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Increase resistant rates and ESBL production between E. coli isolates causing urinary tract infection in young patients from Iran
Pourakbari, Babak; Ferdosian, Farzad; Mahmoudi, Shima; Teymuri, Mostafa; Sabouni, Farah; Heydari, Hossein; Taghi Haghi Ashtiani, Mohammad; Mamishi, Setareh.
Afiliação
  • Pourakbari, Babak; Tehran University of Medical Sciences Pediatrics Infectious Diseases Research Center.
  • Ferdosian, Farzad; Yazd University of Medical Sciences Departament Pediatrics Infectious Disease.
  • Mahmoudi, Shima; Tehran University of Medical Sciences Pediatrics Infectious Diseases Research Center.
  • Teymuri, Mostafa; Tehran University of Medical Sciences Pediatrics Infectious Diseases Research Center.
  • Sabouni, Farah; Tehran University of Medical Sciences School of Medicine Department of Infectious Disease.
  • Heydari, Hossein; Qom University of Medical Sciencies Departament Pediatrics Infectious Disease.
  • Taghi Haghi Ashtiani, Mohammad; Tehran University of Medical Sciences School of Medicine Department of pathology.
  • Mamishi, Setareh; Tehran University of Medical Sciences Pediatrics Infectious Diseases Research Center ,Tehran University of Medical Sciences School of Medicine Department of Infectious Disease.
Article em En | VETINDEX | ID: vti-444916
Biblioteca responsável: BR68.1
ABSTRACT
Emerging antimicrobial resistance rates and Extended-spectrum beta-lactamase producing Escherichia coli recovered from urinary tract infections (UTI) is an increasing problem in specific regions, limiting therapeutic options. One hundred E. coli isolates causing UTI in patients with age from 2 months to 12 years admitted at CMC in the period of April 2009 to March 2010 were tested for antibiotic susceptibility using the disk diffusion method. Surprisingly high resistance rates were recorded for E. coli against TMP/SMX (84%), cefalotin (66%), cefuroxime (50%), cefixime (50%) and ceftriaxone (45%). Antimicrobial susceptibility of E. coli isolates was followed by meropenem (98%), amikacin (95%), nitrofurantoin (91%) and gentamicin (68%). Extended spectrum beta-lactamase production, was observed in 32% of community and 42% of nosocomial isolates. The results of this study and numerous observations regarding the increasing resistance to these antibiotics, in several countries, emphasize the need for local population-specific surveillance for guiding empirical therapy for UTI in children.
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Texto completo: 1 Base de dados: VETINDEX Idioma: En Revista: Braz. J. Microbiol. Ano de publicação: 2012 Tipo de documento: Article
Texto completo: 1 Base de dados: VETINDEX Idioma: En Revista: Braz. J. Microbiol. Ano de publicação: 2012 Tipo de documento: Article