Calcinosis cutis with large extension and uncommon location in a dog
Acta sci. vet. (Impr.)
; 49(suppl.1): Pub.595-Jan 4, 2021. ilus
Article
em En
| VETINDEX
| ID: biblio-1458458
Biblioteca responsável:
BR68.1
Localização: BR68.1
ABSTRACT
Background:
Calcinosis cutis is an uncommon dermatopathy characterized by the deposition of minerals in the skin,usually involving collagen and elastic fibers in the dermis. Usually, it results from dystrophic calcification and can begeneralized or focal. The dermatopathy may be primary or secondary to certain disorders, especially chronic proliferativeotitis, foreign body reactions, hyperadrenocorticism (HAC) and less frequently percutaneous penetration of calcium-richproducts. The aim of this report is to describe a presentation of calcinosis cutis affecting the skin of the back, internal faceof hind limbs and anal region of a 9-years-old bitch.Case A 9-year-old, non-defined breed, bitch, ovariohysterectomized, weighing 9.45 kg, was attended at the DermatologicalService of companion animals at the Veterinary Hospital of the Federal University of Jataí (UFJ). The animal came in withthe complaint of extensive dorsal alopecia, covered by firm lesions, with a 3-month evolution, additionally to polyuria andpolydipsia. After physical examination, alopecic areas of great extension were confirmed on the dorsum, on the internalsurface of the hind limbs and in the anal region. Also, an exudative and painful lesion located on the back was detected,plus loss of elasticity of the ventral abdomen skin and visible abdominal vessels. The screening tests showed a markedincrease in the alanine aminotransferase enzyme (ALT), alkaline phosphatase (ALP) and total cholesterol. The specificurinary density was decreased. On the ultrasound examination, hepatomegaly and an increase in the caudal pole of the leftadrenal were detected. Based on these findings, calcinosis cutis secondary to spontaneous hyperadrenocorticism (HAC)was suspected. For confirmation, skin biopsy and low dose dexamethasone suppression test (LDDS) were performed.LDDS test showed no reduction of serum cortisol after 8 h of dexamethasone dose administration and histopathological...Palavras-chave
Texto completo:
1
Base de dados:
VETINDEX
Assunto principal:
Dermatopatias
/
Calcinose
/
Hiperfunção Adrenocortical
Limite:
Animals
Idioma:
En
Revista:
Acta sci. vet. (Impr.)
/
Acta sci. vet. (Online)
Ano de publicação:
2021
Tipo de documento:
Article