RESUMEN

BACKGROUND: The Overall Assessment of the Speaker's Experience of Stuttering for Adults (OASES-A; Yaruss & Quesal, 2016) is a widely used measurement tool designed to evaluate the adverse impact associated with stuttering. Items examine general perceptions of stuttering, personal reactions to stuttering, functional communication difficulties, and consequences for quality of life. This paper presents a shortened research version of the OASES-A response form (OASES-A-R) that can be used by researchers in scientific studies involving adults who stutter that reflect the Section and Total Scores of the original OASES-A using fewer items. METHOD: Previously collected OASES-A data (N = 315) were analyzed via graded response modeling to identify discrimination values of each OASES-A item in measuring each OASES-A Section Total Score. Items with the highest discrimination and items judged by expert clinicians to be more important in measuring adverse impact (N = 27) were used to create a shortened OASES-A-R. The shortened OASES-A-R response form was then validated and compared to the full OASES-A response form in an independent sample (N = 156). RESULTS: The shortened 25-item OASES-A-R response form demonstrated very high and positive correlations with the full OASES-A response form. Similarly, each OASES-A-R Section demonstrated high internal reliability coefficients similar to those of the OASES-A. DISCUSSION: The resulting 25-item OASES-A-R response form provides a reflection of the speaker's experience of stuttering as measured by the original 100-item OASES-A that is suitable for use in certain research studies of adults who stutter. Clinical use is not recommended, as the full OASES-A provides additional insights about a client's experience of stuttering that are necessary for effective treatment planning and intervention.

Asunto(s)

RESUMEN

BACKGROUND: Despite the risks associated with energy drinks (EDs), the consumption of EDs remains high, especially among adolescents, so the study aimed to assess the consumption pattern, awareness, perception of EDs, and their adverse impact on adolescent health. METHODS: A cross-sectional design was used. The study setting is Damanhur City, Beheira governorate, Egypt, with a sample size of 350 participants. A structured interview questionnaire was used to collect the data and consisted of five parts: socio-demographic data, pattern of use, negative adverse effects of EDs, knowledge, and perception. RESULTS: The data reveal that 38.5% of the studied sample consumed EDs, and 14.2% of them consumed more than one time per day. The main reason for consumption was feeling fatigue among 46.4%, followed by 28.7% to increase concentration. Only 36% had satisfactory awareness, and 45.7% perceived that excessive consumption has dangerous effects. Age, educational stage, gender, awareness, and perception are significant influencers on the consumption of EDs. The reported adverse impacts were polyuria among 51.4%, followed by tachycardia (40.0%) and insomnia (35%). CONCLUSION: About one-third of studied adolescents consume EDs regularly and reported several adverse health effects, such as polyuria and tachycardia. The main reason for consumption was feeling fatigued among about half of the studied adolescents. Low awareness levels and negative perceptions were significantly associated with consumption. RECOMMENDATION: Implement educational programs about EDs and their possible risks to improve the awareness level among adolescents. Further studies should be carried out across different countries.

RESUMEN

The measurement of psychological constructs is frequently based on self-report tests, which often have Likert-type items rated from "Strongly Disagree" to "Strongly Agree". Recently, a family of item response theory (IRT) models called IRTree models have emerged that can parse out content traits (e.g., personality traits) from noise traits (e.g., response styles). In this study, we compare the selection validity and adverse impact consequences of noise traits on selection when scores are estimated using a generalized partial credit model (GPCM) or an IRTree model. First, we present a simulation which demonstrates that when noise traits do exist, the selection decisions made based on the IRTree model estimated scores have higher accuracy rates and have less instances of adverse impact based on extreme response style group membership when compared to the GPCM. Both models performed similarly when there was no influence of noise traits on the responses. Second, we present an application using data collected from the Open-Source Psychometrics Project Fisher Temperament Inventory dataset. We found that the IRTree model had a better fit, but a high agreement rate between the model decisions resulted in virtually identical impact ratios between the models. We offer considerations for applications of the IRTree model and future directions for research.

RESUMEN

The predicting groundwater nitrate pollution risk, especially in terms of changes in fertilizing, has not been fully investigated so far. In particular, there is no comprehensive method to assess this risk in areas of different land use type, and not only in agricultural areas. The aim of this study was to develop a novel multicriteria methodology for groundwater nitrate pollution risk assessment, which meets these issues. A further aim was to determine how much this risk would change if the amount of organic and synthetic fertilization was reduced. An assumption was that groundwater pollution risk is a combination of the potential adverse impacts of land use, fertilization, and intrinsic groundwater vulnerability to pollution. The impact of fertilization was holistically evaluated by balancing nitrogen from spatially differentiated the size of the breeding, species of livestock, manure and synthetic fertilizers input, and spatially differentiated topsoil, with nitrogen uptake by different crops. The nitrate concentration in the leachate was used as a measure of the impact of fertilization. This concentration was compared to the natural baseline nitrate concentration in groundwater. Three fertilization scenarios for groundwater pollution risk assessment in two study areas were discussed. Under typical agricultural, climatic, soil, and geological conditions in Europe for the current total fertilization level of 95-120 kg N ha-1 groundwater nitrate pollution risk is low and moderate, but for fertilization of 150-180 kg N ha-1, a reduction in the total fertilization (synthetic and manure) by 40 to 50% may be required to achieve low risk of degradation of natural groundwater quality. Predictive simulations of groundwater nitrate pollution risk confirmed that reducing synthetic and organic fertilization has an effect, especially in areas with intensive fertilization. This method may allow for a holistic and scenario-based assessment of groundwater pollution risk and may help decision-makers introduce solutions to manage this risk under conditions of climate change, preservation of groundwater quality, and food security.

Asunto(s)

RESUMEN

La “oposición” es el método de selección de personal para los cuerpos superiores de la función pública española y cientos de miles de candidatos participan en las oposiciones cada año. A pesar de ello, permanece sin haberse estudiado su validez predictiva y sus potenciales efectos sobre la igualdad de trato para hombres y mujeres. Este artículo presenta dos estudios independientes dedicados establecer la validez predictiva y el grado de igualdad de trato de la “oposición”. En el primero se examinó con candidatos al Cuerpo de Técnicos de Hacienda. Los resultados indicaron una validez operativa ρ = .54 (N = 392) y un valor d de Cohen promedio de .14 para la igualdad de trato favorable a los hombres. El segundo estudio se realizó con candidatos al Cuerpo Superior de Inspectores de Hacienda y la validez operativa fue de ρ = .50 (N =.70) y la d de Cohen de .33 favorable a las mujeres. Los resultados indican que la “oposición” muestra una validez semejante o superior a la de los mejores instrumentos de selección de personal. Finalmente, se discuten las implicaciones para la práctica y se hacen recomendaciones para mejorar este sistema de acceso a la función pública.(AU)

The "competition” (“oposición” in Spanish) is the method of personnel selection for the higher Corps of the Spanish civil service, and hundreds of thousands of candidates participate in the competitive examinations each year. Despite this, its predictive validity and its potential effects on equal treatment for men and women remain unknown. This article presents two independent studies devoted to establishing the predictive validity and the degree of equal treatment of the "competition". In the first one, the validity was examined with candidates for the Corps of Treasury Technicians. The results indicated an operational validity ρ = .54 (N = 392) and an average Cohen's d value of .14 for equal treatment favorable to men. The second study was conducted with candidates for the Corps of Senior Treasury Inspectorate and the operational validity was ρ = .50 (N =.70) and Cohen's d of .33 favorable to women. The results indicate that the "competition" shows similar or superior validity to that of the best personnel selection instruments. Finally, implications for practice are discussed and recommendations are made to improve this system of access to the civil service.(AU)

Asunto(s)

RESUMEN

This paper explores whether a diversity and inclusion strategy focused on using modern intelligence tests can assist public safety organizations in hiring a talented diverse workforce. Doing so may offer strategies for mitigating the issues of systematic racism with which these occupations have historically struggled. Past meta-analytic research shows that traditional forms of intelligence tests, which are often used in this sector, have not consistently demonstrated predictive validity but have negatively impacted Black candidates. As an alternative, we examine a modern intelligence test that consists of novel unfamiliar cognitive problems that test takers must solve without relying on their prior experience. Across six studies of varying public safety jobs (e.g., police, firefighter) in different organizations, we found a pattern of results that supports the criterion-related validity of the modern intelligence test. In addition to consistently predicting job performance and training success, the modern intelligence test also substantially mitigated the observed Black-White group differences. The implications of these findings are discussed in terms of how to alter the legacy of I/O psychology and human resource fields when it comes to our impact on facilitating employment opportunities for Black citizens, particularly in public safety positions.

RESUMEN

Student diversity in health professions education (HPE) can be affected by selection procedures. Little is known about how different selection tools impact student diversity across programs using different combinations of traditional and broadened selection criteria. The present multi-site study examined the chances in selection of subgroups of applicants to HPE undergraduate programs with distinctive selection procedures, and their performance on corresponding selection tools. Probability of selection of subgroups (based on gender, migration background, prior education, parental education) of applicants (N = 1935) to five selection procedures of corresponding Dutch HPE undergraduate programs was estimated using multilevel logistic regression. Multilevel linear regression was used to analyze performance on four tools: prior-education grade point average (pe-GPA), biomedical knowledge test, curriculum-sampling test, and curriculum vitae (CV). First-generation Western immigrants and applicants with a foreign education background were significantly less likely to be selected than applicants without a migration background and with pre-university education. These effects did not vary across programs. More variability in effects was found between different selection tools. Compared to women, men performed significantly poorer on CVs, while they had higher scores on biomedical knowledge tests. Applicants with a non-Western migration background scored lower on curriculum-sampling tests. First-generation Western immigrants had lower CV-scores. First-generation university applicants had significantly lower pe-GPAs. There was a variety in effects for applicants with different alternative forms of prior education. For curriculum-sampling tests and CVs, effects varied across programs. Our findings highlight the need for continuous evaluation, identifying best practices within existing tools, and applying alternative tools.

Asunto(s)

RESUMEN

Objectives: Intimate partner violence (IPV) against pregnant or human immunodeficiency virus (HIV)-positive women have been previously studied. However, data on the impact of IPV on HIV-positive pregnant women have not been systematically synthesized. We performed a meta-analysis to explore this issue and provide evidence regarding IPV prevention and HIV infection control. Method: The PubMed, Web of Science, Cochrane Library, and Embase databases were systematically searched. Studies that quantitatively assessed the association between IPV and its adverse impact on HIV-positive women during pregnancy and post-partum were eligible for inclusion. Pooled odds ratios (ORs) were calculated. Findings: Eight studies were identified to meet our eligibility criteria. The adverse impacts of IPV against HIV-positive pregnant women mainly included nonadherence to maternal antiretroviral treatment during pregnancy, nondisclosure of HIV-positive status to male partners, nonadherence to infant antiretroviral prophylaxis, and antenatal depression. IPV caused a 180% and 145% increase in the odds of antenatal depression and nonadherence to infant antiretroviral prophylaxis, respectively, among HIV-positive women, compared to the odds of their IPV-free counterparts [OR = 2.80, 95% confidence interval (CI): 1.66-4.74; OR = 2.45, 95% CI: 1.40-4.27]. Conclusion: Limited evidence has suggested that IPV against HIV-positive pregnant women caused maternal depression during pregnancy and led to the possible failure of HIV prophylaxis adherence in infants. Interventions to address IPV may ultimately reduce the risk of depression-related adverse birth outcomes and vertical transmission in infants exposed to maternal HIV. Prevention and control against IPV should be developed for HIV-positive pregnant women.

Asunto(s)

RESUMEN

Tert-butyl hydroquinone (TBHQ) is a food additive commonly used as a more effective protectant in the food, cosmetic and pharmaceutical industries. However, the long-term exposure to TBHQ at higher doses (0.7 mg/kg) results in substantial danger to public health and brings a series of side effects, including cytotoxic, genotoxic, carcinogenic, and mutagenic effects. As a result, the global burden of chronic diseases has fascinated consumers and governments regarding the safety assessment of food additives. Regarding contradictory reports of various research about the application of food additives, the accurate monitoring of food additives is urgent. Notwithstanding, there are reports of the therapeutic effects of TBHQ under pathologic conditions through activation of nuclear factor erythroid 2-related factor 2. Thus, further investigations are required to investigate the impact of TBHQ on public health and evaluate its mechanism of action on various organs and cells. Therefore, this review aimed to investigate TBHQ safety through an overview of its impacts on different tissues, cells, and biological macromolecules as well as its therapeutic effects under pathologic conditions.

RESUMEN

Given that the global population of elderly individuals is expanding and the difficulty of recovery, hip fractures will be a huge challenge and a critical health issue for all of humanity. Although people have spent more time at home during the coronavirus disease 2019 (COVID-19) pandemic, hip fractures show no sign of abating. Extensive studies have shown that patients with hip fracture and COVID-19 have a multifold increase in mortality compared to those uninfected and a more complex clinical condition. At present, no detailed research has systematically analyzed the relationship between these two conditions and proposed a comprehensive solution. This article aims to systematically review the impact of COVID-19 on hip fracture and provide practical suggestions. We found that hip fracture patients with COVID-19 have higher mortality rates and more complicated clinical outcomes. Indirectly, COVID-19 prevents hip fracture patients from receiving regular medical treatment. With regard to the problems we encounter, we provide clinical recommendations based on existing research evidence and a clinical flowchart for the management of hip fracture patients who are COVID-19 positive. Our study will help clinicians adequately prepare in advance when dealing with such patients and optimize treatment decisions.

RESUMEN

Dwarfed stature is a desired trait for modern orchard production systems. One effective strategy for dwarfing cultivation is exogenously applying plant growth retardants (PGRs) to plants. However, for many economic fruit trees, the current knowledge on the regulatory mechanisms underlying the dwarfing effect of PGRs is limited, which largely restricts the agricultural application of PGRs. In this study, we exogenously applied three kinds of PGRs [paclobutrazol, daminozide (B9), and mannitol] to the seedlings of pomegranate (Punica granatum L.) and performed comparative transcriptome analysis to elucidate the molecular features of PGR-induced dwarfing in pomegranates. Our results showed that all the three PGRs could significantly suppress plant growth of pomegranate. The inhibition of auxin biosynthetic processes, as well as auxin-mediated shoot development, may be considered as the main reason for the dwarfing. Besides that, different PGRs were also found to induce dwarfing via specific mechanisms, for example, cellular response to strigolactone was particularly suppressed by the application of paclobutrazol, while the level of carbohydrate homeostasis and metabolism were downregulated in conditions of either B9 or mannitol treatments. Furthermore, exogenous PGR application was supposed to cause adverse impacts on the normal physiological process of pomegranate seedlings, which may bring extra burden to pomegranate plants. These novel findings unveiled the genetic basis underlying the dwarfing in pomegranates, which provides deeper insights into PGR-mediated dwarfing cultivation of pomegranates.

RESUMEN

Gamification and machine learning are emergent technologies in recruitment, promising to improve the user experience and fairness of assessments. We test this by validating a game based assessment of cognitive ability with a machine learning based scoring algorithm optimised for validity and fairness. We use applied data from 11,574 assessment completions. The assessment has convergent validity (r = 0.5) and test-retest reliability (r = 0.68). It maintains fairness in a separate sample of 3,107 job applicants, showing that fairness-optimised machine learning can improve outcome parity issues with cognitive ability tests in recruitment settings. We show that there are no significant gender differences in test taking anxiety resulting from the games, and that anxiety does not directly predict game performance, supporting the notion that game based assessments help with test taking anxiety. Interactions between anxiety, gender and performance are explored. Feedback from 4,778 job applicants reveals a Net Promoter score of 58, indicating more applicants support than dislike the assessment, and that games deliver a positive applicant experience in practise. Satisfaction with the format is high, but applicants raise face validity concerns over the abstract games. We encourage the use of gamification and machine learning to improve the fairness and user experience of psychometric tests.

RESUMEN

Lichen sclerosus of the vulva (LSV) is seen frequently enough to warrant knowing how to diagnose it and institute appropriate treatment strategies. LSV is a chronic skin disorder, very likely of autoimmune origin, which may affect various areas of the perineum, although some women may be affected in extragenital areas. The disease has significant adverse impact on quality of life and sexual activity and may undergo malignant transformation. History of symptomatology and clinical examination is sufficient to make the diagnosis. Skin biopsy is only necessary in specific scenarios. Topical corticosteroids are still the mainstay of therapy, initially to institute remission and then for maintenance. Long-term therapy and surveillance are invariably necessary. Surgery does have a role, but only in specific associated conditions. A number of alternative treatment options have been mooted, especially if the disease is resistant to topical corticosteroids, but these options are still being assessed and studied.

Asunto(s)

RESUMEN

Pesticides are among the top-priority contaminants, which significantly contribute to environmental deterioration. Conventional techniques are not efficient enough to remove pollutants from environmental matrices. The development of functional materials has emerged as promising candidates to remove and degrade pesticides and related hazardous compounds. Furthermore, the nanohybrid materials with unique structural and functional characteristics, such as better material anchorage, mass transfer, electron-hole separation, and charged interaction make them a versatile option to treat and reduce pollutants from aqueous matrices. Herein, we present the current progress in the development of functional materials for the abatement of toxic pesticides. The physicochemical characteristics and pesticide-removal functionalities of various metallic functional materials (e.g., zirconium, zinc, titanium, tungsten, and iron), polymer, and carbon-based materials are critically discussed with suitable examples. Finally, the industrial-scale applications of the functional materials, concluding remarks, and future directions in this important arena are given.

Asunto(s)

RESUMEN

Immense epidemiological studies have been indicated about adverse effects of the welding fumes on the health of the welders, especially respiratory problems and other physiological disorders. The different types of welding mechanisms produce aerosols/fumes that contain different metals including chromium (Cr) and manganese (Mn). In the present study, the welders of two age groups (adolescents and adults) were selected; simultaneously the age-matched adolescents and adults belong to nonindustrial area as referents/control subjects. Biological samples (scalp hair) were collected from welders and referents, along with analyzed for Cr and Mn by electrothermal atomic absorption spectrometer, prior to acid digestion. To evaluate the occupational exposure on the health of the workers, the clinical features and biochemical parameters of selected population (exposed and non-exposed age-matched groups) were also carried out. The resulted data indicated that the concentrations of Mn and Cr were significantly higher in scalp hair samples of welders as compared to referent subjects (p < 0.01), verifying the absorption/exposure of both metals produced in welding fumes. The high prevalence of anemia and stomach disorder was observed in adolescent than adult welding workers. The incidence of asthma and related symptoms was elevated in adult welders than in younger boys. The neurological problems were particularly observed in aged welders > 50 years, might be due to long time exposure of welding fumes contains different toxicant especially Mn in ill ventilation system of workshops.

Asunto(s)

RESUMEN

Objective: Adult-onset Still's disease (AOSD) is an autoinflammatory disease with a higher prevalence rate in young females. The purpose of this study is to investigate whether AOSD has an adverse impact on pregnancy outcomes, or conversely exacerbated by pregnancy. Methods: The outcomes of 191 pregnancies were evaluated in 86 female patients with AOSD. The generalized linear mixed model and propensity score matching method were conducted to evaluate the influence of AOSD on pregnancy outcomes. A dependent sample sign test was applied to assess the impact of pregnancy on the relapse of AOSD. Results: The results showed that the post-AOSD group had a lower proportion of normal delivery (25.0 vs. 52.4%, p = 0.036) and a higher proportion of spontaneous abortion (STA) (18.8 vs. 0.6%, p = 0.002) compared with the pre-AOSD group. Moreover, pregnancy after being diagnosed with AOSD was a significant high risk factor of STA (adjusted OR = 4.577, 95% CI: 4.166-845.119; p = 0.003). Disease flare upon conception was observed in one of 16 post-AOSD pregnancies (p = 1.000). There were 11 patients with new-onset AOSD during gestation or postpartum, among which five (45.4%) evolved into the polycyclic course. Conclusions: AOSD patients might suffer from a higher risk of STA, however, pregnancy might not be related with the exacerbation of diagnosed AOSD. New-onset AOSD during gestation or postpartum tend to evolve into the polycyclic course.

RESUMEN

BACKGROUND: There are limited data on multiple sclerosis (MS) patients in underserved groups, including Puerto Rico. In this study, we analyzed the characteristic of MS symptoms and number of relapses in Puerto Rican patients. We then compare these characteristics with MS patients from the US. The number of MS relapses is highly correlated with the treatment onset and adherence. Patients in Puerto Rico have been experiencing lengthy treatment delay. We will discuss the possible causes of such delay and its impact on MS prognosis. METHODS: This retrospective cohort study consisted of the evaluation of 325 medical records from MS patients attending the Caribbean Neurological Center from 2014 to 2019. We gathered symptoms and comorbidities data as binary objects. The treatment delay was calculated based on the mean value of days between diagnosis and treatment onset for these groups of patients. RESULTS: We found that on average, the treatment delay for MS patients in Puerto Rico (PR) to receive their medication was 120 days. The most common MS subtype was relapsing-remitting 72.8%, with a mean of 1.684 relapses per year. Initial symptoms were sensory 54%, visual 33.1%, motor 28.8%, coordination 23.2%, fatigue 9.7%, memory 7.3%, depression 6.5%, urinary 4.9%, gastrointestinal 2.4%, and sexual dysfunction 1.6%. The most common comorbidities were hypertension 18.4%, asthma 13.6%, and thyroid disease 12.8%. When we compared the comorbidities between the two populations, immune thrombocytopenia had the highest percent change with the value of almost 200% (0.001% of US patient vs. 0.8% of Puerto Rican MS patients). CONCLUSION: Patients from Puerto Rico had a 33% higher relapse rate compared to the one reported for MS patients in the US. This higher rate may be related to the long delay in receiving their medications. They also had a higher rate of complex comorbidities such as immune thrombocytopenia or thyroid disease. Our findings provide a proof of concept that delay in receiving medications can increase the number of relapses and complex comorbidities among MS patients.

RESUMEN

To assess the impact of repeat performances (familiarisation) plus exercise training on completion time for the Ontario Wildland Firefighter (WFF) Fitness Test circuit (WFX-FIT), normally active general population participants (n = 145) were familiarised to the protocol then randomised into (i) exercise training, (ii) circuit only weekly performances or (iii) controls. At Baseline, the WFX-FIT pass rate for all groups combined was 11% for females and 73% for males, indicating that the Ontario WFX-FIT standard had a possible adverse impact on females. Following test familiarisation, mean circuit completion times improved by 11.9% and 10.2% for females and males, respectively. There were significant improvements in completion time for females (19.8%) and males (16.9%) who trained, plus females (12.2%) and males (9.8%) who performed the circuit only, while control participants were unchanged. Post training, the pass rate of the training group was 80% for females and 100% for males. Practitioner Summary: This paper details the impact of familiarisation plus exercise training as accommodation to mitigate potential adverse impact on initial attack wildland firefighter test performance. The results underscore the importance of test familiarisation opportunities and physical fitness training programmes that are specific to the demands of the job.

Asunto(s)

RESUMEN

Situational Judgment Tests (SJTs) are increasingly used for medical school selection. Scoring an SJT is more complicated than scoring a knowledge test, because there are no objectively correct answers. The scoring method of an SJT may influence the construct and concurrent validity and the adverse impact with respect to non-traditional students. Previous research has compared only a small number of scoring methods and has not studied the effect of scoring method on internal consistency reliability. This study compared 28 different scoring methods for a rating SJT on internal consistency reliability, adverse impact and correlation with personality. The scoring methods varied on four aspects: the way of controlling for systematic error, and the type of reference group, distance and central tendency statistic. All scoring methods were applied to a previously validated integrity-based SJT, administered to 931 medical school applicants. Internal consistency reliability varied between .33 and .73, which is likely explained by the dependence of coefficient alpha on the total score variance. All scoring methods led to significantly higher scores for the ethnic majority than for the non-Western minorities, with effect sizes ranging from 0.48 to 0.66. Eighteen scoring methods showed a significant small positive correlation with agreeableness. Four scoring methods showed a significant small positive correlation with conscientiousness. The way of controlling for systematic error was the most influential scoring method aspect. These results suggest that the increased use of SJTs for selection into medical school must be accompanied by a thorough examination of the scoring method to be used.

Asunto(s)

RESUMEN

This study investigated the effects of the alginate and polyvinyl alcohol (PVA) entrapment on the viability of Escherichia coli cells exposed to single wall carbon nanotubes (SWCNTs) with a diameter of 1-2nm. Viability was examined using a galactosidase enzyme assay, LIVE/DEAD BacLight assay, and total ribonucleic acid quantity. Variables studied included SWCNT concentration (5, 10, 20, 50, 100, 200, 500, and 1000µg/ml), SWCNT length (0.5-2µm for short SWCNTs and 5-30µm for long SWCNTs), and initial bacterial concentration (6.5 log10 CFU and 9 log10 CFU per test). Results showed that both alginate and PVA entrapments mitigate the bactericidal effect of SWCNTs. At the highest SWCNT concentration tested (1000µg/ml), the viability of the cells relative to controls (systems with only E. coli, no SWCNTs), was 0-60% for free cells and 60-90% for alginate and PVA entrapped cells. The bactericidal effect depended on SWCNT type and concentration, and bacterial concentration. In general, long SWCNTs (5-30µm) caused significantly greater reductions in the viability of entrapped cells than the short SWCNTs except for the two highest SWCNT concentrations studied, 500 and 1000µg/ml. Microscopy showed that the entrapment matrices prevented SWCNTs from entering the beads. This study shows that bacterial entrapment is effective at limiting the bactericidal effect of SWCNTs.

Asunto(s)