RESUMO
BACKGROUND: Acute pulmonary edema may be induced by beta 2-mimetics used for tocolysis. CASE REPORT: A 41-year-old patient, admitted for preterm labor, presented acute pulmonary edema after parenteral tocolysis using salbutamol in combination with corticosteroid therapy to improve fetal pulmonary maturation. DISCUSSION: The pathogenic mechanism is essentially non-cardiologic. Fluid retention is probably the main cause, potentially worsened by corticosteroid administration. If detected early, pulmonary edema is usually and adequately treated by cessation of beta 2-sympathomimetic therapy, oxygen administration and diuretics. Mechanical ventilation can be required. Cardiac function must be assessed after this complication. In preterm labor, the duration of tocolysis with beta 2-sympatomimetics should be reduced.
Assuntos
Albuterol/efeitos adversos , Complicações na Gravidez/induzido quimicamente , Edema Pulmonar/induzido quimicamente , Tocolíticos/efeitos adversos , Doença Aguda , Adulto , Feminino , HumanosRESUMO
A 37 year-old man had headaches for 10 days, then a single tonic-clonic seizure and coma due to an extensive cerebral venous thrombosis. In spite of full-dose heparin treatment for 7 days, the clinical picture worsened along with increasing edema on CT-Scan. Direct thrombolytic treatment was then performed using transvenous catheterization and instillation of Urokinase (2.6 MU over 4 days). A near complete repermeabilization of the sinuses was obtained and the patient improved dramatically in a few days. The only adverse effect of Urokinase was hematuria. Based on our experience and review of the literature which includes 26 previous cases, direct thrombolytic therapy appears to be a relatively safe procedure. This treatment should be considered in a patient with extensive dural sinus thrombosis which fails to respond to heparin treatment.
Assuntos
Embolia e Trombose Intracraniana/tratamento farmacológico , Ativadores de Plasminogênio/administração & dosagem , Ativador de Plasminogênio Tipo Uroquinase/administração & dosagem , Adulto , Cateterismo Periférico , Resistência a Medicamentos , Heparina , Humanos , Injeções , Masculino , Terapia TrombolíticaRESUMO
The aim of our study was to analyse the problems caused by nosocomial infections (NI) in our intensive care unit (ICU). 239 patients admitted between January and June 1995 were included in the study. 33 episodes of nosocomial infection were diagnosed in 19 patients (7.9 percent). The overall incidence of NI was 13.9 percent. Lower respiratory tract infections were the most common (6.3 percent). Patients infected on admission to the ICU had more NI than other patients (odds ratio = 3.42, 95 percent confidence interval 3.28 - 4.52, p< 0.05). Gram negative bacteria were involved in 73.2 percent of NI. Acinetobacter baumanii and Peudomonas aeruginosa were responsible, respectively, for 22.4 percent and 25.4 percent of NI. The additional cost due to NI was 33 percent for laboratory investigations and 34 percent for antibiotics. After analysis of our results, our recommendations are a cautious use of antibiotics, more efficient diagnostic tools and particular care in preventing cross contamination of our mostly severely ill or infected patients. (AU)
Assuntos
Humanos , Infecção Hospitalar/epidemiologia , Unidades de Terapia Intensiva , Martinica/epidemiologiaRESUMO
Deep dermal burns are initially difficult to evaluate. They sometimes even undergo spontaneous healing. We present our own experience concerning the use of dermabrasion with sandpaper, a veritable alternative to early scar excision. Skin grafts are not always called for. The aesthetic results are excellent. Dermabrasion should be systematically considered for all deep dermal burns and particularly for scalding burn mechanisms or facial burns (AU)