent clinical presentation (n = 3). Histopathologically, all cases revealed cell vacuolization and exocytosis in the epithelial layer. In the mesenchymal layer, inflammatory cell infiltrate and thrombi/microvascular thrombosis were observed in three cases. Immunohistochemical reactions were performed in two cases. Both cases were negative for HHV-1, HHV-2, and CMV. One case revealed positivity for SARS-CoV-2 spike protein. No other molecular tests were found for the characterization of OLIC. CONCLUSIONS: The pathological characteristics of OLICs are still unspecific. However, with the ongoing COVID-19 pandemic and well-documented new cases, whether OLICs are due to coinfections or has a primary origin can be determined.


Assuntos
COVID-19 , Humanos , Masculino , Pessoa de Meia-Idade , Pandemias , SARS-CoV-2 , Glicoproteína da Espícula de Coronavírus
11.
Barbarói ; (60): 120-147, jul.-dez. 2021.
Artigo em Português | LILACS, Index Psicologia - Periódicos | ID: biblio-1361820

RESUMO

O artigo objetiva colocar em análise as referências sócio-políticas presentes na emergência do Estatuto da Criança e do Adolescente e seus efeitos nas práticas de garantia de direitos, a partir de uma experiência de participação em uma rede de serviços ao infantojuvenil. Para tanto se destaca o percurso histórico e político da formulação da lei, dando ênfase à presença do pensamento neoliberal, como organizado pelo UNICEF com seu trabalho de articulação dos movimentos e das propostas que compõem o ECA. Tendo como referência análises sobre o direito como mecanismo liberal de governo, as ideias são fundamentadas em autores clássicos como Marx e Foucault, bem como em uma literatura contemporânea brasileira que acompanha os 30 anos de execução da lei. Aponta-se para o paradoxo trazido pela execução da política de garantia de direitos sustentada em parcerias público-privadas, sob a lógica e os princípios das múltiplas faces do privado.(AU)


This article aims at analyzing the social and political references of the emergency of the Child and Adolescent Statue (CAS), as well as its effects in the guaranty of rights practices, parting from an experience of participation in a service net for infants and adolescents. We highlight the historical and political processes of the law's formulation, emphasizing the presence of the neoliberal thought, as organized by UNICEF, while it articulated the movements and proposals that compose the CAS. Understanding the right as a liberal mechanism of government, we found our ideas on classical authors as Marx and Foucault, as well as on a contemporary Brazilian literature that follows the 30 years of execution of the law. We point out to the paradox brought by the execution of a policy of rights guaranty sustained in public-private agreements, under the logic and the principles of the multiple faces of the private sense.(AU)


El artículo tiene como objetivo analizar los referentes sociopolíticos presentes en el surgimiento del Estatuto de la Niñez y la Adolescencia y sus efectos en las prácticas de garantía de derechos, a partir de una experiencia de participación en una red de servicios para la niñez y la adolescencia. Para ello, se destaca la trayectoria histórica y política de la formulación de la ley, destacando la presencia del pensamiento neoliberal, como lo organiza UNICEF con su labor de articulación de los movimientos y propuestas que integran la ECA. Basadas en análisis del derecho como mecanismo liberal de gobierno, las ideas se basan en autores clásicos como Marx y Foucault, así como en la literatura brasileña contemporánea que sigue a los 30 años de aplicación de la ley. Señala la paradoja que genera la ejecución de la política de garantía de derechos sustentada en alianzas público-privadas, bajo la lógica y los principios de las múltiples caras de lo privado.(AU)


Assuntos
Humanos , Recém-Nascido , Lactente , Pré-Escolar , Criança , Adolescente , Defesa da Criança e do Adolescente , Direitos Humanos
12.
BMJ Glob Health ; 6(10)2021 10.
Artigo em Inglês | MEDLINE | ID: mdl-34620613

RESUMO

For over 60 years, Colombia has endured violent civil conflict forcibly displacing more than 8 million people. Recent efforts have begun to explore mental health consequences of these contexts, with an emphasis on national surveys. To date few Colombian studies explore mental health and well-being from a lived experience perspective. Those that do, overlook processes that enable survival. In response to this gap, we conducted a life history study of seven internally displaced Colombian women in the Cundinamarca department, analysing 18 interview sessions and 36 hours of transcripts. A thematic network analysis, informed by Latin-American perspectives on gender and critical resilience frameworks, explored women's coping strategies in response to conflict-driven hardships related to mental well-being. Analysis illuminated that: (1) the gendered impacts of the armed conflict on women's emotional well-being work through exacerbating historical gendered violence and inequality, intensifying existing emotional health challenges, and (2) coping strategies reflect women's ability to mobilise cognitive, bodied, social, material and symbolic power and resources. Our findings highlight that the sociopolitical contexts of women's lives are inseparable from their efforts to achieve mental well-being, and the value of deep narrative and historical work to capturing the complexity of women's experiences within conflict settings. We suggest the importance of social interventions to support the mental health of women in conflict settings, in order to centre the social and political contexts faced by such marginalised groups within efforts to improve mental health.


Assuntos
Saúde Mental , Violência , Conflitos Armados , Colômbia/epidemiologia , Feminino , Humanos , Pesquisa
13.
J Food Sci ; 86(7): 2886-2897, 2021 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-34057206

RESUMO

This study aimed to produce soluble potato starch ultrafine fibers for the encapsulation of pinhão coat extract (PCE), evaluating their relative crystallinity (RC), thermal stability, antioxidant activity, antimicrobial activity against Escherichia coli and Staphylococcus aureus, as well as in vitro biological digestion. In the simulation of in vitro biological digestion, the phenolic compounds release profile was also evaluated. The ultrafine fibers were produced by electrospinning, based on a polymeric solution composed of soluble potato starch (50% w/v) and formic acid. Then, PCE was incorporated at various concentrations (0.5%, 1.0%, and 1.5%, w/w, dry basis). The endothermic event of free PCE was not observed in the ultrafine fibers, which suggests its encapsulation. The RC decreased according to the increase in PCE concentration in the ultrafine fibers. The PCE resisted thermal treatments when encapsulated into the ultrafine fibers (100 and 180°C), and the ultrafine fibers with 1% PCE presented the highest amount of preserved phenolic compounds. Regarding antioxidant activity, the free PCE presented 85% of DPPH inhibition and the ultrafine fibers had 18% inhibition, not differing among the PCE concentrations (p < 0.05). The free PCE and the ultrafine fibers with 0.5% PCE showed inhibitory effect against S. aureus and the ones with 1.5% PCE showed controlled release of phenolic compounds during the simulation of in vitro digestion. Starch ultrafine fibers showed potential to be applied in food industries due to their capacity of protecting phenolic compounds when submitted to high temperatures or gastrointestinal conditions. Nevertheless, their application depends on the end use of the product. PRACTICAL APPLICATION: The encapsulation of pinhão coat extract (PCE) in ultrafine starch fibers promotes greater preservation of phenolic compounds. Thus, it can be incorporated into different foods that are produced using the ultra-high temperature (UHT) process-at 135-145°C for 5 to 10 s, or some other equivalent time/temperature combination. Another possibility is the incorporation of ultrafine fibers in active packaging: compounds can migrate to food, improving sensory characteristics, increasing shelf life, preventing chemical and microbiological deterioration, and ensuring food safety.


Assuntos
Antibacterianos/farmacologia , Antioxidantes/farmacologia , Araucaria/química , Bactérias/efeitos dos fármacos , Digestão , Material Particulado/farmacologia , Extratos Vegetais/farmacologia , Antibacterianos/química , Antioxidantes/química , Bactérias/crescimento & desenvolvimento , Escherichia coli/efeitos dos fármacos , Escherichia coli/crescimento & desenvolvimento , Técnicas In Vitro , Material Particulado/química , Fenóis/química , Fenóis/farmacologia , Extratos Vegetais/química , Polímeros/química , Staphylococcus aureus/efeitos dos fármacos , Staphylococcus aureus/crescimento & desenvolvimento , Amido/química , Temperatura
14.
J Sci Food Agric ; 101(5): 1935-1943, 2021 Mar 30.
Artigo em Inglês | MEDLINE | ID: mdl-32914413

RESUMO

BACKGROUND: The supplementation of folic acid in food is essential in the human diet. The present study aimed to encapsulate folic acid at different concentrations (5, 10 and 15% (w/w) on a dry basis) in potato starch nanofibers produced through electrospinning. The starch/folic acid nanofibers were evaluated through morphology, Fourier transform infrared (FTIR) spectra, thermal properties, encapsulation efficiency (EE) and in vitro simulation of the human digestion. The nanofibers were also evaluated based on the folic acid content after thermal treatment (100 and 180 °C) and UVA irradiation (1 and 24 h). RESULTS: Folic acid incorporation influenced the morphology of the nanofibers to display a homogeneous and beadless morphology for nanofibers containing 15% folic acid compared with the other nanofibers (0, 5 and 10% folic acid). The mean diameter varied from 75 to 81 nm. Folic acid characteristic bands and peaks were not found in the nanofiber FTIR spectra and thermograms, respectively. The EE was 73, 87 and 95% for nanofibers with 5, 10 and 15% folic acid, respectively. CONCLUSIONS: The starch nanofibers protected folic acid from high temperature and UVA irradiation and during in vitro digestion, showing a release of the vitamin at the end of the simulation (intestinal conditions). The supplementation of folic acid in foods can be effectively achieved by its encapsulation into starch nanofibers, to ensure its protection and controlled release. © 2020 Society of Chemical Industry.


Assuntos
Composição de Medicamentos/métodos , Excipientes/química , Ácido Fólico/química , Nanofibras/química , Extratos Vegetais/química , Solanum tuberosum/química , Amido/química , Suplementos Nutricionais/análise , Digestão , Composição de Medicamentos/instrumentação , Estabilidade de Medicamentos , Ácido Fólico/metabolismo , Temperatura Alta , Humanos , Raios Ultravioleta
15.
Rev. Bras. Saúde Mater. Infant. (Online) ; 20(2): 575-586, Apr.-June 2020. tab, graf
Artigo em Inglês | Sec. Est. Saúde SP, LILACS | ID: biblio-1136433

RESUMO

Abstract Objectives: to analyze the epidemiological profile and the spatial-temporal dynamics on maternal mortality in Alagoas and its relationship with social vulnerability and income inequality. Methods: a mixed ecological study involving maternal deaths who resided in Alagoas from 1996 to 2016. Sociodemographic variables (age, race/color, education, marital status), clinical (type of obstetric cause, death by category and ICD group) were analyzed, besides the indicators (Maternal Mortality Ratio-MMR, Social Vulnerability Index and Gini Index). For the temporal analysis, we used the inflection point regression model and for the spatial analysis, the local empirical Bayesian model, Moran Global and Local statistics, and the bivariate local spatial autocorrelation analysis. Results: a total of 586 deaths (47.63/100 thousand live births) were registered, with a trend of MMR growth (APC 2.8%), with a heterogeneous distribution between health regions and cities. The profile was characterized by the predominance of young, black / mixed skin color women with low schooling. Eight cities were considered priority. There was spatial correlation with the Social Vulnerability Index and income inequality. Conclusions: identifying priority areas may contribute to planning and targeting interventions.


Resumo Objetivos: analisar o perfil epidemiológico e a dinâmica espaço-temporal da mortalidade materna em Alagoas e sua relação com a vulnerabilidade social e a desigualdade de renda. Métodos: estudo ecológico misto envolvendo os óbitos maternos de residentes em Alagoas de 1996 a 2016. Foram analisadas variáveis sociodemográficas (faixa etária, raça/cor, escolaridade, estado civil), clínicas (tipo de causa obstétrica, óbito por categoria e grupo de CID), além de indicadores (Razão de Mortalidade Materna-RMM, Índice de Vulnerabilidade Social e Índice de Gini). Para a análise temporal utilizou-se o modelo de regressão por pontos de inflexão e para a análise espacial o modelo bayesiano empírico local, a estatística de Moran Global e Local e a análise de autocorrelação espacial local bivariável. Resultados: foram registrados 586 óbitos (47,63/100 mil nascidos vivos), com tendência de crescimento da RMM (APC 2,8%), com distribuição heterogênea entre as regiões de saúde e municípios. O perfil foi caracterizado pelo predomínio de mulheres jovens, pretas/pardas e de baixa escolaridade. Oito municípios foram considerados prioritários. Houve correlação espacial com o Índice de Vulnerabilidade Social e de desigualdade de renda. Conclusões: a identificação de áreas prioritárias pode contribuir para o planejamento e direcionamento de intervenções.


Assuntos
Humanos , Feminino , Gravidez , Fatores Socioeconômicos , Perfil de Saúde , Mortalidade Materna , Mortalidade , Brasil/epidemiologia , Conglomerados Espaço-Temporais , Coeficiente de Gini/métodos
16.
J Sci Food Agric ; 100(11): 4263-4271, 2020 Aug 30.
Artigo em Inglês | MEDLINE | ID: mdl-32378215

RESUMO

BACKGROUND: Thyme essential oil (TEO) is an excellent natural substitute for synthetic compounds to maintain the quality and safety of food products. It acts as an antioxidant agent. We aimed to nanoencapsulate TEO at concentrations of 1%, 3%, and 5% (v/w, dry basis) in electrospun nanofibers made of starch (50% w/v) and formic acid (75% v/v). The rheological parameters of the fiber-forming solutions were measured, and various physical and chemical properties of the nanofibers were analyzed. RESULTS: The starch/TEO nanofibers presented homogeneous morphology. The starch nanofibers showed high encapsulation efficiency (EE, 99.1% to 99.8%), which, along with the Fourier transform infra-red (FTIR) spectrum and thermogravimetric analysis (TGA) analysis, indicate strong protection of the phenolic compounds of TEO. Nanofibers with 5% TEO retained up to 50% of the phenolic compounds after exposure to thermal treatment. The antioxidant activity against 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals of the starch/TEO nanofibers varied from 11.1% to 14.2% and the inhibition values (29.8%, P ≤ 0.05) against hydroxyl radicals were the same for free TEO and the nanofibers. CONCLUSION: Owing to these properties, electrospun starch/TEO nanofibers can be applied in food products or food packaging.


Assuntos
Antibacterianos/química , Antioxidantes/química , Nanofibras/química , Óleos Voláteis/química , Extratos Vegetais/química , Solanum tuberosum/química , Amido/química , Embalagem de Alimentos/instrumentação , Temperatura Alta , Fenóis/química , Thymus (Planta)/química
17.
J Sci Food Agric ; 100(8): 3341-3350, 2020 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-32124450

RESUMO

BACKGROUND: Yerba mate extract was encapsulated in electrospun zein fibers. Solutions were prepared with 30% (w/v) zein, and yerba mate extract was added at concentrations of 1%, 3%, and 5% (w/w). The rheology and electrical conductivity of the polymer solutions were evaluated. The extract and the fibers were characterized through an analysis of total and individual phenolic compounds, antioxidant activity, and Fourier-transform infrared (FTIR) spectra. Morphology, size distribution, and thermal stability were also evaluated. The release kinetics of zein fibers loaded with different concentrations of yerba mate were evaluated in a hydrophilic food-simulant medium (10% ethanol). RESULTS: Yerba mate extract had a total phenolic compound content of 1287.76 ± 11.55 mg of gallic acid 100 g-1 yerba mate extract. The major individual phenolic compounds obtained were chlorogenic acid and rutin, quantified by high-performance liquid chromatography and mess spectrometry (HPLC-MS). Zein fibers loaded with 5% extract exhibited higher antioxidant activity with 83.0% inhibition. The fibers with different concentrations of yerba mate displayed homogeneous morphology. Yerba mate extract encapsulated in zein fibers had greater thermal stability than the free extract. Zein fibers comprising 5% yerba mate extract, when in contact with a hydrophilic food simulant medium, showed a release of approximately 49% of extract within 50 h. CONCLUSION: Zein fibers containing yerba mate extract may be used as antioxidant releasers for food packaging. © 2020 Society of Chemical Industry.


Assuntos
Embalagem de Alimentos/instrumentação , Ilex paraguariensis/química , Extratos Vegetais/química , Polímeros/química , Zeína/química , Antioxidantes/síntese química , Antioxidantes/química , Cromatografia Líquida de Alta Pressão , Espectrometria de Massas , Fenóis/química , Polímeros/síntese química
18.
Front Psychol ; 11: 47, 2020.
Artigo em Inglês | MEDLINE | ID: mdl-32038445

RESUMO

In the context of the 2016 Peace Agreement signed between the Colombian government and the FARC-EP (Fuerzas Armadas Revolucionarias de Colombia-Ejército del Pueblo), several challenges for society and academia have emerged: (1) overcoming the gap between the rural and urban settings, which has been one of the roots of the Colombian armed conflict, and (2) training psychologists and transforming traditional educational practices, which have not been designed to fulfill community needs in a post-conflict setting. One of the strategies from academia to overcome these difficulties is to create alliances with rural communities where students learn key competences to foster a horizontal approach while actively working with the community. In the region of Caquetá, Colombia, two Territorial Spaces for Training and Reincorporation (ETCR) were created in order to provide a space for former guerrilla members' reintegration to civil society. In the ETCR Héctor Ramírez, 27 students and two faculty participated in a service-learning project (2 weeks in December 2018 and two in June 2019) where they engaged in local daily practices and social projects based on the community's prioritized needs. The aim of this study was to analyze the learning process of undergraduate psychology students in this community psychology service-learning project in the context of peacebuilding in Colombia. This study is grounded in a Participatory Action Research (PAR) approach and data collected include reflective narratives and video diaries by students before and during the course, and two focus groups after the experience. Findings suggest that students who participated in the experience are in the process of developing cultural humility, through affective understandings and the consolidation of communities of practice that include the former guerrilla members and their knowledges. Preparing psychologists to lead peacebuilding and reconciliation processes is of importance to the field because the professional competencies gained in this context surpass the professional practice as they become part of the students' abilities as citizens. The social impact is twofold: the students learn to create partnerships where purposes are co-constructed and trust-based, while the community takes the lead of their processes creating alliances with an academia that recognizes their knowledge and practices.

19.
Glob Public Health ; 15(2): 200-219, 2020 02.
Artigo em Inglês | MEDLINE | ID: mdl-31526162

RESUMO

Addressing mental health needs is a central focus of the Colombian Government's framework for socio-political reconstruction following over 60 years of conflict. Informed by WHO standards, country efforts utilise biopsychosocial models that prioritise individual psychological and psychiatric conditions. However, increasing scrutiny of the deployment of Western approaches to mental health and recovery in the global south suggests a need to explore the best route to improving mental health outcomes. Our research contributes to these debates through a qualitative study of local understandings of mental health recovery related concepts among internally displaced persons in Colombia. Analysis of focus groups with 40 internally displaced men and women established definitions for emotional distress and recovery as parallel processes linked to the fracture and rebuilding of social worlds and family life. Definitions were shaped heavily by cultural, political, economic and legal contexts of everyday survival, often linked to experiences of structural and symbolic forms of violence. We conclude that a locally informed mental health recovery model that stretches beyond individual experiences of mental ill-health to promote ideas of collective social change would be best suited to addressing mental health needs of internally displaced groups in Colombia. Implications for practice are discussed.


Assuntos
Serviços de Saúde Mental , Saúde Pública/métodos , Reabilitação/métodos , Violência/psicologia , Adulto , Colômbia , Feminino , Grupos Focais , Humanos , Masculino , Saúde Mental , Reabilitação/organização & administração
20.
Rev. MED ; 27(1): 17-27, ene.-jun. 2019. tab, graf
Artigo em Espanhol | LILACS | ID: biblio-1115216

RESUMO

Resumen: El presente artículo busca determinar la prevalência de Enterobius vermicularis y variables asociadas en población preescolar y escolar del área urbana del municipio de Chaguaní y dos jardines en Cajicá, Cundinamarca, Colombia. Para esto se realizó un estudio descriptivo, de corte transversal con toma única de muestra en la población mencionada en 44 y 42 participantes, respectivamente, cuyos padres aceptaron participar voluntariamente firmando un consentimiento para desarrollar una encuesta epidemiológica estructurada, que indagó condiciones socioeconómicas, epidemiológicas y medioambientales. El diagnóstico parasitológico se realizó con la técnica de Graham. Los participantes se distribuyeron por grupo etario: el primero estuvo conformado por 76 niños (88,4 %) con edades entre 1,5 y 8 años; el segundo, por 7 niños mayores de 8 años (8,1%), y el tercero, por 3 niños (3,5 %) sin información al respecto. La variable con significancia estadística (p≤0.05) y posible asociación protectora fue la asistencia médica trimestral y como posible riesgo el contacto con fómites. Así, se encontró que la oxiuriasis es una parasitosis prevalente en la población preescolar y escolar, asociada a condiciones higiénico-sanitarias deficientes.


Abstract: This article seeks to determine the prevalence of Enterobius vermicularis and associated variables in preschool and school population in the urban area of the municipality of Chaguaní and two kindergartens in Cajicá, Cundinamarca, Colombia. To this end, a descriptive, cross-sectional study was conducted by taking a single sample from 44 and 42 participants from such populations, respectively, whose parents agreed to participate voluntarily by signing a consent to respond to a structured epidemiological survey. This survey inquired into their socioeconomic, epidemiological, and environmental conditions. Parasitological diagnosis was made using Graham's test. Participants were distributed by age group: the first one was made up of 76 children (88.4%) between 1.5 and 8 years old; the second one, of seven children (8.1 %) over 8; and the third one, of three children (3.5 %) with no age information. A statistically significant variable (p ≤ 0.05) and possible protection factor was quarterly medical care. A possible risk factor was contact with fomites. Therefore, it was found that oxyuriasis is a prevalent form of parasitosis in preschool and school population associated with poor hygienic and sanitary conditions.


Resumo: Este artigo pretende determinar a prevalência de Enterobius vermicularis e de variáveis associadas em população pré-escolar e escolar da área urbana do município de Chaguaní e de dois jardins de infância em Cajicá, Cundinamarca, Colômbia. Para isso, foi realizado um estudo descritivo, de corte transversal, com tomada única de amostras na população em 44 e 42 participantes, respectivamente, cujos responsáveis aceitaram a participar de forma voluntária e assinaram o consentimento para responder a um questionário epidemiológico estruturado, que indagou sobre condições socioeconómicas, epidemiológicas e meio ambientais. O diagnóstico parasitológico foi realizado com a técnica Graham. Os participantes foram distribuídos por grupo de idade: o primeiro formado por 76 crianças (88,4%) entre 1,5 e 8 anos; o segundo, por 7 crianças com maios de 8 anos (8,1%), e o terceiro, por 3 crianças (3,5%) sem informação a respeito. A variável com significância estatística (p≤0,05) e possível associação protetora foi a assistência médica trimestral e, como possível risco, o contato com fômites. Assim, foi verificado que a oxiuriase é uma parasitose prevalente na população pré-escolar e escolar, associada a condições higiênico-sanitárias deficientes.


Assuntos
Humanos , Pré-Escolar , Criança , Enterobius , Oxiuríase , Parasitologia , Fatores Epidemiológicos , Fômites
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