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Tissue carcinoembryonic antigen in the prognosis of early invasive breast cancer.
Hegg, R; De Souza, A Z; Pestana, C B; Cardoso de Almeida, P C.
Afiliação
  • Hegg R; Department of Gynecology, Hospital das Clínicas, University of São Paulo School of Medicine, Brasil.
Breast Cancer Res Treat ; 15(3): 213-6, 1990 May.
Article em En | MEDLINE | ID: mdl-2164851
Twenty-five patients with stage II ductal breast carcinoma followed up for ten years were studied for the presence of tissue carcinoembryonic antigen (CEA). Overall expression of CEA was 60%. The ten year survival rate was significantly higher for patients with CEA-negative tumours (70%) than for patients with CEA-positive tumours (27%), while the difference between the survival rate of patients with (30%) or without (53%) lymph node involvement did not reach significance. Among the 10 patients with lymph node involvement, CEA-negative patients had a better outcome. These results suggest that there is a correlation between the presence of tissue CEA and the prognosis of the disease, and that CEA status might possibly be more important than lymph node involvement, at least within stage II breast carcinomas.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Antígeno Carcinoembrionário / Biomarcadores Tumorais / Carcinoma Intraductal não Infiltrante Tipo de estudo: Observational_studies / Prognostic_studies Limite: Adult / Aged / Female / Humans / Middle aged Idioma: En Revista: Breast Cancer Res Treat Ano de publicação: 1990 Tipo de documento: Article País de afiliação: Brasil País de publicação: Holanda
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias da Mama / Antígeno Carcinoembrionário / Biomarcadores Tumorais / Carcinoma Intraductal não Infiltrante Tipo de estudo: Observational_studies / Prognostic_studies Limite: Adult / Aged / Female / Humans / Middle aged Idioma: En Revista: Breast Cancer Res Treat Ano de publicação: 1990 Tipo de documento: Article País de afiliação: Brasil País de publicação: Holanda