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Strategies in 'snake venomics' aiming at an integrative view of compositional, functional, and immunological characteristics of venoms
Lomonte, Bruno; Calvete, Juan J.
Afiliação
  • Lomonte, Bruno; Universidad de Costa Rica. Facultad de Microbiología. Instituto Clodomiro Picado. San José. Costa Rica
  • Calvete, Juan J; CSIC. Instituto de Biomedicina de Valencia. Structural and Functional Venomics Laboratory. Valencia. Espanha
J. Venom. Anim. Toxins incl. Trop. Dis. ; 23: e26, 2017. graf, ilus
Article em En | VETINDEX | ID: vti-33442
Biblioteca responsável: BR68.1
Localização: BR68.1
ABSTRACT
This work offers a general overview on the evolving strategies for the proteomic analysis of snake venoms, and discusses how these may be combined through diverse experimental approaches with the goal of achieving a more comprehensive knowledge on the compositional, toxic, and immunological characteristics of venoms. Some recent developments in this field are summarized, highlighting how strategies have evolved from the mere cataloguing of venom components (proteomics/venomics), to a broader exploration of their immunological (antivenomics) and functional (toxicovenomics) characteristics. Altogether, the combination of these complementary strategies is helping to build a wider, more integrative view of the life-threatening protein cocktails produced by venomous snakes, responsible for thousands of deaths every year.(AU)
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Texto completo: 1 Base de dados: VETINDEX Assunto principal: Venenos de Serpentes / Proteômica Limite: Animals Idioma: En Revista: J. Venom. Anim. Toxins incl. Trop. Dis. Ano de publicação: 2017 Tipo de documento: Article

Texto completo: 1 Base de dados: VETINDEX Assunto principal: Venenos de Serpentes / Proteômica Limite: Animals Idioma: En Revista: J. Venom. Anim. Toxins incl. Trop. Dis. Ano de publicação: 2017 Tipo de documento: Article