RESUMEN

Marine algae are valuable sources of bioactive compounds that have the potential to be used in the management of various pathologies. Despite the increasing prevalence of NAFLD, the absence of an approved effective pharmacological treatment with demonstrable effectiveness persists. In this context, the aim of the present study is to assess the effect of Gracilaria vermiculophylla red seaweed dietary supplementation on hepatic lipid accumulation, as well as on oxidative stress, inflammation and fibrosis- related markers on obese fa/fa Zucker rats fed with a standard diet, supplemented or not with 2.5% or 5% dehydrated Gracilaria vermiculophylla. After a six-week supplementation with the macroalga, no significant reduction in hepatic total lipid content or hepatic triglyceride content was observed. However, both doses were able to diminish hepatic NEFA concentration by reducing de novo lipogenesis and increasing mitochondrial biogenesis. Moreover, supplementation with the dose of 2.5% improved some oxidative stress and inflammation-related markers. Supplementation with the dose of 5% did not exert these clear beneficial effects. Thus, this study demonstrates that while Gracilaria vermiculophylla may not mitigate hepatic steatosis, it could exert protective effects on the liver by reducing NEFA content and enhancing oxidative stress and inflammation parameters.

RESUMEN

The Mediterranean diet is a dietary pattern typical of the populations living in the Mediterranean basin during the 50s-60s of the last century. This diet has demonstrated beneficial effects in the prevention of several pathologies such as cardiovascular diseases, metabolic syndrome, or several cancer types, at least in part, due to its antioxidant compounds. Since the COVID-19 pandemic started, different authors have been studying the effects of certain dietary habits on the presence of COVID-19 and its severity, and the Mediterranean diet is one of them. This review gathers data from studies supporting the potential usefulness of the main phenolic compounds present in the Mediterranean diet, based on their antioxidant and anti-inflammatory effects, as preventive/therapeutic agents against COVID-19. The current evidence supports the potential benefits that hydroxytyrosol, resveratrol, flavonols such as quercetin, flavanols like catechins, and flavanones on the order of naringenin could have on COVID-19. This is due to the increase in the synthesis and translocations of Nrf-2, which increases the activity of antioxidant enzymes and thus reduces ROS production, the scavenging of free radicals, and the suppression of the activity of MMP-9, which is involved in the cytokine storm, and the inhibition of NF-κB. (AU)

Asunto(s)

Humanos , Infecciones por Coronavirus/epidemiología , Infecciones por Coronavirus/prevención & control , Dieta Mediterránea , Pandemias , Antioxidantes/farmacología , Antioxidantes/uso terapéutico , Inflamación/tratamiento farmacológico , Inflamación/prevención & control , Polifenoles/farmacología , Polifenoles/uso terapéutico

RESUMEN

The Mediterranean diet is a dietary pattern typical of the populations living in the Mediterranean basin during the 50s-60s of the last century. This diet has demonstrated beneficial effects in the prevention of several pathologies such as cardiovascular diseases, metabolic syndrome, or several cancer types, at least in part, due to its antioxidant compounds. Since the COVID-19 pandemic started, different authors have been studying the effects of certain dietary habits on the presence of COVID-19 and its severity, and the Mediterranean diet is one of them. This review gathers data from studies supporting the potential usefulness of the main phenolic compounds present in the Mediterranean diet, based on their antioxidant and anti-inflammatory effects, as preventive/therapeutic agents against COVID-19. The current evidence supports the potential benefits that hydroxytyrosol, resveratrol, flavonols such as quercetin, flavanols like catechins, and flavanones on the order of naringenin could have on COVID-19. This is due to the increase in the synthesis and translocations of Nrf-2, which increases the activity of antioxidant enzymes and thus reduces ROS production, the scavenging of free radicals, and the suppression of the activity of MMP-9, which is involved in the cytokine storm, and the inhibition of NF-κB.

Asunto(s)

COVID-19 , Dieta Mediterránea , Humanos , Polifenoles/farmacología , Polifenoles/uso terapéutico , Antioxidantes/farmacología , Antioxidantes/uso terapéutico , Pandemias , COVID-19/prevención & control , Inflamación/tratamiento farmacológico , Inflamación/prevención & control

RESUMEN

Although a general healthy gut microbiota cannot be defined due to numerous internal and external individual factors, such as sex, age, ethnicity, genetics, environment, diet and drugs affect its composition, certain microbial species and gut microbiota compositions seem to be related to the progression of insulin resistance to type 2 diabetes, as well as the development of microvascular and macrovascular complications of diabetes. The present review aimed at gathering the reported information describing how resveratrol induced changes in microbiota composition can mediate the positive effects of this polyphenol on glucose homeostasis under type 2 diabetic conditions, both in animals and humans. Based on the fact that some changes observed in the gut microbiota of type 2 diabetic animals and patients are reversed by resveratrol treatment, and taking into account that some resveratrol mediated changes in gut microbiota composition are similar to those induced by anti-diabetic drugs such as metformin, it can be proposed that four genera, Alistipes, Allobaculum, Desulfovibrio and Blautia could be involved in the benefits of resveratrol on glycameic control. Nevertheless some limitations are observed in this research field: (a) the number of studies analyzing both the effects of resveratrol on glucose homeostasis and microbiota composition in the same cohort of animals, in order to know the potential involvement of microbiota in the anti-diabetic effects of this phenolic compound, are very scarce and practically inexistent in the case of humans., (b) the studies present inconsistencies concerning the effects of resveratrol on gut microbiota changes, (c) the experimental design used do not allow the researchers to establish a causal relationship between the changes in microbiota and the anti-diabetic effect, in the vast majority of the studies, (d) the knowledge about the role of each type of bacteria on glycaemic control is not sufficient so far.

RESUMEN

Numerous studies have revealed the beneficial effects of moderate beer consumption on cardiovascular diseases. However, the presence of alcohol in beer can represent a matter of concern, since alcohol intake poses a risk to some individuals. Additionally, adults who are life-long abstainers should not be encouraged to consume alcohol for health purposes. Consequently, the benefits of beer consumption remain a controversial issue. In this scenario, the present review gathers the reported information concerning the cardiovascular effects of non-alcoholic beer, and makes a comparison between these effects and those of conventional beer. Despite the scarcity of published results to date describing the effects of non-alcoholic beer consumption, the available literature indicates that it is more effective than conventional beer in preventing oxidative stress (lower lipid and protein oxidation), preserving the endothelial function (lower endothelial dysfunction) and inhibiting thrombogenic activity (lowered oxidized LDL). By contrast, conventional beer has shown to induce greater increases in HDL-cholesterol levels (known as a cardiovascular protective factor) compared to non-alcoholic beer. This effect cannot be solely attributed to alcohol content, since the polyphenol content in conventional beer tends to be higher than that found in non-alcoholic beer.

Asunto(s)

Enfermedades Cardiovasculares , Sistema Cardiovascular , Adulto , Humanos , Cerveza/análisis , Consumo de Bebidas Alcohólicas/efectos adversos , Enfermedades Cardiovasculares/prevención & control , Etanol/farmacología , Biomarcadores

RESUMEN

Metabolic syndrome (MetS) greatly increases the risk of cardiovascular diseases and type 2 diabetes mellitus. The aim of this study was to evaluate the efficacy of functional snacks containing a combination of wakame (W) and carob pod (CP) flours in reducing markers associated with MetS. The mechanisms of action underlying these effects were also evaluated. In vitro approaches were carried out in mature 3T3-L1 adipocytes and RAW 264.7 macrophages treated with different doses of extracts from W, CP, or a combination of both. Furthermore, an in vivo experiment was conducted in rats with MetS treated with normal-caloric diets containing different snack formulations with combinations of 1/50 (snack A) or 1/5 of wakame/carob (snack B). In vitro experiments results indicated that both W and CP had delipidating effects, but only the latter induced anti-inflammatory and anti-hypertensive effects. As far as the in vivo study is concerned, snack B was ineffective and snack A showed an anti-hypertensive effect in rats with MetS. The present study shows for the first time the in vitro efficacy of a W and CP combination as an anti-inflammatory, delipidating, and anti-hypertensive tool, and its potential usefulness in treating MetS.

Asunto(s)

Alimentos Funcionales , Galactanos/farmacología , Mananos/farmacología , Síndrome Metabólico/dietoterapia , Extractos Vegetales/farmacología , Gomas de Plantas/farmacología , Undaria/química , Animales , Antiinflamatorios/farmacología , Antiinflamatorios/uso terapéutico , Antihipertensivos/farmacología , Antihipertensivos/uso terapéutico , Presión Sanguínea/efectos de los fármacos , Dieta Alta en Grasa/efectos adversos , Modelos Animales de Enfermedad , Fabaceae/química , Galactanos/uso terapéutico , Humanos , Masculino , Mananos/uso terapéutico , Síndrome Metabólico/etiología , Ratones , Extractos Vegetales/uso terapéutico , Gomas de Plantas/uso terapéutico , Células RAW 264.7 , Ratas , Ratas Wistar , Bocadillos , Resultado del Tratamiento

RESUMEN

No disponible

---

Scientific research is constantly looking for new molecules to be used as functional ingredients to combat obesity. The aim of the present study was to analyse whether resveratrol and conjugated linoleic acid (CLA) together could reduce body fat more efficiently than their separate administration. Thirty-six male Wistar rats were randomly divided into four groups: controls rats (C), rats treated with resveratrol (RSV), rats treated with CLA (CLA) and rats treated with a combination of resveratrol and CLA (RSV+CLA). All rats were fed on an obesogenic diet. In RSV and RSV+CLA groups, the rats received 30 mg resveratrol/kg body weight/day. In CLA and RSV+CLA groups, an equimolecular mixture of trans-10,cis-12 and cis-9,trans-11 was added to the diet to reach 0.5% of the active isomer trans-10,cis-12. After 6 weeks of treatment, white adipose tissue from different anatomical locations was dissected and weighed. Serum triacylglycerols, total and HDL cholesterols, glucose, insulin, fructosamine and TNF-á were measured. A glucose tolerance test was also performed. Separately, resveratrol and CLA significantly reduced body fat but did not do so when combined: 20% in the RSV group and 18% in CLA group but 7% in the RSV+CLA group. Resveratrol reduced serum triacylglycerols. No differences were found among groups in serum cholesterol. Resveratrol, as well as the combination RSV+CLA, improved glycaemic control. These results demonstrate that the combination RSV+CLA reduces the effectiveness of each compound on body fat-lowering action, but it maintains the positive effect of resveratrol on glycaemic control. Consequently, this combination has no usefulness in obesity prevention (AU)

Asunto(s)

Animales , Ratas , Ácidos Linoleicos Conjugados/farmacocinética , Obesidad/prevención & control , Antioxidantes/farmacocinética , Medicamento Fitoterápico , Modelos Animales de Enfermedad , Sustancias Protectoras/farmacocinética , Índice Glucémico , Quimioterapia Combinada

RESUMEN

Scientific research is constantly looking for new molecules to be used as functional ingredients to combat obesity. The aim of the present study was to analyse whether resveratrol and conjugated linoleic acid (CLA) together could reduce body fat more efficiently than their separate administration. Thirty-six male Wistar rats were randomly divided into four groups: controls rats (C), rats treated with resveratrol (RSV), rats treated with CLA (CLA) and rats treated with a combination of resveratrol and CLA (RSV+CLA). All rats were fed on an obesogenic diet. In RSV and RSV+CLA groups, the rats received 30 mg resveratrol/kg body weight/day. In CLA and RSV+CLA groups, an equimolecular mixture of trans-10,cis-12 and cis-9,trans-11 was added to the diet to reach 0.5% of the active isomer trans-10,cis-12. After 6 weeks of treatment, white adipose tissue from different anatomical locations was dissected and weighed. Serum triacylglycerols, total and HDL cholesterols, glucose, insulin, fructosamine and TNF-α were measured. A glucose tolerance test was also performed. Separately, resveratrol and CLA significantly reduced body fat but did not do so when combined: 20% in the RSV group and 18% in CLA group but 7% in the RSV+CLA group. Resveratrol reduced serum triacylglycerols. No differences were found among groups in serum cholesterol. Resveratrol, as well as the combination RSV+CLA, improved glycaemic control. These results demonstrate that the combination RSV+CLA reduces the effectiveness of each compound on body fat-lowering action, but it maintains the positive effect of resveratrol on glycaemic control. Consequently, this combination has no usefulness in obesity prevention.

Asunto(s)

Ácidos Linoleicos Conjugados/farmacología , Obesidad/prevención & control , Estilbenos/farmacología , Tejido Adiposo Blanco/metabolismo , Tejido Adiposo Blanco/patología , Animales , Área Bajo la Curva , Glucemia , Peso Corporal/efectos de los fármacos , Evaluación Preclínica de Medicamentos , Quimioterapia Combinada , Ingestión de Energía/efectos de los fármacos , Prueba de Tolerancia a la Glucosa , Lípidos/sangre , Masculino , Tamaño de los Órganos/efectos de los fármacos , Ratas , Ratas Wistar , Resveratrol , Insuficiencia del Tratamiento

RESUMEN

OBJECTIVE: Little evidence exists concerning the effects of trans-10,cis-12 conjugated linoleic acid (CLA) under energy restriction. Thus, the effects of this CLA isomer on adipose tissue size, liver composition, as well as on expression and activity of carnitine-palmitoyl transferase I (CPT-I) and acyl CoA oxidase (ACO), in hamsters fed an energy-restricted diet were analyzed. METHODS: Hamsters were fed a high-fat diet for 7 wk and then subjected to 25% energy-restricted diets supplemented with 0.5% linoleic acid or 0.5% trans-10,cis-12 CLA for 3 wk. Serum insulin, free-triiodothyronine and non-esterified fatty acid levels, liver triacylglycerol, protein and water contents, and CPT-I, ACO, and Peroxisome proliferator-activated receptor alpha (PPARα) expressions and enzyme activities were assessed. RESULTS: Energy restriction reduced liver size, serum levels of insulin, free-triiodothyronine, and non-esterified fatty acid and increased CPT-I activity. Liver composition was not modified. No differences were found between both restricted groups, with the exception of CPT-I and ACO oxidative enzyme activities, which were greater in hamsters fed the CLA diet. CONCLUSIONS: Energy restriction does not cause trans-10,cis-12 CLA to induce liver hyperplasia. Although this CLA isomer increases liver CPT-I and ACO activities, this effect does not result in reduced hepatic triacylglyerol content or decreased adipose tissue size. Consequently, this CLA isomer seems not to be a useful tool for inclusion in body weight loss strategies followed during obesity treatment.

Asunto(s)

Acil-CoA Oxidasa/metabolismo , Restricción Calórica , Carnitina O-Palmitoiltransferasa/metabolismo , Ácidos Linoleicos Conjugados/farmacología , Peroxidación de Lípido/efectos de los fármacos , Hígado/efectos de los fármacos , Obesidad/tratamiento farmacológico , Animales , Cricetinae , Grasas de la Dieta/efectos adversos , Suplementos Dietéticos , Ácidos Grasos no Esterificados/sangre , Hiperplasia , Insulina/sangre , Isomerismo , Ácido Linoleico/farmacología , Hígado/metabolismo , Hígado/patología , Masculino , Mesocricetus , Obesidad/metabolismo , Obesidad/patología , Triyodotironina/sangre

RESUMEN

It has been proposed that young animals and subjects are more responsive to conjugated linoleic acid (CLA) than the adults. Nevertheless, there is very little information concerning the effectiveness of CLA in adult animals. In the present study we aimed to explore the effects of trans-10, cis-12-CLA on body fat accumulation in adult hamsters, as well as on some of the molecular mechanisms described in young animals as responsible for the CLA body fat-lowering effect, such as lipogenesis, lipoprotein lipase (LPL)-mediated fat uptake and thermogenesis. The experiment was conducted with sixteen adult male Syrian Golden hamsters (aged 8 months) fed a high-fat diet supplemented or not with 0.5 % trans-10, cis-12-CLA for 6 weeks. Acetyl-CoA carboxylase (ACX), fatty acid synthase (FAS), LPL, PPARgamma, sterol regulatory element-binding protein (SREBP)-1a and SREBP-1c expressions were assessed in subcutaneous and perirenal adipose tissues by real-time RT-PCR. Total and heparin-releasable LPL activities were determined in subcutaneous adipose tissue by fluorimetry and FAS activity by spectrophotometry. Uncoupling protein-1 (UCP1) expression in interscapular brown adipose tissue was assessed by Western blot. Hamsters fed the trans-10, cis-12-CLA diet showed a significant reduction in subcutaneous adipose tissue. No changes were observed in the expression of ACX, FAS, LPL, SREBP-1a, SREBP-1c and PPARgamma, nor in total and heparin-releasable LPL and FAS activities. Trans-10, cis-12-CLA induced a significant increase in the amount of UCP1. These results suggest a low responsiveness to trans-10, cis-12-CLA in adults, lower than that in young hamsters. One of the reasons explaining this difference is the lack of effect on LPL.

Asunto(s)

Tejido Adiposo/efectos de los fármacos , Ácidos Linoleicos Conjugados/farmacología , Tejido Adiposo/enzimología , Tejido Adiposo Pardo/efectos de los fármacos , Tejido Adiposo Pardo/metabolismo , Tejido Adiposo Blanco/efectos de los fármacos , Tejido Adiposo Blanco/enzimología , Animales , Peso Corporal/efectos de los fármacos , Peso Corporal/fisiología , Cricetinae , Ingestión de Alimentos/efectos de los fármacos , Ingestión de Alimentos/fisiología , Regulación Enzimológica de la Expresión Génica , Canales Iónicos/metabolismo , Lipogénesis/efectos de los fármacos , Masculino , Mesocricetus , Proteínas Mitocondriales/metabolismo , Reacción en Cadena de la Polimerasa de Transcriptasa Inversa/métodos , Grasa Subcutánea/enzimología , Factores de Transcripción/metabolismo , Proteína Desacopladora 1

RESUMEN

OBJECTIVE: To analyze the effects of high-fat high-sucrose (HFHS) feeding, energy restriction, and trans-10,cis-12 conjugated linoleic acid (CLA) on visfatin and apelin. DESIGN: A randomized dietary intervention study. SETTING: Free-living individuals studied in metabolic cages. SUBJECTS: Thirty-two male Syrian Golden hamsters (82.6 +/- 1.4 g). INTERVENTIONS: Standard and HFHS feeding for 7 weeks. After that, some hamsters fed the HFHS diet were submitted for 3 weeks to a 25% energy restriction with or without trans-10,cis-12 CLA supplementation (0.5%). RESULTS: Feeding animals an HFHS diet resulted in increased body fat and reduced insulin sensitivity. No changes were observed in the expression and serum levels of visfatin and apelin, or in peroxisome proliferator-activated receptor (PPAR)gamma and Sirt1 expression. Energy restriction reduced body fat and normalized insulin sensitivity. Visfatin showed increased serum levels without changes in expression. No modifications were found as far as apelin was concerned. Sirt1 expression was increased, and PPARgamma remained unchanged. With regard to trans-10,cis-12 CLA, no changes were induced by its addition to the restricted diet. CONCLUSIONS: Insulin function impairment induced by HFHS feeding is not mediated by visfatin and apelin. However, visfatin can play a role in improving insulin sensitivity associated with energy restriction. These results suggest that visfatin may not have evolved as a molecule that reserves the action of insulin when food is widely available, but rather that its function seems to be associated with energy restriction adaptation. In general terms, trans-10,cis-12 CLA did not modify changes induced by energy restriction.

Asunto(s)

Tejido Adiposo/metabolismo , Proteínas Portadoras/metabolismo , Grasas de la Dieta/administración & dosificación , Sacarosa en la Dieta/administración & dosificación , Ácido Linoleico/administración & dosificación , Nicotinamida Fosforribosiltransferasa/metabolismo , Tejido Adiposo/efectos de los fármacos , Análisis de Varianza , Animales , Peso Corporal/efectos de los fármacos , Proteínas Portadoras/genética , Cricetinae , Ensayo de Inmunoadsorción Enzimática , Insulina/sangre , Resistencia a la Insulina/fisiología , Leptina/sangre , Masculino , Mesocricetus , Nicotinamida Fosforribosiltransferasa/genética , PPAR gamma/genética , PPAR gamma/metabolismo , Distribución Aleatoria , Reacción en Cadena de la Polimerasa de Transcriptasa Inversa

RESUMEN

The aim of the present work was to study the potential involvement of hypothalamic galanin system in the anorectic mechanism of fluoxetine in obese Zucker rats. Male obese Zucker (fa/fa) rats were administered fluoxetine (10 mg/kg; i.p.) daily for two weeks. The control group was given 0.9% NaCl solution. Significant decreases in food intake, final body weight and total body fat were observed after fluoxetine treatment. Although fluoxetine-treated rats showed a decrease in urine elimination, this effect was not enough to compensate decreased water intake, leading to dehydration, as showed by decreased body water content. Chronic fluoxetine administration increased the numbers of galanin positively immunostained neural cells in medial and lateral preoptic areas, lateral hypothalamic area and paraventricular nucleus (rostral and magnocellular regions), without changes in dorsomedial, ventromedial, supraoptic, suprachiasmatic and arcuate nuclei. Taken into account that galanin stimulates appetite, these results could represent rather a compensatory response against reduced food intake than a direct anorectic mechanism. Changes in the magnocellular region of the hypothalamic paraventricular nucleus suggest a role for galanin neural circuits at this level in fluoxetine-induced hydro-osmotic impairment.

Asunto(s)

Fluoxetina/administración & dosificación , Galanina/análisis , Hipotálamo/química , Hipotálamo/efectos de los fármacos , Obesidad/metabolismo , Inhibidores Selectivos de la Recaptación de Serotonina/administración & dosificación , Tejido Adiposo , Animales , Composición Corporal , Peso Corporal/efectos de los fármacos , Ingestión de Alimentos/efectos de los fármacos , Masculino , Núcleo Hipotalámico Paraventricular/química , Núcleo Hipotalámico Paraventricular/efectos de los fármacos , Área Preóptica/química , Área Preóptica/efectos de los fármacos , Ratas , Ratas Zucker

RESUMEN

OBJECTIVE: The aim of this work was to study the potential involvement of neuropeptide Y (NPY) and orexins in the anorexigenic mechanism of fluoxetine in obese Zucker rats, assessing the effects of chronic fluoxetine treatment on NPY and orexin immunostaining in several hypothalamic regions. RESEARCH METHODS AND PROCEDURES: Male obese Zucker (fa/fa) rats were administered fluoxetine (10 mg/kg intraperitoneally) daily for 2 weeks. The control group was administered 0.9% NaCl solution. Carcass composition was assessed using the official methods of the Association of Official Analytical Chemists. To test the potential thermogenic effect of fluoxetine administration, total body oxygen consumption was measured daily for 60 minutes before fluoxetine or saline injection and for 30 minutes after drug or saline injection. Hypothalamic arcuate and paraventricular nuclei, and the lateral hypothalamic area were immunostained for NPY, orexin A, and orexin B. Commercial kits were used for serum determinations. RESULTS: Chronic fluoxetine administration in obese Zucker rats generated a reduction in body weight gain, food intake, adipocyte size, fat mass, and body protein. A decrease in NPY immunostaining in the paraventricular nucleus, without changes in the arcuate, was observed. However, no changes were observed in the number of neural cells immunostained for orexin A or orexin B in the lateral hypothalamic area. DISCUSSION: Due to the hyperphagic effect of NPY in the paraventricular nucleus, these results suggest that NPY, but not orexins, could be involved in the anorexigenic effect of fluoxetine in obese Zucker rats.

Asunto(s)

Proteínas Portadoras/metabolismo , Fluoxetina/farmacología , Hipotálamo/efectos de los fármacos , Péptidos y Proteínas de Señalización Intracelular , Neuropéptido Y/metabolismo , Neuropéptidos/metabolismo , Obesidad/metabolismo , Inhibidores Selectivos de la Recaptación de Serotonina/farmacología , Adipocitos , Tejido Adiposo/patología , Animales , Glucemia/análisis , Composición Corporal , Peso Corporal , Proteínas Portadoras/análisis , Tamaño de la Célula , Ingestión de Líquidos , Ingestión de Alimentos , Fluoxetina/administración & dosificación , Hipotálamo/química , Hipotálamo/metabolismo , Técnicas para Inmunoenzimas , Leptina/sangre , Masculino , Neuropéptido Y/análisis , Neuropéptidos/análisis , Orexinas , Tamaño de los Órganos , Consumo de Oxígeno , Ratas , Ratas Zucker , Hormonas Tiroideas/sangre , Triglicéridos/sangre

RESUMEN

En este trabajo se han caracterizado nutritivamente las semillas de tres especies de leguminosas: guisante (Pisum sativum), haba (Vicia faba) y soja (Glycine max). A partir de las mismas se han elaborado por vía húmeda dos tipos de concentrados de proteína que difieren en el método de secado (liofilizados y lavados con alcohol). En ellos se ha determinado la composición nutritiva proximal y el contenido en diversos factores antinutritivos (filatos, taninos, inhibidores de tripsina y lestinas). También se han estudiado en estos concentrados tres de las propiedades funcionales más importantes para su aplicación en tecnología de alimentos (solubilidad de la proteína a diferente pH, capacidad de absorción de agua y capacidad de absorción de aceite). Los resultados han puesto de manifiesto el elevado contenido proteíco de los concentrados, con rendimientos de extracción de la proteíca menores,para los concentrados lavados con alcohol que para los liofilizados, e inferiores en los obtenidos a partir de la soja que en los correspondientes al guisante y el haba. También se han encontrado en todos los concentrados niveles más bajos de factores antinutritivos con respaecto a sus semillas. Así mismo, se ha comparado que las propiedades funcionales que poseen los concentrados proteicos de guisante y de haba son tan aceptables para su utilización en tecnología de alimentos como las de los concentrados de soja

Asunto(s)

Fabaceae , Valor Nutritivo , Tabla de Composición de los Alimentos