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Breast Cancer Res Treat ; 15(3): 213-6, 1990 May.
Artigo em Inglês | MEDLINE | ID: mdl-2164851

RESUMO

Twenty-five patients with stage II ductal breast carcinoma followed up for ten years were studied for the presence of tissue carcinoembryonic antigen (CEA). Overall expression of CEA was 60%. The ten year survival rate was significantly higher for patients with CEA-negative tumours (70%) than for patients with CEA-positive tumours (27%), while the difference between the survival rate of patients with (30%) or without (53%) lymph node involvement did not reach significance. Among the 10 patients with lymph node involvement, CEA-negative patients had a better outcome. These results suggest that there is a correlation between the presence of tissue CEA and the prognosis of the disease, and that CEA status might possibly be more important than lymph node involvement, at least within stage II breast carcinomas.


Assuntos
Biomarcadores Tumorais/análise , Neoplasias da Mama/mortalidade , Antígeno Carcinoembrionário/análise , Carcinoma Intraductal não Infiltrante/mortalidade , Adulto , Idoso , Axila , Neoplasias da Mama/patologia , Carcinoma Intraductal não Infiltrante/patologia , Feminino , Seguimentos , Humanos , Metástase Linfática , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Taxa de Sobrevida
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