RESUMEN
Purpose. To describe the frequency of head and/or pancreas uncinate process uptake of 99mTc-HYNIC-TOC, to study its nature, and analyze its diagnostic value. Materials and methods. Retrospective evaluation of 47 consecutive 99mTc-HYNIC-TOC examinations was conducted. Head and/or pancreas uncinate process uptake was considered to be physiological in patients with normal CT at the same episode and in follow-up. It was analyzed if age or diabetes mellitus was justifying the existence or not of uptake. Results. 32.5% patients showed uptake; 73% of them were mild. 84.6% patients with uptake have no pathology and 4% had neuroendocrine pancreatic disease at CT. Neither the age nor the diabetes mellitus established differences in patients without lesion. Conclusions. Near one-third of patients show physiological uptake by head and/or pancreas uncinate process at 99mTc-HYNIC-TOC scintigraphy. It seems that neither the diabetes nor the ages are factors that determine this physiological uptake (AU)
No disponible
Asunto(s)
Humanos , Receptores de Somatostatina/análisis , Tecnecio/administración & dosificación , Receptores de Somatostatina/efectos de la radiación , Tumores Neuroendocrinos , Polipéptido Pancreático/efectos de la radiación , Estudios Retrospectivos , Tomografía Computarizada de Emisión de Fotón Único/métodosRESUMEN
PURPOSE: To describe the frequency of head and/or pancreas uncinate process uptake of 99mTc-HYNIC-TOC, to study its nature, and analyze its diagnostic value. MATERIALS AND METHODS: Retrospective evaluation of 47 consecutive 99mTc-HYNIC-TOC examinations was conducted. Head and/or pancreas uncinate process uptake was considered to be physiological in patients with normal CT at the same episode and in follow-up. It was analyzed if age or diabetes mellitus was justifying the existence or not of uptake. RESULTS: 32.5% patients showed uptake; 73% of them were mild. 84.6% patients with uptake have no pathology and 4% had neuroendocrine pancreatic disease at CT. Neither the age nor the diabetes mellitus established differences in patients without lesion. CONCLUSIONS: Near one-third of patients show physiological uptake by head and/or pancreas uncinate process at 99mTc-HYNIC-TOC scintigraphy. It seems that neither the diabetes nor the ages are factors that determine this physiological uptake.
Asunto(s)
Tumores Neuroendocrinos/diagnóstico por imagen , Tumores Neuroendocrinos/metabolismo , Octreótido/análogos & derivados , Compuestos de Organotecnecio/metabolismo , Páncreas/diagnóstico por imagen , Páncreas/metabolismo , Cintigrafía/métodos , Receptores de Somatostatina/metabolismo , Adulto , Anciano , Anciano de 80 o más Años , Femenino , Estudios de Seguimiento , Humanos , Masculino , Persona de Mediana Edad , Tumores Neuroendocrinos/patología , Octreótido/metabolismo , Páncreas/patología , Pronóstico , Estudios Retrospectivos , Tomografía Computarizada por Rayos XRESUMEN
Presentamos el caso de una paciente de 35 años, nuligesta, con antecedentes de quistectomía ovárica bilateral hace 3 años por un teratoma monodérmico tipo struma ovarii en ovario derecho y quiste hemorrágico en ovario izquierdo. En revisiones periódicas se observa crecimiento progresivo de la tumoración anexial izquierda por lo que se le realiza una nueva laparoscopia y ante los hallazgos se le practica una quistectomía de ovario izquierdo, salpinguectomía derecha y exéresis de múltiples implantes peritoneales. El diagnóstico anatomopatológico fue de struma ovarii izquierdo y strumosis peritoneal. Posteriormente se le realiza rastreo corporal total con 99mTc-pertecnetato para detectar otros implantes peritoneales y SPECT-TAC para localizarlos anatómicamente. Esta exploración ayudó a tomar una decisión terapéutica(AU)
We report the case of a 35-year-old nulliparous woman, with a previous history of ovarian cystectomy diagnosed 3 years earlier due a struma ovarii type of monodermal teratoma in the right ovary and a hemorrhagic cyst in the left ovary. Progressive growth of the left adnexal mass was observed in the periodic medical check-ups. Due to this, a second laparoscopy was performed and, based on the findings, a left ovarian cystectomy, right salpingectomy and resection of multiple peritoneal implants were carried out. The pathology diagnosis was left struma ovarii and peritoneal strumosis. A whole body and SPECT/CT scan with 99mTc-pertechnetate was performed to detect possible peritoneal implants. This study helped to make the therapeutic decision(AU)
Asunto(s)
Humanos , Femenino , Adulto , Estruma Ovárico/diagnóstico , Pentetato de Tecnecio Tc 99m , Tomografía Computarizada de Emisión de Fotón Único , Yodo/uso terapéutico , Estruma Ovárico , Cavidad Peritoneal/patología , Cavidad Peritoneal , Enfermedades Peritoneales , Estomas Peritoneales , Medicina NuclearRESUMEN
We report the case of a 35-year-old nulliparous woman, with a previous history of ovarian cystectomy diagnosed 3 years earlier due a struma ovarii type of monodermal teratoma in the right ovary and a hemorrhagic cyst in the left ovary. Progressive growth of the left adnexal mass was observed in the periodic medical check-ups. Due to this, a second laparoscopy was performed and, based on the findings, a left ovarian cystectomy, right salpingectomy and resection of multiple peritoneal implants were carried out. The pathology diagnosis was left struma ovarii and peritoneal strumosis. A whole body and SPECT/CT scan with (99m)Tc-pertechnetate was performed to detect possible peritoneal implants. This study helped to make the therapeutic decision.
Asunto(s)
Imagen Multimodal , Neoplasias Ováricas/patología , Neoplasias Peritoneales/secundario , Tomografía de Emisión de Positrones , Radiofármacos , Pertecnetato de Sodio Tc 99m , Estruma Ovárico/secundario , Tomografía Computarizada por Rayos X , Imagen de Cuerpo Entero , Adulto , Femenino , Bocio/complicaciones , Bocio/diagnóstico por imagen , Bocio/radioterapia , Hemorragia/etiología , Hemorragia/cirugía , Humanos , Hallazgos Incidentales , Radioisótopos de Yodo/uso terapéutico , Quistes Ováricos/complicaciones , Quistes Ováricos/cirugía , Neoplasias Ováricas/complicaciones , Neoplasias Ováricas/diagnóstico por imagen , Neoplasias Ováricas/cirugía , Ovariectomía , Neoplasias Peritoneales/diagnóstico por imagen , Neoplasias Peritoneales/cirugía , Radiofármacos/uso terapéutico , Salpingectomía , Estruma Ovárico/complicaciones , Estruma Ovárico/diagnóstico por imagen , Estruma Ovárico/cirugíaAsunto(s)
Neoplasias Óseas/secundario , Neoplasias de la Mama/patología , Carcinoma/secundario , Costillas/lesiones , Tomografía Computarizada de Emisión de Fotón Único , Tomografía Computarizada por Rayos X , Heridas no Penetrantes/diagnóstico por imagen , Adulto , Diagnóstico Diferencial , Femenino , Humanos , Osteoblastos/patologíaAsunto(s)
Neoplasias de la Mama/diagnóstico por imagen , Radioisótopos de Galio , Linfoma no Hodgkin/diagnóstico por imagen , Recurrencia Local de Neoplasia/diagnóstico por imagen , Tomografía de Emisión de Positrones , Radiofármacos , Anciano de 80 o más Años , Protocolos de Quimioterapia Combinada Antineoplásica/uso terapéutico , Neoplasias de la Mama/tratamiento farmacológico , Femenino , Humanos , Linfoma no Hodgkin/tratamiento farmacológico , Recurrencia Local de Neoplasia/tratamiento farmacológico , Inducción de Remisión , Tomografía Computarizada por Rayos XAsunto(s)
Humanos , Femenino , Anciano de 80 o más Años , Linfoma , Espectrometría gamma , Neoplasias de la Mama , Radioisótopos de GalioRESUMEN
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Asunto(s)
Humanos , Masculino , Anciano , Embolia Pulmonar/diagnóstico , Hipertiroidismo/diagnóstico , Hallazgos Incidentales , Espectrometría gamma/métodosRESUMEN
No disponible
Asunto(s)
Femenino , Anciano , Humanos , Tomografía Computarizada de Emisión/métodos , Hernia Diafragmática/etiología , Cardiomiopatías , Cuerpos Extraños , Diafragma/lesionesRESUMEN
PURPOSE: The purpose of this study was to retrospectively evaluate the hypothyroidism rate, persistence of hyperthyroidism and the complications after the administration of 131I in 3 cohorts defined according to the activity of 131I administered. METHODS: We consecutively treated 659 patients diagnosed with Graves-Basedow disease (GBD) with 131I. The activity was determined on the basis of a protocol that we called "modulated fixed activity". A total of 45 patients (Group 1) who had previously undergone surgery were given small 131I activities of between 111-185 MBq (3-5 mCi), 247 patients (Group 2) with normal or almost normal-sized thyroids were given activities of between 222-333 MBq (6-9 mCi) and the 367 patients with diffuse goiters (Group 3) activities of between 370-555 MBq (10-15 mCi). RESULTS: A total of 69.2 % of the patients presented hypothyroidism at the end of the follow-up period. By groups, the percentages of hypothyroidism at the end of the follow-up period were 69 %, 68.8 % and 69.6 % respectively. The average time for the patients to present hypothyroidism was 2.7 years with a maximum de 12.3 years and a minimum of 2 months. No severe precocious complications after the administration of 131I were noted. CONCLUSION: The choice of the modulated fixed doses of 131I for treatment of the GBD is a simple method and permit treatment in only one day.
Asunto(s)
Enfermedad de Graves/radioterapia , Radioisótopos de Yodo/uso terapéutico , Adolescente , Adulto , Anciano , Anciano de 80 o más Años , Protocolos Clínicos , Femenino , Humanos , Hipotiroidismo/epidemiología , Hipotiroidismo/etiología , Radioisótopos de Yodo/efectos adversos , Masculino , Persona de Mediana EdadRESUMEN
Objetivo. Evaluar la tasa de hipotiroidismo, la persistencia de hipertiroidismo y las complicaciones después de la administración de 131I en tres cohortes definidas según la actividad de 131I administrada. Métodos. Se han tratado consecutivamente con 131I 659 pacientes diagnosticados de enfermedad de Graves-Basedow (EGB). La actividad a administrar se determinó sobre la base de un protocolo que denominamos "actividad fija modulada". Cuarenta y cinco pacientes (grupo 1) a los que previamente se les había realizado cirugía recibieron actividades de 131I comprendidas entre 111-185 MBq (3-5 mCi), 247 pacientes (grupo 2) con glándulas tiroideas de tamaño normal o casi normal actividades de 222-333 MBq (6-9 mCi) y 367 pacientes con bocio difuso (grupo 3) actividades de 370-555 MBq (10-15 mCi). Resultados. El 69,2 % de los pacientes presentaron hipotiroidismo al final del período de seguimiento. Por grupos los porcentajes fueron de 69, 68,8 y 69,6 % respectivamente. El tiempo medio en el que los pacientes presentaron hipotiroidismo fue de 2,7 años, con un máximo de 12,3 años y un mínimo de dos meses. No observamos complicaciones precoces graves tras la administración de 131I. Conclusión. La elección de una actividad fija modulada de 131I para el tratamiento de la EGB es un método simple y permite su realización en un solo día
Purpose. The purpose of this study was to retrospectively evaluate the hypothyroidism rate, persistence of hyperthyroidism and the complications after the administration of 131I in 3 cohorts defined according to the activity of 131I administered. Methods. We consecutively treated 659 patients diagnosed with Graves-Basedow disease (GBD) with 131I. The activity was determined on the basis of a protocol that we called "modulated fixed activity". A total of 45 patients (Group 1) who had previously undergone surgery were given small 131I activities of between 111-185 MBq (3-5 mCi), 247 patients (Group 2) with normal or almost normal-sized thyroids were given activities of between 222-333 MBq (6-9 mCi) and the 367 patients with diffuse goiters (Group 3) activities of between 370-555 MBq (10-15 mCi). Results. A total of 69.2 % of the patients presented hypothyroidism at the end of the follow-up period. By groups, the percentages of hypothyroidism at the end of the follow-up period were 69 %, 68.8 % and 69.6 % respectively. The average time for the patients to present hypothyroidism was 2.7 years with a maximum de 12.3 years and a minimum of 2 months. No severe precocious complications after the administration of 131I were noted. Conclusion. The choice of the modulated fixed doses of 131I for treatment of the GBD is a simple method and permit treatment in only one day
Asunto(s)
Masculino , Femenino , Niño , Adolescente , Adulto , Persona de Mediana Edad , Anciano , Humanos , 3-Yodobencilguanidina/farmacología , Enfermedad de Graves/tratamiento farmacológico , Hipotiroidismo/tratamiento farmacológico , Hipertiroidismo/tratamiento farmacológico , Enfermedad de Graves/epidemiología , 3-Yodobencilguanidina/administración & dosificación , Protocolos Clínicos , Hipotiroidismo/diagnóstico , Hipotiroidismo/fisiopatología , Hipertiroidismo/diagnóstico , Hipertiroidismo/fisiopatología , Electrocardiografía/métodos , Estudios de CohortesAsunto(s)
Infecciones Urinarias/diagnóstico por imagen , Niño , Preescolar , Pruebas Diagnósticas de Rutina , Humanos , Lactante , Pielonefritis/diagnóstico por imagen , Cintigrafía , Radiofármacos/uso terapéutico , Ácido Dimercaptosuccínico de Tecnecio Tc 99m , Reflujo Vesicoureteral/diagnóstico por imagenRESUMEN
No disponible
Asunto(s)
Preescolar , Niño , Lactante , Humanos , Infecciones Urinarias , Reflujo Vesicoureteral , Radiofármacos , Pielonefritis , Ácido Dimercaptosuccínico de Tecnecio Tc 99m , Pruebas Diagnósticas de RutinaAsunto(s)
Muerte Encefálica/diagnóstico por imagen , Cintigrafía/métodos , Accidentes de Tránsito , Adulto , Lesiones Encefálicas/diagnóstico por imagen , Circulación Cerebrovascular , Hematoma Subdural/diagnóstico por imagen , Hematoma Subdural/etiología , Humanos , Masculino , Radiofármacos/uso terapéutico , Exametazima de Tecnecio Tc 99m , Tomografía Computarizada por Rayos XRESUMEN
No disponible
Asunto(s)
Adulto , Masculino , Humanos , Tomografía Computarizada por Rayos X , Radiofármacos , Exametazima de Tecnecio Tc 99m , Cintigrafía , Circulación Cerebrovascular , Accidentes de Tránsito , Hematoma Subdural , Muerte Encefálica , Lesiones Traumáticas del EncéfaloRESUMEN
BACKGROUND: Until now, preoperative parathyroid imaging has been considered unnecessary because currently available techniques do not provide any better results than an expert surgeon. We conducted a multicenter prospective study evaluating the capability of technetium 99m sestamibi scintigraphy in the preoperative identification of pathologic glands. METHODS: Ninety-three patients with hyperparathyroidism, seven of them reoperative cases, were studied. In addition, 20 age-matched normocalcemic control subjects were also studied. RESULTS: Surgical confirmation of scintigraphic images was obtained in 91 of 93 cases (sensitivity, 97.8%). In all reoperative cases (n = 7), in all cases of ectopic glands (whether operated or not; n = 6), and in all patients with a single-gland disease (n = 70), topographic identification of the pathologic gland was correct in 100%. In multiple-gland disease (n = 23), involvement of more than one gland was visualized in only 61% of the patients; however, in 91% of patients, at least one gland was localized. Surgical success-defined as postoperative normocalcemia-with this approach was 100%. All scans of normocalcemic control subjects were negative. Of 31 patients in whom a multinodular goiter coexisted, seven presented a significant radionuclide background at 120 minutes' scan. False-positive images were found together with those corresponding to the pathologic glands in only three cases. CONCLUSIONS: 99mTc-sestamibi is a highly reliable, sensitive, and specific technique for imaging of pathologic glands in hyperparathyroidism, especially in single-gland disease. It may be considered as a first line single-procedure when a preoperative topographic diagnosis is required.
Asunto(s)
Hiperparatiroidismo/diagnóstico por imagen , Radiofármacos , Tecnecio Tc 99m Sestamibi , Adulto , Anciano , Femenino , Humanos , Hiperparatiroidismo/cirugía , Masculino , Persona de Mediana Edad , Cuidados Preoperatorios , Estudios Prospectivos , Cintigrafía , Reproducibilidad de los Resultados , Sensibilidad y EspecificidadRESUMEN
The aim of this study was to establish the usefulness of Tc-99m human polyclonal immunoglobulin (HIG) imaging in a group of patients who were suspected of having inflammatory bowel disease (IBD). The authors performed 30 scans (15 with Tc-99m HMPAO leukocytes and 15 with Tc-99m HIG) on 15 patients with IBD. Ten patients had Crohn's disease and five had ulcerative colitis. The sensitivity of Tc-99m HIG scintigraphy for detecting IBD was 33%, while the sensitivity of Tc-99m HMPAO leukocyte imaging was 100%. The Tc-99m HMPAO leukocyte imaging also detected a larger number of affected segments and provided better image quality of the extent of disease than Tc-99m HIG. On the basis of these results, the authors believe that Tc-99m HIG imaging is not a useful technique in the evaluation of patients with IBD, in the identification of location, or the extension or degree of disease activity.