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1.
Balkan J Med Genet ; 27(1): 65-67, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-39263647

RESUMEN

Haemoglobin (Hb) Malay is variant haemoglobin with a ß++ thalassemia phenotype. The prevalence of Hb Malay in the Malaysian population was 5.5%. We describe a 58-year-old male who presented with symptomatic anaemia to the Hospital Universiti Sains Malaysia. Further history revealed that the patient had anaemia since the age of 28, and on regular follow-up at other hospital. Physical examination revealed pallor, jaundice and hepatosplenomegaly. The full blood count and peripheral blood smear showed hypochromic microcytic anaemia with anisopoikilocytosis, and many target cells. High-performance liquid chromatography results showed a ß thalassemia trait. However, the diagnosis does not alight with the patient's condition. Bone marrow aspirate was completed and showed reactive changes and erythroid hyperplasia. A molecular test was then performed for ß globin gene mutation detection using Multiplex Amplification Refractory Mutation System (M-ARMS) PCR method. This revealed the result as homozygous codon 19 mutation or Hb Malay. Therefore, in this case report we would like to highlight the laboratory approaches, the challenges faced by the usual haematological investigations and the importance role of molecular testing in the diagnosis of severe anaemia.

2.
BMC Oral Health ; 24(1): 949, 2024 Aug 16.
Artículo en Inglés | MEDLINE | ID: mdl-39152380

RESUMEN

BACKGROUND: Malaysian preschool children continue to exhibit a high prevalence of dental caries and poor oral hygiene. There is a need to gain an in-depth understanding of oral hygiene habits and design suitable interventions to improve oral hygiene in early childhood. OBJECTIVE: To cross-culturally adapt and determine the psychometric properties of the Malay-translated Parenting and Child Tooth Brushing Assessment questionnaire (M-PACTA). METHODOLOGY: This cross-sectional study involved face and content validation, and forward and back-translation of PACTA. The M-PACTA was then tested for reliability and construct validity on 150 Malaysian parents of children aged 5 to 6 years old. RESULTS: Face validity indicated that the M-PACTA items were clear and easy to understand. For content validity, some words had to be modified in accordance with the recommendations of the expert committees to make it more coherent to Malaysians. Some statements in the parental knowledge scales were modified according to the guidelines applicable in Malaysia. The content comparison of the back translation with the adapted PACTA revealed that all items were semantic and linguistically equivalent. Exploratory factor analyses of M-PACTA suggested a two-factor structure for three scales including child behaviour scale ('non-compliance' and 'avoidance behaviour'), parental attitudes ('lack of concern' and 'attitude of care'), and parental knowledge ('general tooth brushing knowledge' and 'awareness of tooth brushing care') while for the parental strategy scale, three-factor structure was extracted including 'routine positive methods', 'uncommon positive methods', and 'negative methods'. Internal consistencies for all scales were good (α > 0.9). CONCLUSION: M-PACTA did not replicate the construct of the original PACTA. Nonetheless, M-PACTA demonstrated good construct validity, internal consistency reliability, and test-retest reliability within Malaysian context.


Asunto(s)
Comparación Transcultural , Responsabilidad Parental , Psicometría , Cepillado Dental , Humanos , Malasia , Preescolar , Estudios Transversales , Niño , Femenino , Masculino , Responsabilidad Parental/psicología , Reproducibilidad de los Resultados , Padres/psicología , Encuestas y Cuestionarios , Conducta Infantil/psicología , Traducciones , Adulto , Conocimientos, Actitudes y Práctica en Salud
3.
PeerJ ; 12: e17825, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-39099660

RESUMEN

Background: The Nasal Obstruction Symptom Evaluation (NOSE) is a questionnaire to assess patients with nasal obstruction. The aim of this study was to translate and validate NOSE to the Malay version NOSE (M-NOSE). Methods: The NOSE questionnaire was translated to Malay language and back to English. Psychometric properties consisting of reliability, reproducibility, validity, responsiveness were appraised in patients with nasal obstruction due to deviated nasal septum and healthy asymptomatic controls. Results: A total of 126 participants were recruited. There was significant difference between patients and controls for all items and the total score (all p < 0.001). The correlation was moderate to strong between all items and total score (r = 0.71 to 0.8) and fair to moderate for the inter-items correlations (r= 0.31 to 0.70). Internal consistency for M-NOSE was good (α = 0.81). The test-retest for each item demonstrated no significant difference. There was significant difference of the pre- and post-operative mean for each item and total score (all p < 0.001) with good response sensitivity (effect size, d = 4.91). Conclusions: The M-NOSE has satisfactory reliability, internal consistency, reproducibility and responsiveness. It is a valid and convenient tool in the assessment of the impact and treatment outcome of nasal obstruction.


Asunto(s)
Obstrucción Nasal , Psicometría , Humanos , Obstrucción Nasal/diagnóstico , Femenino , Masculino , Reproducibilidad de los Resultados , Malasia , Adulto , Encuestas y Cuestionarios , Psicometría/métodos , Persona de Mediana Edad , Traducciones , Evaluación de Síntomas/métodos , Adulto Joven , Traducción
4.
Malays J Med Sci ; 31(3): 241-251, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38984247

RESUMEN

Background: In the world of sports, motivation is an essential concept that can affect the sporting performance of athletes and help them accomplish their goals. The coach is regarded as an important individual with the ability to significantly influence the athlete's motivation. To assess the impact of the coach-athlete relationship on motivation, the objective of this study was to evaluate the psychometric properties of the Malay version of the Coach-Athlete Relationship Questionnaire (CART-Q) for coaches and athletes. Methods: A cross-sectional survey was conducted among the coaches and athletes in Malaysia. Data were collected using a convenience sampling approach over a 6-month period. The study was carried out in two phases using two independent samples of coaches and athletes to assess the construct validity and internal consistency of the Malay version of the CART-Q. The CART-Q consisted of 11 items measuring three constructs: i) closeness (four items), ii) commitment (three items) and iii) complementarity (four items). In phase 1, the subjects consisted of 211 coaches (21 years old-65 years old) from both sexes and from individual and team sports, ranging from levels 1 to 5. In phase 2, the subjects consisted of 362 athletes (12 years old-39 years old), also from both sexes and from individual and team sports. The statistical analyses performed included confirmatory factor analysis (CFA) to validate the translated version scale, composite reliability (CR), average variance extracted (AVE) and internal consistency (Cronbach's alpha). Results: In phase 1, the sample of coaches, with 190 males (90.0%) and 21 females (10.0%), had a mean age of 38.6 (SD = 8.74) years old. The major sport type was archery (19.0%). The CFA revealed adequate fit indices with all 11 items retained (root mean square error of approximation [RMSEA] = 0.059, comparative fit index [CFI] = 0.964, Tucker and Lewis Index [TLI] = 0.950, standardised root mean square residual [SRMR] = 0.037). The CR values were closeness = 0.874, commitment = 0.566 and complementarity = 0.757. The AVE values were closeness = 0.357, commitment = 0.194 and complementarity = 0.275. The Cronbach's alpha values were closeness = 0.867, commitment = 0.553 and complementarity = 0.794. In phase 2, the sample of athletes, with 175 males (48.1%) and 189 females (51.9%), had a mean age of 20.2 (SD = 3.35) years old. The major sport type was archery (11.5%). The CFA revealed satisfactory fit indices with all 11 items retained (RMSEA = 0.092, CFI = 0.948, TLI = 0.924, SRMR =.038). The CR values were closeness = 0.893, commitment = 0.786 and complementarity = 0.949. The AVE values were closeness = 0.401, commitment = 0.253 and complementarity = 0.418. The Cronbach's alpha values were closeness = 0.900, commitment = 0.772 and complementarity = 0.900. Conclusion: Overall, the study findings supported the conclusion that the Malay version of the CART-Q has adequate psychometric properties to assess the perceptions of coaches and athletes regarding their relationship.

5.
J Patient Rep Outcomes ; 8(1): 79, 2024 Jul 25.
Artículo en Inglés | MEDLINE | ID: mdl-39052204

RESUMEN

BACKGROUND: This study aimed to translate and culturally adapt the Assessment of Quality of Life (AQoL)-6D into Malay (Malay-AQoL-6D), and assesses the instrument's acceptability, reliability, and validity among Malaysians living with chronic heart failure (HF). METHODS: The translation and cross-cultural adaptation process adhered to international guidelines. The Malay-AQoL-6D underwent content and face validity assessments via expert review, and pretesting among healthy individuals and patients with chronic conditions. Subsequent psychometric validation utilised clinico-sociodemographic data and paired AQoL-6D and EQ-5D-5L data from a health-related quality-of-life (HRQoL) survey involving Malay-speaking patients with HF, which encompassed assessments of Malay-AQoL-6D acceptability, internal consistency and test-retest reliability, as well as its construct, concurrent, convergent and divergent, and known-group validity. RESULTS: The Malay-AQoL-6D was deemed acceptable among clinicians and local patients, achieving a 90.8% completion rate among 314 patients surveyed. The instrument demonstrated strong content validity (item-level content validity index [CVI]: 0.83-1.00, average CVI: 0.98), internal consistency (Cronbach's alpha: 0.72-0.89; MacDonald's omega: 0.82-0.90, excluding the Senses dimension), and test-retest reliability (average intraclass correlation coefficients: 0.79-0.95). Confirmatory factor analysis confirmed the instrument's two-level, six-factor structure (Satorra-Bentler [SB]-scaled χ2(df: 164): 283.67, p-value < 0.001; root mean square error of approximation [RMSEA]: 0.051; comparative fix index [CFI]: 0.945, Tucker-Lewis index [TLI]: 0.937; standardised root mean-squared error [SRMR]: 0.058). The Malay-AQoL-6D's concurrent validity was evident through its good agreement with EQ-5D-5L. Multiple hypothesis tests further affirmed its construct and known-group validity. The Malay-AQoL-6D's psychometric properties remained consistent across different missing data techniques. CONCLUSION: The findings suggest that Malay-AQoL-6D could be a culturally acceptable, reliable, and valid HRQoL measure for quantifying HRQoL among the local HF population. Future studies are necessary to further validate the instrument against other measures and confirm the instrument's test-retest reliability and responsiveness, which are possible with the availability of the Malay-AQoL-6D.


Asunto(s)
Comparación Transcultural , Insuficiencia Cardíaca , Psicometría , Calidad de Vida , Humanos , Calidad de Vida/psicología , Psicometría/instrumentación , Psicometría/métodos , Psicometría/normas , Malasia , Masculino , Femenino , Insuficiencia Cardíaca/psicología , Insuficiencia Cardíaca/etnología , Reproducibilidad de los Resultados , Persona de Mediana Edad , Anciano , Enfermedad Crónica , Encuestas y Cuestionarios , Traducciones , Adulto , Pueblos del Sudeste Asiático
6.
Leg Med (Tokyo) ; 70: 102463, 2024 Sep.
Artículo en Inglés | MEDLINE | ID: mdl-38823287

RESUMEN

Closely linked groups of markers on the X chromosome are very useful for testing complex kinship relationships involving X-STR transmission. The Argus X-12 kit, a unique commercially available kit, can obtain haplotypes of 4 linkage groups (LGs) consisting of 3 markers. Although many population data have been reported for forensic purposes, differences in discrimination ability exist between LG1 and LG2, 3, and 4 in East Asian populations, and the data of this kit would become more useful if the discrimination ability of the latter groups were increased. Therefore, for matches found using this kit for some linkage group data, then to increase the identification ability, we additionally introduced 13 X-STR loci and established a method allowing comparison using data from 25 loci. The 13X-STRs add two locus data to each of LG2, 3, and 4, and also add two closely linked group (CLG) data between LG2 and 3 and LG3 and 4 in one multiplex PCR. Assessment of this method for a Malay population for which data by Argus X-12 had already been reported showed that the frequencies of distinct haplotypes in LG2, 3, and 4 were increased by 33.0-42.6 %, and frequencies of unique haplotypes increased by 45.4-59.2 %. The respective haplotype diversity values of the additional 3-locus and 4-locus CLGs were 0.9838 and 0.9939, which helps to improve discriminatory power and to predict recombination locations on the X chromosome. Although we have been testing these loci with Japanese subjects, this system would also be useful for the Malay population.


Asunto(s)
Cromosomas Humanos X , Genética de Población , Haplotipos , Repeticiones de Microsatélite , Reacción en Cadena de la Polimerasa Multiplex , Humanos , Reacción en Cadena de la Polimerasa Multiplex/métodos , Cromosomas Humanos X/genética , Malasia , Genética de Población/métodos , Repeticiones de Microsatélite/genética , Masculino , Pueblo Asiatico/genética , Genética Forense/métodos , Dermatoglifia del ADN/métodos , Ligamiento Genético
7.
Clin Linguist Phon ; : 1-22, 2024 Jun 09.
Artículo en Inglés | MEDLINE | ID: mdl-38853461

RESUMEN

Research on narrative skills in the Malay language is scarce for both typically developing (TD) and children with Developmental Language Disorders (DLD). This study examines the differences in narrative abilities of Malay-speaking school-age children with and without DLD. Fifteen Malay-speaking TD children and 15 children with DLD told four stories elicited using the Multilingual Assessment Instrument for Narrative (MAIN). Group comparisons were conducted in narrative production (story retelling and story generation) as well as in comprehension. We also examined the differences in both groups' story complexity (e.g. the combination of goals (G), attempts (A) and outcomes (O)). General microstructure features such as the total number of words (TNW), total number of sentences (TNS) and total number of different words (NDW) were also investigated. TD children outperformed children with DLD in both narrative production and comprehension performances. TD children constructed a higher combination of G, A, and O components than children with DLD. Children with DLD frequently produced G, A, and O in isolation in comparison to TD children. In language productivity and lexical complexity, TD children had a significantly higher frequency in TNW and NDW than children with DLD, resulting in longer narratives and higher uses of different words than children with DLD. Distinct differences are found in the narrative profile of TD children and children with DLD. The results are relatively consistent with the findings of similar studies that utilised and adapted the MAIN in other languages. Clinical implications and recommendations are discussed.

8.
Clin Optom (Auckl) ; 16: 107-114, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38596476

RESUMEN

Introduction: Corneal characteristics are unique to each eye and can vary among different levels of refractive errors. However, minimal data are available in the literature on corneal characteristics in myopic Malay school children including the difference between the low myopic group and the moderate myopic group. Therefore, this study aims to determine the corneal characteristics of myopic Malay school children and their associations with axial length. Methods: A total of eighty-four data samples were extracted from forty-two myopic Malay school children. Measurements of the central corneal thickness (CCT), corneal curvature, corneal diameter, and axial length were measured using Lenstar LS900, a non-contact optical biometer. Data were later stratified by the spherical equivalent refraction (SER) into a low myopic group and a moderate myopic group, and paired t-test were employed to determine the differences in the corneal characteristics between these two groups. Univariate and multivariate linear regressions were performed to identify factors that are significantly associated with axial length. Results: There was no significant difference in the CCT, corneal curvature and corneal diameter between the low myopic group and the moderate myopic group (t82=0.015, P=0.99), (t82=-0.802, P=0.43) and (t82=-0.575, P=0.57), respectively. Pearson univariate correlation analysis found that axial length significantly correlated with corneal curvature (r=-0.765, P<0.001) and corneal diameter (r=0.614, P<0.001) but no significant correlation found with CCT (r=0.046, P=0.68). Multiple regression analysis showed that axial length was significantly associated with a flatter corneal curvature (P<0.001), older age (P<0.001) and larger corneal diameter (P=0.02). Conclusion: This study reported the corneal characteristics in myopic Malay school children and its associations with axial length. Results of this study can serve as a reference value for the myopic Malay schoolchild population.

10.
Mar Pollut Bull ; 203: 116418, 2024 Jun.
Artículo en Inglés | MEDLINE | ID: mdl-38677218

RESUMEN

An equilibrium partitioning approach (EqPA) was employed to evaluate the metal toxicity and define sediment quality guidelines (SQGs) for arsenic (As), cadmium (Cd), chromium (Cr), copper (Cu), nickel (Ni), lead (Pb), zinc (Zn), and mercury (Hg) in the cockle cultivated areas located in Bandon Bay, Thailand. An assessment of metal toxicity using the [∑SEM]-[AVS] and [∑SEM]-[AVS]/foc models indicated no adverse effect on benthic organisms. The normalized total metal concentrations in this area were below the established SQG values for As, Cd, Cu, Ni, Pb, Zn, and Hg, namely respectively 21.3, 0.8, 84.6, 36.0, 34.6, 440.9 mg/kg dry weight, and 49.3 µg/kg dry weight on sand and calcium carbonate free with 1 % total organic carbon basis, suggesting low metal toxicity. This study provides locality adapted SQG values for supporting sediment quality management specifically in Bandon Bay, potentially serving as a model for other coastal areas.


Asunto(s)
Bahías , Monitoreo del Ambiente , Sedimentos Geológicos , Metales , Contaminantes Químicos del Agua , Tailandia , Sedimentos Geológicos/química , Contaminantes Químicos del Agua/análisis , Contaminantes Químicos del Agua/toxicidad , Metales/análisis , Metales/toxicidad , Animales , Estuarios , Metales Pesados/análisis , Metales Pesados/toxicidad
11.
Digit Health ; 10: 20552076241242795, 2024.
Artículo en Inglés | MEDLINE | ID: mdl-38571876

RESUMEN

Objective: This study aimed to determine the usability of the EMPOWER-SUSTAIN Self-Management Mobile App© and evaluate the factors associated with its usability among patients with cardiovascular risk factors in primary care. Methodology: This was a cross-sectional study, conducted among patients aged ≥ 18 years with cardiovascular risk factors attending a university primary care clinic. Patients were given the app to use for at least three months. Those who fulfilled the eligibility criteria were recruited. Data gathered were on sociodemographic, clinical characteristics, self-management support by doctors, utilisation of the app at home and social support in using the app. The previously translated and validated Malay version of the mHealth App Usability Questionnaire was used to measure usability. The mean usability score was calculated and linear regressions analysis was conducted to determine the factors associated with the usability of the app. Results: A total of 247 patients with at least one cardiovascular risk factor(s) were recruited. The mean age was 60.2 (±8.2). The majority were Malays (86.2%) and half of them were males (52.2%). The total mean (±SD) usability score was 5.26 (±0.67) indicating a high usability of the app. Usability of the app declined with increasing age in the simple linear regressions analysis. The multiple linear regressions yielded that being Malay (b = 0.31, 95% CI 0.08,0.54), using the app at home to understand their medications (b = 0.33, 95% CI 0.12,0.53) and having social support from family members and friends (b = 0.28, 95% CI 0.07,0.49) were significantly associated with higher usability of the app. Conclusion: The usability of the EMPOWER-SUSTAIN Self-Management Mobile App© was high among patients with cardiovascular risk factors in our primary care clinic. This finding supports the widespread use of this app among our patients. Involvement of family members and friends should be encouraged to improve the usability of the app.

12.
Heliyon ; 10(5): e26713, 2024 Mar 15.
Artículo en Inglés | MEDLINE | ID: mdl-38439829

RESUMEN

Background: The HLA-B alleles have been used as a marker to predict drug-induced adverse reactions and as a major contributor to hypersensitivity reactions. We examined the feasibility of HLA-B alleles as pharmacogenomic markers of drug-induced hypersensitivity in an Indonesian Malay Ethnic. Methods: Fifty-eight Indonesian individuals of Malay ethnicity were enrolled in this study. HLA-B alleles were determined using reverse sequence-specific oligonucleotide probe coupled with xMAP technology. Results: HLA-B*15:02 (15.52%), HLA-B*35:05 (9.48%), and HLA-B*07:05 (7.76%) were frequent alleles in the Indonesian Malay ethnic populations. We discovered at least eight pharmacogenomics markers of drug-induced hypersensitivity: HLA-B*15:02, HLA-B*15:21, HLA-B*13:01, HLA-B*35:05, HLA-B*38:02, HLA-B*51:01, HLA-B*57:01, and HLA-B*58:01. HLA-B*15:02 was in the same serotype group with HLA-B*15:21, which is a B-75 serotype associated with genetic predisposition for carbamazepine-induced Stevens-Johnson syndrome and toxic epidermal necrolysis. The Indonesian population, represented by Malay, Javanese, and Sundanese ethnicities, was similar to South East Asian, Han Chinese, and Taiwanese populations based on HLA-B*15:02 frequency as the most common allele found in Malay ethnics. Conclusion: We provided valuable information on the frequency of drug hypersensitivity-associated HLA-B alleles in Indonesian Malay ethnic population, which can improve treatment safety.

13.
Cureus ; 16(2): e53890, 2024 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-38465057

RESUMEN

BACKGROUND AND OBJECTIVES: The study aims to investigate the normal reference values for optic nerve head (ONH) and retinal nerve fiber layer (RNFL) parameters in emmetropic Malay children, utilizing measurements obtained through Cirrus SD-OCT (Carl Zeiss Meditec, Dublin, CA). METHODOLOGY: A cross-sectional study was conducted on 95 Malay children, aged between seven and 17 years, with no ocular abnormalities. It was held at Hospital Universiti Sains Malaysia, Malaysia, from January 2014 to December 2015. All children underwent a full ocular examination, including refraction and calculation of axial length. ONH and retinal nerve fiber layer thickness (RNFLT) parameters were measured using the Cirrus SD-OCT machine. One eye of each subject was selected randomly for study. The associations between the parameters and the effect of age, gender, axial length, and spherical equivalent (SE) on the measurements were statistically validated. RESULTS: Ninety-five children were involved in the study, with 65 females (68.4%) and 30 males (31.6%). The mean age was 10.6 (2.82) years, the mean intraocular pressure (IOP) was 14.8 (2.81) mmHg, the mean SE-refraction was 0.12 (0.28) diopters, and the mean axial length was 23.03 (0.76) mm. The mean disc area, rim area, and cup volume were 2.32 (0.40) mm2, 1.53 (0.33) mm2, and 0.204 (0.16) mm3, respectively. The average cup-to-disc ratio (SD) (CDR) and the vertical CDR were 0.55 (0.13) and 0.50 (0.14). Mean (SD) RNFLT was 102.08 (11.08) µm for all patients. There was a strong positive correlation between the average, superior, and inferior RNFLT with the optical disc area. The rim area and the average, superior, inferior, and nasal RNFLT also showed a significant correlation. The inferior RNFLT was negatively correlated with the average CDR. There was also a major influence of gender on the disc area. There were no major age, axial length, and SE influences on the measurements. CONCLUSIONS: This study provided normative information for ONH and RNFLT parameters in emmetropic Malay children. It was observed that emmetropic Malay males exhibited a significantly larger optical disc area. The increase in RNFLT is correlated with a significant increase in disc and rim areas.

14.
Phonetica ; 81(3): 321-349, 2024 Jun 25.
Artículo en Inglés | MEDLINE | ID: mdl-38522003

RESUMEN

This study investigates the variation in phrase-final f0 movements found in dyadic unscripted conversations in Papuan Malay, an Eastern Indonesian language. This is done by a novel combination of exploratory and confirmatory classification techniques. In particular, this study investigates the linguistic factors that potentially drive f0 contour variation in phrase-final words produced in a naturalistic interactive dialogue task. To this end, a cluster analysis, manual labelling and random forest analysis are carried out to reveal the main sources of contour variation. These are: taking conversational interaction into account; turn transition, topic continuation, information structure (givenness and contrast), and context-independent properties of words such as word class, syllable structure, voicing and intrinsic f0. Results indicate that contour variation in Papuan Malay, in particular f0 direction and target level, is best explained by turn transitions between speakers, corroborating similar findings for related languages. The applied methods provide opportunities to further lower the threshold of incorporating intonation and prosody in the early stages of language documentation.


Asunto(s)
Lenguaje , Fonética , Humanos , Femenino , Masculino , Indonesia , Acústica del Lenguaje , Adulto , Lingüística , Medición de la Producción del Habla
15.
Artículo en Inglés | MEDLINE | ID: mdl-38451114

RESUMEN

BACKGROUND: Parkinson's disease (PD) has an impact on speech production, manifesting in various ways including alterations in voice quality, challenges in articulating sounds and a decrease in speech rate. Numerous investigations have been conducted to ascertain the oral-diadochokinesis (O-DDK) rate in individuals with PD. However, the existing literature lacks exploration of such O-DDK rates in Malaysia and does not provide consistent evidence regarding the advantage of real-word repetition. AIMS: To explore the effect of gender, stimuli type and PD status and their interactions on the O-DDK rates among Malaysian-Malay speakers. METHODS & PROCEDURES: O-DDK performance of 62 participants (29 individuals with PD and 33 healthy elderly) using a non-word ('pataka'), a Malay real-word ('patahkan') and an English real-word ('buttercake') was audio recorded. The number of syllables produced in 8 s was counted. A hierarchical linear modelling was performed to investigate the effects of stimuli type (non-word, Malay real-word, English real-word), PD status (yes, no), gender (male, female) and their interactions on the O-DDK rate. The model accounted for participants' age as well as the nesting of repeated measurements within participants, thereby providing unbiased estimates of the effects. OUTCOMES & RESULTS: The stimuli effect was significant (p < 0.0001). Malay real-word showed the lowest O-DDK rate (5.03 ± 0.11 syllables/s), followed by English real-word (5.25 ± 0.11 syllables/s) and non-word (5.42 ± 0.11 syllables/s). Individuals with PD showed a significantly lower O-DDK rate compared to healthy elderly (4.73 ± 0.15 syllables/s vs. 5.74 ± 0.14 syllables/s, adjusted p < 0.001). A subsequent analysis indicated that the O-DDK rate declined in a quadratic pattern. However, neither gender nor age effects were observed. Additionally, no significant two-way interactions were found between stimuli type, PD status and gender (all p > 0.05). Therefore, the choice of stimuli type has no or only limited effect considering the use of O-DDK tests in clinical practice for diagnostic purposes. CONCLUSIONS & IMPLICATIONS: The observed slowness in O-DDK among individuals with PD can be attributed to the impact of the movement disorder, specifically bradykinesia, on the physiological aspects of speech production. Speech-language pathologists can gain insights into the impact of PD on speech production and tailor appropriate intervention strategies to address the specific needs of individuals with PD according to disease stages. WHAT THIS PAPER ADDS: What is already known on this subject The observed slowness in O-DDK rates among individuals with PD may stem from the movement disorder's effects on the physiological aspects of speech production, particularly bradykinesia. However, there is a lack of consistent evidence regarding the influence of real-word repetition and how O-DDK rates vary across different PD stages. What this study adds to existing knowledge The O-DDK rates decline in a quadratic pattern as the PD progresses. The research provides insights into the advantage of real-word repetition in assessing O-DDK rates, with Malay real-word showing the lowest O-DDK rate, followed by English real-word and non-word. What are the potential or actual clinical implications of this work? Speech-language pathologists can better understand the evolving nature of speech motor impairments as PD progresses. This insight enables them to design targeted intervention strategies that are sensitive to the specific needs and challenges associated with each PD stage. This finding can guide clinicians in selecting appropriate assessment tools for evaluating speech motor function in PD patients.

16.
Q J Exp Psychol (Hove) ; : 17470218241234668, 2024 Mar 21.
Artículo en Inglés | MEDLINE | ID: mdl-38356189

RESUMEN

Theories of word processing propose that readers are sensitive to statistical co-occurrences between spelling and meaning. Orthographic-semantic consistency (OSC) measures provide a continuous estimate of the statistical regularities between spelling and meaning. Here we examined Malay, an Austronesian language that is agglutinative. In Malay, stems are often repeated in other words that share a related meaning (e.g., sunyi/quiet; ke-sunyi-an/silence; makan/eat; makan-an/foods). The first goal was to expand an existing large Malay database by computing OSC estimates for 2,287 monomorphemic words. The second goal was to explore the impact of root family size and OSC on lexical decision latencies for monomorphemic words. Decision latencies were collected for 1,280 Malay words of various morphological structures. Of these, data from 1,000 monomorphemic words were analysed in a series of generalised additive mixed models (GAMMs). Root family size and OSC were significant predictors of decision latencies, particularly for lower frequency words. We found a facilitative effect of root family size and OSC. Furthermore, we observed an interaction between root family size and OSC in that an effect of OSC was only apparent in words with larger root families. This interaction has not yet been explored in English but has the potential to be a new benchmark effect to test distributional models of word processing.

17.
BMC Public Health ; 24(1): 173, 2024 01 13.
Artículo en Inglés | MEDLINE | ID: mdl-38218795

RESUMEN

OBJECTIVE: The Illness Cognition Questionnaire (ICQ) was translated from its original English version to the Malay version for this research, adapted the Malay language version of the ICQ (ICQ-M) for use in cancer patients, and assessed the internal consistency, content, face, construct, convergent, discriminant and concurrent validity of the ICQ-M among a cohort of cancer patients with mixed cancer types in Malaysia. METHOD: Initially, the ICQ was translated into Malay and back-translated, and its content and face validity were evaluated. Then, 346 cancer patients with various cancer types received the ICQ-M, and its internal consistency, convergent, discriminant, construct, and concurrent validity were evaluated. RESULTS: The ICQ-M and its domains had acceptable internal consistency with Cronbach's α ranging from 0.742 to 0.927. Construct validity assessment demonstrated that the ICQ-M consists of 17 items designated in two domains with good convergent and discriminant validity. The ICQ-M and its domains also had moderate correlations with the Acceptance and Action Questionnaire II, which denotes that the ICQ-M had acceptable concurrent validity. CONCLUSION: The ICQ-M had good psychometric properties and is now available to measure the illness cognition of cancer patients in Malaysia.


Asunto(s)
Lenguaje , Neoplasias , Humanos , Malasia , Psicometría , Encuestas y Cuestionarios , Reproducibilidad de los Resultados , Cognición
18.
Tob Induc Dis ; 222024.
Artículo en Inglés | MEDLINE | ID: mdl-38268983

RESUMEN

INTRODUCTION: Perception is an essential factor influencing smoking among adolescents. Thus, a valid tool for measuring perception is a requisite in smoking studies. This study further establishes the validity and reliability of a Malay language version of the Perception Towards Smoking Questionnaire (BM-PTSQ) for assessing the perception of smoking among secondary school-going adolescents in Malaysia. METHODS: We administered the BM-PTSQ to 669 secondary school students selected through multistage sampling; 60% of respondents were male (n=398), and 69.9% (n=463) were from rural areas. Respondents were aged 13-16 years, 36.4% (n=241) were 13 years, 40.0% (n=265) were 14 years, and 23.6% (n=156) were 16 years old. We used parallel and exploratory factor analysis (EFA) to determine the domains of the questionnaire. In addition, we also employed EFA, confirmatory factor analyses (CFA), and Cronbach's alpha to evaluate the construct validity and reliability of the BM-PTSQ. RESULTS: EFA and parallel analysis identified two domains in the BM-PTSQ that accounted for 62.9% of the observed variance, and CFA confirmed the two-domain structure. The two domains' internal consistency scores ranged from 0.702 to 0.80, which suggested adequate reliability. CONCLUSIONS: The BM-PTSQ has acceptable psychometric validity and is appropriate for assessing smoking perception and intention among Malaysian secondary school-aged youth. Researchers should further evaluate this tool's applicability in a more sociodemographically diverse population.

19.
Data Brief ; 52: 110034, 2024 Feb.
Artículo en Inglés | MEDLINE | ID: mdl-38282916

RESUMEN

Low-resource languages, like Malay, face the threat of extinction when linguistic resources become scarce. This paper addresses the scarcity issue by contributing to the inventory of low-resource languages, specifically focusing on Malay-English, known as Manglish. Manglish speakers are primarily located in Malaysia, Indonesia, Brunei, and Singapore. As global adoption of second languages and social media usage increases, language code-switching, such as Spanglish and Chinglish, becomes more prevalent. In the case of Malay-English, this phenomenon is termed Manglish. To enhance the status of the Malay language and its transition out of the low-resource category, this unique text corpus, with binary annotations for biological gender and anonymized author identities is presented. This bi-annotated dataset offers valuable applications for various fields, including the investigation of cyberbullying, combating gender bias, and providing targeted recommendations for gender-specific products. This corpus can be used with either of the annotations or their composite. The dataset comprises of posts from 50 Malaysian public figures, equally split between biological males and females. The dataset contains a total of 709,012 raw X posts (formerly Twitter), with a relatively balanced distribution of 53.72% from biological female authors and 46.28% from biological male authors. Twitter API was used to scrape the posts. After pre-processing, the total posts reduced to 650,409 posts, widening the gap between the genders with the 56.88% for biological female and 43.12% for biological male. This dataset is a valuable resource for researchers in the field of Malay-English code-switching Natural Language Processing (NLP) and can be used to train or enhance existing and future Manglish language transformers.

20.
Int J Paediatr Dent ; 34(3): 267-276, 2024 May.
Artículo en Inglés | MEDLINE | ID: mdl-37985445

RESUMEN

BACKGROUND: The Abeer Children Dental Anxiety Scale (ACDAS) source language was developed and validated in an English-speaking country in the UK to measure dental anxiety among children. The ACDAS also included the child's cognitive assessment, as well as feedback from the parent or the legal guardian and a dental health professional (DHP). This is the first study to validate the application of the ACDAS in Malay or Bahasa Melayu for children aged 6-16 years. AIM: To assess the Malay-translated version of the ACDAS, postadaptation into the local context and validation by the content and construct experts. DESIGN: The English ACDAS was translated into Malay first through forward translation and then through backward translation. The prefinal translated version of the instrument was designed, with the participation of 61 children and 61 parents or legal guardians. Subsequently, a final cross-cultural adaptation of the instrument was then made for another group of participants and evaluated for validity and test-retest reliability among 144 children and 144 parents or legal guardians participating in the self-report feedback process at the Paediatric Dental Clinic, Faculty of Dentistry, Universiti Malaya, Kuala Lumpur, Malaysia. The cross-cultural adaptation of the instrument considered translating to Malaysian national language and adapting to its culture. RESULTS: The Malay-translated ACDAS consisted of 19 items. The translated version of Malaysian-ACDAS (MY-ACDAS) achieved an acceptable agreement between six expert committee members with an internal consistency (Cronbach's alpha value, αconsistency) of 0.839. The test-retest reliability results of all participants support semantic and conceptual equivalence as an accepted construct validity between the children, parents and DHPs across the multicultural Malaysian population. CONCLUSION: The MY-ACDAS is a valid and reliable scale for measuring dental anxiety among Malaysian children.


Asunto(s)
Comparación Transcultural , Ansiedad al Tratamiento Odontológico , Humanos , Niño , Autoinforme , Encuestas y Cuestionarios , Ansiedad al Tratamiento Odontológico/diagnóstico , Reproducibilidad de los Resultados , Calidad de Vida/psicología
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