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This research introduces a methodology for data-driven regression modeling of components exhibiting nonlinear characteristics, utilizing the sparse identification of nonlinear dynamics (SINDy) method. The SINDy method is extended to formulate regression models for interconnecting components with nonlinear traits, yielding governing equations with physically interpretable solutions. The proposed methodology focuses on extracting a model that balances accuracy and sparsity among various regression models. In this process, a comprehensive model was generated using linear term weights and an error histogram. The applicability of the proposed approach is demonstrated through a case study involving a sponge gasket with nonlinear characteristics. By contrasting the predictive model with experimental responses, the reliability of the methodology is verified. The results highlight that the regression model, based on the proposed technique, can effectively establish an accurate dynamical system model, accounting for realistic conditions.

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Gaskets and seals are essential components in the operation of proton exchange membrane (PEM) fuel cells and are required for keeping hydrogen and air/oxygen within their individual compartments. The durability of these gaskets and seals is necessary, as it influences not only the lifespan but also the electrochemical efficiency of the PEM fuel cell. In this study, the cause of silicon leaching from silicone gaskets under simulated fuel cell conditions was investigated. Additionally, to reduce silicon leaching, the silica surface was treated with methyltrimethoxysilane, vinyltriethoxysilane, and (3,3,3-trifluoropropyl)trimethoxysilane. Changes in the silica surface chemistry were investigated by scanning electron microscopy, energy dispersive X-ray spectroscopy, thermogravimetric analysis, elemental analysis, X-ray photoelectron spectroscopy, and Fourier transform infrared spectroscopy. Inductively coupled plasma-optical emission spectroscopy analysis revealed that surface-treated silica was highly effective in reducing silicon leaching.

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Objective:To investigate the safety and utility of using polyester spacers in conventional pancreatico-enteric anastomosis in pancreaticoduodenectomy to achieve prevention of postoperative pancreatic fistula.Methods:The clinical data of 82 patients with pancreaticoduodenectomy completed by the same physician in Anyang People's Hospital from August 2018 to August 2023 were retrospectively analyzed, including 52 males and 30 females, aged (62.21±9.75) years. They were divided into two groups, test group ( n=40) and control group ( n=42) according to whether polyester spacers were used in pancreatico-intestinal anastomosis, the perioperative data of the two groups were compared, and Logistic analysis was used to analyze the risk factors affecting postoperative pancreatic fistula. Results:There was no statistically significant difference between the two groups in terms of biliary fistula, intestinal fistula, abdominal infection, abdominal bleeding, and postoperative mortality rate (all P>0.05). The incidence of postoperative pancreatic fistula in the test group was 20.0% (8/40) which was lower than that in the control group 45.2% (19/42), and the difference was statistically significant ( P=0.015). Soft pancreas texture ( OR=16.595, 95% CI: 1.891~145.657) was an independent risk factor for postoperative pancreatic fistula, while improved pancreatic enterostomy with polyester spacers ( OR=0.332, 95% CI: 0.114~0.969) could reduce the risk of postoperative pancreatic fistula. Conclusion:Use of polyester spacers to reinforce the pancreatico-enteric anastomosis during pancreaticoduodenectomy reduces the incidence of postoperative pancreatic fistulae with good safety and practicality.

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The article presents the influence of important design parameters of a spiral gasket on axial stiffness and leakage level. These parameters were the angle of inclination of the central part of the spiral section, the length of the vertical part of the spiral section, and the degree of densification of the material filling the metal coils. The scope of work was divided into two stages. In the first, experimental tests were conducted to determine the stiffness and tightness of a standard spiral gasket at two extreme levels of densification of the filler material, and the elastic-plastic properties of expanded graphite, which is the filler material of the metal spirals, were determined. In the second stage, multivariate numerical calculations were carried out to determine the axial stiffness of the gasket and to evaluate the distribution of contact pressure on the sealing surface. A novel aspect of the work is the proposal of a mathematical model to estimate the averaged value of the modulus of elasticity of the filler material as a function of the degree of densification and the execution of an experimental plan that significantly allowed the adoption of a limited number of analysed model variants used in the numerical calculations.

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OBJECTIVE: Risk factors for a postoperative cerebrospinal fluid leak (CSF) after surgery include an intraoperative high flow of CSF, elevated body mass index, defect size, and defect site. In our prior series, a high postoperative CSF leak rate for tumors of the central skull base (planum, sella, and clivus) appeared to be due to graft migration. We changed our closure technique from a single layer of collagen +/- fat graft to a novel graft, termed a "Bow tie" (a tri-layer fat graft with two pieces of collagen matrix), and report our results in this study. METHODS: Retrospective temporal epoch study of a single otolaryngologist's experience of closing skull base defects in our skull base center from 2005 to 2017. RESULTS: One hundred and forty-nine patients met inclusion criteria in two time periods, pre- and post-introduction of the Bow tie technique. In epoch I, from 2005 to 2013, 79 patients had reconstruction with a single layer of dural graft (25 had additional free fat graft). In epoch II, from 2014 to 2017, 70 patients had reconstruction with the Bow tie. RESULTS: CSF leak rates were 8.7% overall: 15.2% in epoch I and 1.4% in epoch II (p = 0.01). After controlling the procedure, defects with a size greater than 2 cm had a 5.7 greater likelihood of failure. Epoch II had a lower incidence of major complications. CONCLUSION: Using a single surgeon's experience, the multilayer Bow tie has a significant reduction in postoperative CSF leak and associated major complications for defects of the central skull base. LEVEL OF EVIDENCE: 3 Laryngoscope, 133:1568-1575, 2023.

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Once installed, underground concrete pipes with rubber gaskets might be exposed to contaminated soil and groundwater. A pipe material monitoring capsule (PMMC) has been developed to evaluate volatile organic compounds (VOCs) breaking through three types of pipe gaskets; Neoprene, Buna-N, and Viton. The PMMCs were deployed in three contaminated sites: two with gasoline and one with chlorinated solvent (CS). A 3-D field-domain numerical model has been developed for each site to calibrate equivalent hydraulic parameters of each gasket material (ke, D) against benzene and PCE diffusion. The calibrated parameters were then used to compute the concentrations as well as rate of breakthrough of the two study contaminants. A protocol was developed for installing/retrieval of PMMCs to monitor PCE and benzene mass breaking through the gasket material with time. Employing PMMC, benzene concentrations breaking through the Neoprene and Buna-N after 4 months were approximately 70% and 60% respectively of the monitoring wells concentration. The corresponding value for PCE breakthrough after 4 months was 60% for both the Neoprene and Buna-N. Both gasket materials of Neoprene and Buna-N yielded similar performances, including higher rate of contaminant breakthrough compared to Viton. A nonlinear relationship of mass breaking through the gaskets of benzene and PCE with time was discerned from the modeling and field data.

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Care for the natural environment, which can be observed in the tightening of emission standards, has enforced the search for new fuels, especially renewable sources of natural origin. The article presents the results of theoretical and experimental considerations on the impact of aviation biofuels on the materials used for sealing flange joints. The fuel type selected for the test is compatible with aviation fuels. Fuels have been enriched with a bio-additive that changes the technical and physical properties of the fuel. The tested gaskets were made of soft, aramid-elastomeric materials that were flat in shape and without reinforcement. Their commercial names are AFO and AFM. Tests were carried out with the use of a simple flange joint with a fuel reservoir at 373 K. Both fuel loss and the pressure drop on the gasket were measured during a 1000 h period of time. The experiments showed that the seals preserved the technical parameters in the presence of the tested fuels. The fuel loss did not exceed the accepted limits, which demonstrates the suitability of the tested materials for utilization with new types of fuel. However, no unequivocal conclusions can be drawn about the positive or negative impact of bio-additives on the sealing material due to the fact that both an improvement and deterioration in tightness under certain circumstances were observed. Based on the experimental data, a mathematical model was proposed that makes it possible to predict the service life of the gaskets in flange joints in contact with the investigated types of fuel. The potential application of the research results is practical information about the impact of biofuel on the gasket, and hence the information about the possibility of using traditional sealing materials in a new application-for sealing installations for the production, transmission and storage of biofuels.

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This study aims to investigate an accurate detection method to detect defects in the gasket ring groove of the blowout preventer (BOP) using the ultrasonic phased array technology. Traditionally, it is difficult to accurately determine the type and size of defects in the gasket ring groove due to the complexity of the BOP configuration and the interference between the defect echo and the structural echo when using the ultrasonic phased array detection technology. In this study, firstly, the appropriate detection process parameters are determined by using simulation software for simulating and analyzing the defects of different sizes and types in the gasket ring groove of a BOP. Thereafter, according to the detection process parameters determined by the simulation analysis, we carry out a corresponding actual detection test. Simulation analysis and detection test results show that the relative amplitude of the test results and the simulation results differ within 1 dB, and the simulation results have a guiding role for the actual detection. The defect echo and structure echo can be clearly distinguished by selecting appropriate detection process parameters, such as probe frequency 5 MHz, array elements 36, and probe aperture 16 mm. The research results can provide theoretical reference for the detection of blowout preventer.

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A gasket is an important constituent of a diamond anvil cell (DAC) assembly, responsible for the sample chamber stability at extreme conditions for X-ray diffraction studies. In this work, we studied the performance of gaskets made of metallic glass Fe0.79Si0.07B0.14 in a number of high-pressure X-ray diffraction (XRD) experiments in DACs equipped with conventional and toroidal-shape diamond anvils. The experiments were conducted in either axial or radial geometry with X-ray beams of micrometre to sub-micrometre size. We report that Fe0.79Si0.07B0.14 metallic glass gaskets offer a stable sample environment under compression exceeding 1 Mbar in all XRD experiments described here, even in those involving small-molecule gases (e.g. Ne, H2) used as pressure-transmitting media or in those with laser heating in a DAC. Our results emphasize the material's importance for a great number of delicate experiments conducted under extreme conditions. They indicate that the application of Fe0.79Si0.07B0.14 metallic glass gaskets in XRD experiments for both axial and radial geometries substantially improves various aspects of megabar experiments and, in particular, the signal-to-noise ratio in comparison to that with conventional gaskets made of Re, W, steel or other crystalline metals.

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NiTi alloy's shape memory effect provides additional restoring force under temperature loads, making it an ideal material for gaskets. However, its yield stress is too large to form the initial seal. In this paper, by combining the advantages of corrugated structure and NiTi alloy's shape memory effect, a NiTi alloy corrugated gasket is proposed. Its mechanical properties were studied using experiments and the finite element method. The influences of geometric parameters on gasket performance were discussed. The results show that the shape memory effect can greatly improve the contact stress of gaskets. The corrugation can effectively reduce the pre-tightening force. The contact stress of NiTi alloy corrugated gasket is significantly affected by plate thickness, gasket height, and corrugation pitch and shows a high nonlinear characteristic. The proposed finite element method (FEM) and the gasket contact stress prediction model are accurate and engineering available.

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Bolted flange connections are commonly used in process industries. Their sealing performance is greatly affected by the gasket. In this paper, a NiTi alloy corrugated gasket was simulated to reveal its sealing performance, considering the gasket surface roughness, shape memory effect and superelastic effect. A fluid-structure coupling analysis method that takes the real surface morphology of the gasket contact zone was proposed, and a leakage rate prediction model was established. The results showed that NiTi shape memory effect could enhance the sealing reliability in service and lower the leakage rate. The leakage rate of the NiTi alloy corrugated gasket is positively correlated with the internal pressure of the medium and the roughness of the sealing surface. The prediction model of the NiTi alloy corrugated gasket leakage rate has good reliability with an average error of about 16.81% compared with the simulation.

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The paper presents the proposal of a leakage prediction method in flange joints, after pipeline deformation, based on FEM (Finite Element Methods). The stages of developing the design are discussed, and a complex, multi-stage method of applying the loads is presented in detail. Moreover, the gasket material data obtained in experiments were used. The paper also presents the results of calculations on a non-uniform stress distribution in the radial direction of the gasket. In addition, it has been shown that the deflection of the pipeline with a minor displacement causes an increase in the diversification of the circumferential pressure of the gasket, and also has a significant influence on the determination of the actual state of stress to which the gasket is subject. Moreover, it was found that the distribution of contact pressure on the deflection of the pipeline has a significant influence on the level of leakage. The results of tests are compared to the results of the numerical calculations of the stress in bolts. By comparing the bolt tension changes obtained by numerical and experiment analyses, it has been shown that the assumptions made in developing the numerical model are correct.

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In the oil and gas industry, heat exchangers are subject to loads that cause malfunctioning. These loads are divided into thermal and mechanical stresses; however, most efforts are focused on studying thermal stresses. The present work reduces mechanical stresses by mitigating pressure events in a gasket plate heat exchanger (GPHE). GPHE requires that the hot and cold stream branches have approximately the same pressure. Thus, the work focuses on controlling the pressure difference between the branches. A test bench was used to emulate, on a small scale, the typical pressure events of an oil production plant. A control valve was used in different positions to evaluate the controller. In the experiments, it was observed that the best option to control the pressure difference is to use a hydraulic pump and control valve in the flow of the controlled thermal fluid branch. The reduction in pressure events was approximately 50%. Actuator efforts are also reduced in this configuration.

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BACKGROUND: The expanded endoscopic endonasal approach (EEA) is currently well accepted for a variety of ventral skull base tumors. Such an approach often results in a transdural defect and intraoperative cerebrospinal fluid (CSF) leak, and adequate reconstruction is necessary to prevent postoperative CSF leak and its complications. Reconstruction is usually performed using a variety of materials along with the nasoseptal flap. OBJECTIVE: This work's aim is to describe a new reconstructive technique called the "soft gasket seal" (SGS) in detail and compare it with the standard reconstructive technique at our institution for craniopharyngiomas operated via transtuberculum EEA. METHODS: A retrospective chart review was achieved to identify patients who underwent transtubercular EEA for craniopharyngioma between 2010 and 2018, by the same neurosurgical and otolaryngology team using either the SGS or standard reconstructive technique. RESULTS: Of 36 patients who met criteria and were considered for analysis, 15 of them underwent SGS reconstruction and 21 had standard reconstruction. There were 16 female (44%) and 20 male (56%) patients. The median age was 42.2 ± 20.9 years. The rate of postoperative CSF leak in the group of patients treated with the standard technique was 14.2% and 6.6% in the SGS group (odds ratio 0.43 [confidence interval 95% 0.007-6.15], P = 0.62). CONCLUSIONS: The SGS technique provides a simple reconstructive technique in conjunction with the nasoseptal flap, showing a tendency of lower complications when compared with our standard technique while avoiding donor site morbidity. Such results are encouraging, but further studies are necessary to confirm these findings.

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With the aim of enhancing both reliability and fatigue life of gasket, this study combines finite element analysis, orthogonal experimental design, dynamically-guided multi-objective optimization, and the non-dominated sorting genetic algorithm with elitist strategy to optimize the geometric parameters of the cylinder gasket. The finite element method was used to analyze the temperature field, thermal-mechanical coupling stress field, and deformation of cylinder gasket. The calculation results were experimentally validated by measured temperature data, and comparison results show that the maximum error between calculated value and experiment value is 7.1%, which is acceptable in engineering problems. Based on above results and orthogonal experiment design method, the effects of five factors, including diameter of combustion chamber circle, diameter of coolant flow hole, length of the insulation zone between third and fourth cylinders, thickness of gasket, and bolt preload, on three indexes: temperature, stress, and deformation of gasket, were examined in depth. Through the variance analysis of the results, three important factors were identified to proceed later calculation. The dynamically guided multi-objective optimization strategy and the non-dominated sorting genetic algorithm were effectively used and combined to determine the optimal geometric parameters of cylinder gasket. Furthermore, calculation results suggest that temperature, stress, and deformation of the optimized cylinder gasket have been improved by 27.88 K, 16.84 MPa, and 0.0542 mm, respectively when compared with the origin object, which shows the excellent performance of gasket optimization and effectiveness of the proposed optimization strategy.

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Recent evidence suggests that Golgi cells in the cerebellar granular layer are densely connected to each other with massive gap junctions. Here, we propose that the massive gap junctions between the Golgi cells contribute to the representational complexity of the granular layer of the cerebellum by inducing chaotic dynamics. We construct a model of cerebellar granular layer with diffusion coupling through gap junctions between the Golgi cells, and evaluate the representational capability of the network with the reservoir computing framework. First, we show that the chaotic dynamics induced by diffusion coupling results in complex output patterns containing a wide range of frequency components. Second, the long non-recursive time series of the reservoir represents the passage of time from an external input. These properties of the reservoir enable mapping different spatial inputs into different temporal patterns.

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In horizontal-axis washing machines, the front gasket as well as the damping system are crucial owing to the possible collision of the tub with the housing during the transient period. However, most dynamic models for predicting tub motion focus on the steady state and consider only the suspension system without including the gasket. We conducted an experimental study to analyze the effect of the gasket on the transient motion of the tub. The results obtained indicate the necessity of implementing the gasket in the multibody model of a washing machine to accurately predict the tub behavior during this period. The gasket model is formed by a combination of Voigt elements. Stiffness parameters are determined using a load cell, and damping factors are estimated using a process that integrates Adams/View, Matlab optimization algorithms, and displacement measurements that are taken using accelerometers. A D-optimal design used to predict the effect of the gasket parameters reveals that the tub displacement is most sensitive to the changes in linear stiffness in the transversal direction. Finally, the model of the gasket provides a better approach for predicting the tub movement during resonance that can be used in the design phase to avoid tub collision.

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In this chapter, we describe advances in endoscopic endonasal surgery that have impacted skull base meningioma surgery. After reviewing the technical innovations in endoscopy, we describe the advances as they relate to each surgical step. We discuss preoperative planning and approach and the utility of neuronavigation and neuromonitoring. We then discuss endoscopic instrumentation, technology for tumor debulking (ultrasonic aspirators, radiofrequency ablators, suction debriders), and hemostatic agents as they relate to tumor resection and hemostasis. In the end, we discuss techniques of skull base reconstruction and closure (nasoseptal flap, gasket seal and bilayer button).

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Background: Benign prostatic hyperplasia (BPH) is a common disease in elderly men. Transurethral resection of the prostate (TURP) is still the standard treatment for BPH. However, postoperative urinary incontinence (UI) is still one of the complications. Objective: This study aims to evaluate the clinical efficacy and safety of the TURP by traditional compared with preserved urethral mucosa of the prostatic apex (PUMPA). Materials and Methods: From July 2015 to June 2016, 80 patients with TURP were included and divided into the two groups: traditional nonpreserved urethral mucosa group (TURP group, n = 40) and the PUMPA group (PUMPA-TURP group, n = 40). This study identified the apex of the prostate and determined the cut position of mucosa. Then, we separated the preserved urethral mucosa, excised the hyperplastic prostate tissue, and trimmed the preserved urethral mucosa. Results: The rate of UI after PUMPA-TURP was significantly lower than that traditional TURP (0% vs 22.5%). The operative time was significantly shorter in the PUMPA-TURP group than traditional TURP group (50 ± 16.5 minutes vs 65 ± 18.5 minutes). The intraoperative bleeding loss was lower in the PUMPA-TURP group than traditional TURP group (280 ± 33 mL vs 190 ± 35 mL). International prostate symptom score, quality of life (QoL), and peak uroflowmetry data (Qmax) were similar between two groups. Conclusions: When compared with traditional TURP, PUMPA-TURP can reduce the occurrence of UI and intraoperative blood loss. Besides, PUMPA-TURP could shorten the operative time.

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