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Meroanencephaly in an English Pointer neonate
Silva, Luísa Mariano Cerqueira da; Gonçalves, Helena Piúma; Santos, Thaís Cozza dos; Castro, Clarissa Caetano de; Fernandes, Cristina Gevehr; Grecco, Fabiane Borelli; Varela Junior, Antonio Sergio; Corcini, Carine Dahl.
Afiliação
  • Silva, Luísa Mariano Cerqueira da; Federal University of Pelotas. Animal Pathology Department. Pelotas. Brazil
  • Gonçalves, Helena Piúma; Federal University of Pelotas. Veterinary Clinics Department. Pelotas. Brazil
  • Santos, Thaís Cozza dos; Federal University of Pelotas. Cardiology and Diagnostic Laboratory. Pelotas. Brazil
  • Castro, Clarissa Caetano de; Federal University of Pelotas. Animal Pathology Department. Pelotas. Brazil
  • Fernandes, Cristina Gevehr; Federal University of Pelotas. Animal Pathology Department. Pelotas. Brazil
  • Grecco, Fabiane Borelli; Federal University of Pelotas. Animal Pathology Department. Pelotas. Brazil
  • Varela Junior, Antonio Sergio; Federal University of Rio Grande. Institute of Biological Sciences. Rio Grande. Brazil
  • Corcini, Carine Dahl; Federal University of Pelotas. Animal Pathology Department. Pelotas. Brazil
Acta sci. vet. (Online) ; 48(suppl.1): Pub. 517, July 5, 2020. ilus
Article em En | VETINDEX | ID: vti-33235
Biblioteca responsável: BR68.1
Localização: BR68.1
ABSTRACT

Background:

Malformations are structural or functional abnormalities in the organs and structures present at birth. Theseconditions are rarely described in the newborns of dogs and can lead to their death. Meroanencephaly is a defect of theneural tube closure malformation, a type of anencephaly and results from a failure of closure of the rostral neuropore(neural crest), and consequently the development of the calvary becomes defective. This study aims to characterize theclinical-pathological aspects of neonatal meroanencephaly since brain malformations are rare in newborn dogs.Case A 2-day-old English Pointer canine was sent for a necropsy. The newborn belonged to a litter of eight puppies, andonly this one had macroscopic cranial alterations. Another puppy that died as a consequence of being trampled by thebitch was also necropsied. The newborn was alive for 48 h until death and presented apathy, crying, sucking reflex andopisthotonus. Macroscopic examination of the baby revealed flattening of the skull, with a slit at the site of bone symphysis fusion, and a slit in the skin of the parietal region, covered by thin, translucent meningeal tissue. The newborn hadno other macroscopic changes. The heads of the two animals were examined by radiography to identify the features ofanencephaly in one of the animals by visualizing skull bone flattening. Upon removing the skin and exposing the cranialcavity, an irregular reddish mass was revealed, that corresponded microscopically to area cerebrovasculosa, composed ofneurons and rudimentary glial tissue, vascular neoformation and, hemorrhage and congestion. The cranial nerves was notpossible to observe. There was disorganization of the brain areas with no limitation of white and gray matter and scarceneurons and also a region similar to the cerebellum, with a molecular layer but without the Purkinje neurons. In the spinal...(AU)
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Texto completo: 1 Base de dados: VETINDEX Assunto principal: Anormalidades Congênitas / Tubo Neural / Anencefalia / Crista Neural Limite: Animals Idioma: En Revista: Acta sci. vet. (Impr.) / Acta sci. vet. (Online) Ano de publicação: 2020 Tipo de documento: Article / Project document

Texto completo: 1 Base de dados: VETINDEX Assunto principal: Anormalidades Congênitas / Tubo Neural / Anencefalia / Crista Neural Limite: Animals Idioma: En Revista: Acta sci. vet. (Impr.) / Acta sci. vet. (Online) Ano de publicação: 2020 Tipo de documento: Article / Project document