RESUMEN
OBJECTIVE: Little national data exist regarding service use patterns for children with autism spectrum disorder (ASD) of varying severity. This study aimed to assess the relationship between parent-reported severity and use of educational and health care services. METHODS: Data from the 2011 Survey of Pathways to Diagnosis and Services were used to examine a nationally representative sample of 1420 US children aged 6 to 17 years with ASD, with or without developmental delay and intellectual disability. Weighted multivariable logistic regression assessed associations of parent-reported ASD severity and child sociodemographic characteristics with school-based therapy, non-school-based therapy, behavioral interventions, and specialty provider visits. RESULTS: Higher parent-reported ASD severity was associated with increased likelihood of current use of school-based therapy (adjusted odds ratio [AOR] = 4.08, 95% confidence interval =1.85-8.98), non-school-based therapy (AOR = 3.60 [1.95-6.66]), and behavioral interventions (AOR = 2.30 [1.22-4.34]), as well as regular specialty provider visits (AOR = 2.99 [1.38-6.46]). Although rates of service use were generally highest among children with severe ASD, non-school-based therapy and behavioral interventions were only used by about half of children with severe ASD, and about 1 in 4 children with mild ASD were using none of the therapies asked about. CONCLUSION: Parent-reported severity is associated with increased therapy and specialty provider service use among children with ASD. However, substantial variability exists in service use across levels of severity.
Asunto(s)
Trastorno del Espectro Autista/epidemiología , Atención a la Salud/estadística & datos numéricos , Educación Especial/estadística & datos numéricos , Padres , Adolescente , Trastorno del Espectro Autista/psicología , Trastorno del Espectro Autista/terapia , Trastorno Autístico/epidemiología , Trastorno Autístico/psicología , Trastorno Autístico/terapia , Niño , Femenino , Humanos , Masculino , Padres/psicología , Índice de Severidad de la Enfermedad , Encuestas y Cuestionarios , Estados UnidosRESUMEN
BACKGROUND: Although most individuals with intellectual disability (ID) currently reside in the community and receive their health care in general medical settings, there is no specific literature on psychiatric consultation to those requiring inpatient medical or surgical care. OBJECTIVE: The authors discuss the specialized features of the consultation-liaison (C-L) evaluation and common requests for psychiatric consultation in the hospitalized ID population. METHOD: This article reviews the literature on general psychiatric care in this population and presents the experience of practitioners in the ID-Psychiatry field who have followed their patients through episodes of inpatient non-psychiatric care. RESULTS: The C-L clinician must adapt the interview to accommodate a patient's cognitive, sensory, and language capacities; integrate information from collateral sources; and serve as a liaison between multiple parties. DISCUSSION: ID should not be a barrier to the delivery of appropriate health care. This article provides evidence and recommendations on C-L assessment, management, and liaison for hospitalized individuals with ID.
Asunto(s)
Discapacidad Intelectual/psicología , Psiquiatría , Derivación y Consulta , Agresión/psicología , Evaluación de la Discapacidad , Quimioterapia/psicología , Humanos , Discapacidad Intelectual/terapia , Entrevista Psicológica , Alta del Paciente , Conducta Autodestructiva/psicología , Ideación SuicidaRESUMEN
The long-term effects of low-level lead intoxication are not known. The sympathetic skin response (SSR) was evaluated in a group of 60 former workers of a primary lead smelter, located in Santo Amaro, BA, Brazil. The individuals participating in the study were submitted to a clinical-epidemiological evaluation including questions related to potential risk factors for intoxication, complaints related to peripheral nervous system (PNS) involvement, neurological clinical examination, and also to electromyography and nerve conduction studies and SSR evaluation. The sample consisted of 57 men and 3 women aged 34 to 69 years (mean +/- SD: 46.8 +/- 6.9). The neurophysiologic evaluation showed the presence of lumbosacral radiculopathy in one of the individuals (1.7%), axonal sensorimotor polyneuropathy in 2 (3.3%), and carpal tunnel syndrome in 6 (10%). SSR was abnormal or absent in 12 cases, representing 20% of the sample. More than half of the subjects (53.3%) reported a history of acute abdominal pain requiring hospitalization during the period of work at the plant. A history of acute palsy of radial and peroneal nerves was reported by about 16.7 and 8.3% of the individuals, respectively. Mean SSR amplitude did not differ significantly between patients presenting or not the various characteristics in the current neurological situation, except for diaphoresis. The results suggest that chronic lead intoxication induces PNS damage, particularly affecting unmyelinated small fibers. Further systematic study is needed to more precisely define the role of lead in inducing PNS injury.
Asunto(s)
Respuesta Galvánica de la Piel/efectos de los fármacos , Intoxicación por Plomo/fisiopatología , Conducción Nerviosa/efectos de los fármacos , Exposición Profesional/efectos adversos , Enfermedades del Sistema Nervioso Periférico/inducido químicamente , Sistema Nervioso Simpático/efectos de los fármacos , Adulto , Anciano , Electromiografía , Femenino , Humanos , Masculino , Persona de Mediana Edad , Enfermedades del Sistema Nervioso Periférico/diagnóstico , Tiempo de Reacción , Factores de Riesgo , Factores de TiempoRESUMEN
The long-term effects of low-level lead intoxication are not known. The sympathetic skin response (SSR) was evaluated in a group of 60 former workers of a primary lead smelter, located in Santo Amaro, BA, Brazil. The individuals participating in the study were submitted to a clinical-epidemiological evaluation including questions related to potential risk factors for intoxication, complaints related to peripheral nervous system (PNS) involvement, neurological clinical examination, and also to electromyography and nerve conduction studies and SSR evaluation. The sample consisted of 57 men and 3 women aged 34 to 69 years (mean ± SD: 46.8 ± 6.9). The neurophysiologic evaluation showed the presence of lumbosacral radiculopathy in one of the individuals (1.7 percent), axonal sensorimotor polyneuropathy in 2 (3.3 percent), and carpal tunnel syndrome in 6 (10 percent). SSR was abnormal or absent in 12 cases, representing 20 percent of the sample. More than half of the subjects (53.3 percent) reported a history of acute abdominal pain requiring hospitalization during the period of work at the plant. A history of acute palsy of radial and peroneal nerves was reported by about 16.7 and 8.3 percent of the individuals, respectively. Mean SSR amplitude did not differ significantly between patients presenting or not the various characteristics in the current neurological situation, except for diaphoresis. The results suggest that chronic lead intoxication induces PNS damage, particularly affecting unmyelinated small fibers. Further systematic study is needed to more precisely define the role of lead in inducing PNS injury.
Asunto(s)
Humanos , Masculino , Femenino , Adulto , Persona de Mediana Edad , Respuesta Galvánica de la Piel/efectos de los fármacos , Plomo/toxicidad , Conducción Nerviosa/efectos de los fármacos , Exposición Profesional/efectos adversos , Enfermedades del Sistema Nervioso Periférico/inducido químicamente , Sistema Nervioso Simpático/efectos de los fármacos , Electromiografía , Enfermedades del Sistema Nervioso Periférico/diagnóstico , Tiempo de Reacción , Factores de Riesgo , Factores de TiempoRESUMEN
AIM: To report the effect of enzyme replacement therapy (ERT) in sympathetic skin responses (SSR) of patients with Fabry disease. PATIENTS AND METHODS: Seven male patients were included in an open-label protocol using agalsidase-alfa, continued at regular intervals. Five patients completed 24 months of ERT and two of them completed 18 months. Two main measurements were performed at baseline, as well as 1 and 2 years after ERT: (1) a standard neurological examination (NE), with a detailed evaluation of the sensory perception of light touch, pinprick, cold, hot, and vibratory stimuli; (2) the SSR amplitudes. RESULTS: Although there were no significant differences between NE in this time period, all patients reported general improvement in their subjective reports of acroparaesthesia and sweating. Before starting ERT, the SSR amplitudes were either too small (3/7 patients) or absent (4/7 patients): the average (range) amplitude of 122 microV (0 through 492) was statistically smaller than that found in a control group, i.e. 1453.6 microV (619.7-2754) (p<0.0001, t-test). Mean +/- SD SSR amplitude increased to 1088+/- 690 microV in the second year of ERT, reaching the range found in a normal control group (p=0.004). CONCLUSION: ERT improved SSR continuously in Fabry patients in 2 years of observation. Although the mechanism of the SSR improvement is unknown, this response to ERT can be clinically significant if it reflects a normalization in sweating.
Asunto(s)
Terapia Enzimática , Enfermedad de Fabry/tratamiento farmacológico , Piel/patología , alfa-Galactosidasa/farmacología , Factores de Edad , Estudios de Casos y Controles , Preescolar , Análisis Mutacional de ADN , Humanos , Isoenzimas/farmacología , Masculino , Datos de Secuencia Molecular , Mutación , Examen Neurológico , Proteínas Recombinantes , Factores de TiempoRESUMEN
BACKGROUND: Visual evoked potentials (VEPs) and brain stem auditory evoked potentials (BAEPs) have been proposed as tools in the diagnosis of subclinical hepatic encephalopathy (HE). However, little information exists to determine their usefulness in pediatric patients. This study was undertaken to evaluate both methods in the detection of subclinical HE in pediatric liver transplant candidates. METHODS: VEPs and BAEPs were recorded in 15 pediatric liver transplant candidates with no clinical signs of HE. The wave latencies found in these examinations were then compared with those in 16 healthy controls of similar age. Laboratory data on liver function and electroencephalographic data from the patients were also recorded to examine their correlation with the evoked potentials results. RESULTS: No differences were found in the BAEP results between patients and controls. However, in the VEPs, the liver transplant candidates had significantly prolonged N1 (N75) latencies when compared with controls; no significant delay was found in the other waves. In contrast, among the children with liver disease, higher BAEP peak latencies correlated positively with electroencephalographic abnormalities, but this correlation was not observed in VEPs. CONCLUSIONS: Evoked potentials might be of use in detecting alterations related to HE in children. However, further studies are necessary to determine their sensitivity and specificity in this situation.
Asunto(s)
Potenciales Evocados Auditivos del Tronco Encefálico , Potenciales Evocados Visuales , Encefalopatía Hepática/diagnóstico , Trasplante de Hígado , Adolescente , Niño , Preescolar , Electroencefalografía/métodos , Potenciales Evocados Auditivos del Tronco Encefálico/fisiología , Potenciales Evocados Visuales/fisiología , Femenino , Encefalopatía Hepática/fisiopatología , Humanos , Pruebas de Función Hepática , MasculinoRESUMEN
PURPOSE: To assess the effects of retrobulbar and peribulbar anesthesia on nerve function as detected by visual-evoked potentials (VEPs). SETTING: University hospital in southern Brazil. METHODS: In a prospective study, 7 patients had peribulbar anesthesia and 9 had retrobulbar anesthesia for extracapsular cataract extraction. Visual-evoked potentials with pattern reversal and flash stimulation were performed at least 1 month before and 1 month after surgery. Study participants did not have ocular pathology other than cataract. The Lens Classification System III was used to grade the opacities before surgery. RESULTS: No significant difference was found between preoperative and postoperative evaluations in VEP flash and pattern-reversal amplitude and latency in either group (P >.05). Postoperative amplitude and latency was not significantly different between the peribulbar and retrobulbar groups. Two cases in the peribulbar group had altered wave morphology without clinical manifestation postoperatively. All patients had a final best spectacle-corrected visual acuity of 20/20. CONCLUSION: Block anesthetic procedures were safely used in cataract surgery, with no clinical sequelae to the optic nerve.