Assuntos
Humanos , Gravidez , Feminino , Anemia Hipocrômica/epidemiologia , Complicações Hematológicas na Gravidez/epidemiologia , Anemia Hipocrômica/etiologia , Células Sanguíneas/análise , Análise Química do Sangue , Dieta , Hemoglobinas/análise , Complicações Hematológicas na Gravidez/etiologia , Trinidad e Tobago , Vitamina B 12/sangueRESUMO
At the Trinidad Nutrition Centre hemoglobin levels were determined in 555 pregnant women and a third of these were found to be less than 10 gm percent. Serum iron levels were diminished and total iron binding capacity increased wile the present saturation of TIBC was decreased in this anemic group. Serum folic acid levels were low but serum Vit. B12 levels normal. Average total protein intake was 56 gm (49 percent of animal and 51 percent of vegetable sources), representing a deficit of 26.8 percent in total protein intake. Average iron intake was 10.3 mg (20 percent of animal and 80 percent of vegetable sources), representing a 31.3 percent deficiency. In 84 percent of the patients anemia was of the hypochromic microcytic type. The authors intend to investigate further whether the high proportion of iron intake from vegetable sources plays any part in the production of anemia (AU)
Assuntos
Humanos , Gravidez , Anemia/complicações , Complicações na Gravidez , Ferro/metabolismoRESUMO
Three newer techniques for the assay of folic acid deficiency in man were evaluated and compared with the other method of employing the hematological response to physiological doses of folic acid. (1) The urinary formiminoglutamic acid (FIGLU) output before and after a histidine metabolic load correlated with clinical folic acid deficiency and with the therapeutic response to physiological doses of folic acid. (2) The plasma clearance of folic acid activity after a 15 ug/Kg B.W. doses of folic acid intravenously correlated with clinic folic acid deficiency in nutritional macrocytic anaemia and the malabsorption syndromes. It was not as useful in pregnancy and the chronic hemolytic anaemias. (3) The fasting serum folic acid activity level as measured by the L. casei microbiological assay was a useful index for clinical folic acid deficiency in macrocytic anaemia associated with malnutrition in the adult and in those with gastro-intestinal malabsorption syndromes. In the infant the range of serum levels was wide and many with clinical folic acid deficiency had levels in the normal range. In combined B12 and folic acid deficiencies, normal or elevated values for the plasma clearance and folic acid serum level, masked an underlying folic acid deficiency (AU)