Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 2 de 2
Filtrar
Más filtros











Intervalo de año de publicación
1.
Braz Oral Res ; 30(1): e129, 2016 Dec 22.
Artículo en Inglés | MEDLINE | ID: mdl-28001239

RESUMEN

Fetuin-A is a potent inhibitor of calcium-phosphate precipitation and of the calcification process, therefore it can also be related with dental calculus. Thus, we aimed to investigate a possible relationship between fetuin-A gene polymorphism and the presence of dental calculus. A possible relationship between serum, saliva and gingival crevicular fluid (GCF) levels of fetuin-A was also investigated. Fetuin-A c.742C > T and c.766C > G polymorphisms were investigated in 103 patients with or without dental calculus. Additionally, serum, saliva and GCF fetuin-A levels of patients were compared according to dental calculus presence. A significant difference was not observed in the distribution of the fetuin-A c.742C > T and c.766C > G polymorphisms between patients with or without dental calculus. Saliva and GCF fetuin-A concentrations of patients with dental calculus were statistically higher than those without dental calculus (P=0.001, P=0.036 respectively). According to our results, fetuin-A c.742C > T and c.766C > G polymorphisms were not associated with presence of dental calculus. However, higher GCF and saliva fetuin-A levels were detected in patients with dental calculus than in patients without dental calculus, which may result from an adaptive mechanism to inhibit mineral precipitation and eventually calculus formation.


Asunto(s)
Cálculos Dentales/química , Líquido del Surco Gingival/química , Polimorfismo Genético , Saliva/química , alfa-2-Glicoproteína-HS/análisis , alfa-2-Glicoproteína-HS/genética , Adulto , Análisis de Varianza , Estudios de Casos y Controles , Cálculos Dentales/genética , Cálculos Dentales/fisiopatología , Placa Dental/química , Ensayo de Inmunoadsorción Enzimática , Femenino , Estudios de Asociación Genética , Genotipo , Líquido del Surco Gingival/fisiología , Humanos , Masculino , Persona de Mediana Edad , Valores de Referencia , Saliva/fisiología , Estadísticas no Paramétricas , Adulto Joven
2.
Braz. oral res. (Online) ; 30(1): e129, 2016. tab
Artículo en Inglés | LILACS | ID: biblio-952043

RESUMEN

ABSTRACT: Fetuin-A is a potent inhibitor of calcium-phosphate precipitation and of the calcification process, therefore it can also be related with dental calculus. Thus, we aimed to investigate a possible relationship between fetuin-A gene polymorphism and the presence of dental calculus. A possible relationship between serum, saliva and gingival crevicular fluid (GCF) levels of fetuin-A was also investigated. Fetuin-A c.742C > T and c.766C > G polymorphisms were investigated in 103 patients with or without dental calculus. Additionally, serum, saliva and GCF fetuin-A levels of patients were compared according to dental calculus presence. A significant difference was not observed in the distribution of the fetuin-A c.742C > T and c.766C > G polymorphisms between patients with or without dental calculus. Saliva and GCF fetuin-A concentrations of patients with dental calculus were statistically higher than those without dental calculus (P=0.001, P=0.036 respectively). According to our results, fetuin-A c.742C > T and c.766C > G polymorphisms were not associated with presence of dental calculus. However, higher GCF and saliva fetuin-A levels were detected in patients with dental calculus than in patients without dental calculus, which may result from an adaptive mechanism to inhibit mineral precipitation and eventually calculus formation.


Asunto(s)
Humanos , Masculino , Femenino , Adulto , Adulto Joven , Polimorfismo Genético , Saliva/química , Cálculos Dentales/química , Líquido del Surco Gingival/química , alfa-2-Glicoproteína-HS/análisis , alfa-2-Glicoproteína-HS/genética , Valores de Referencia , Saliva/fisiología , Ensayo de Inmunoadsorción Enzimática , Cálculos Dentales/fisiopatología , Cálculos Dentales/genética , Estudios de Casos y Controles , Análisis de Varianza , Líquido del Surco Gingival/fisiología , Estadísticas no Paramétricas , Placa Dental/química , Estudios de Asociación Genética , Genotipo , Persona de Mediana Edad
SELECCIÓN DE REFERENCIAS
DETALLE DE LA BÚSQUEDA