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Improvement of bone repair in diabetic rats subjected to 780 nm low-level laser therapy
Nascimento, Marismar Fernandes do; Almeida, Bernadeth Moda de; Cunha, John Lennon Silva; Valois, Rafael Barreto Vieira; Pinheiro, Juliana Campos; Ribeiro, Maria Amália Gonzaga; Lima, Sonia Oliveira; Albuquerque-Júnior, Ricardo Luiz Cavalcanti de.
Afiliação
  • Nascimento, Marismar Fernandes do; Universidade Tiradentes. Postgraduate Program in Industrial Biotechnology. Aracaju. Brazil
  • Almeida, Bernadeth Moda de; Universidade Tiradentes. Postgraduate Program in Industrial Biotechnology. Aracaju. Brazil
  • Cunha, John Lennon Silva; Universidade Tiradentes. Aracaju. Brazil
  • Valois, Rafael Barreto Vieira; Universidade Tiradentes. Aracaju. Brazil
  • Pinheiro, Juliana Campos; Universidade Tiradentes. Aracaju. Brazil
  • Ribeiro, Maria Amália Gonzaga; Universidade Federal de Sergipe. Department of Dentistry. Aracaju. Brazil
  • Lima, Sonia Oliveira; Universidade Tiradentes. Department of Medicine. Laboratory of Morphology and Experimental Pathology. Aracaju. Brazil
  • Albuquerque-Júnior, Ricardo Luiz Cavalcanti de; Universidade Tiradentes. Department of Medicine. Laboratory of Morphology and Experimental Pathology. Aracaju. Brazil
Acta cir. bras. ; 30(10): 660-667, Oct. 2015. ilus, tab, graf
Article em En | VETINDEX | ID: vti-23335
Biblioteca responsável: BR68.1
Localização: BR68.1
ABSTRACT
To investigate the effect of low-level laser therapy on bone healing in diabetic rats.

METHODS:

Bone cavities (19 mm diameter) were performed in the femur of 72 alloxan-induced diabetic rats, which were assigned into four groups CTR (non-diabetic control), DBT (diabetic) CTRL (non-diabetic irradiated) and DBTL (diabetic irradiated). Low-level laser therapy was performed every 48h for seven days. Animals were euthanized at seven, 18 and 30 days. Alkaline phosphatase serum levels and bone repair were analyzed.

RESULTS:

Low-level laser therapy significantly increased alkaline phosphatase in at seven and 18 days (p 0.001), and improved bone healing at seven (p 0.01), 18 (p 0.05) and 30 (p 0.01) in diabetic animals. In addition, bone healing in irradiated diabetic group was statistically similar to control group at 30 days (p>0.05).

CONCLUSION:

Low-level laser therapy increased the serum levels of alkaline phosphatase and improved bone healing in alloxan-induced diabetic rats.(AU)
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Texto completo: 1 Base de dados: VETINDEX Assunto principal: Osteogênese / Diabetes Mellitus Experimental / Fosfatase Alcalina Limite: Animals Idioma: En Revista: Acta cir. bras. Ano de publicação: 2015 Tipo de documento: Article
Texto completo
Adicionar na Minha BVS
Imprimir
XML
Buscar no Google

Texto completo: 1 Base de dados: VETINDEX Assunto principal: Osteogênese / Diabetes Mellitus Experimental / Fosfatase Alcalina Limite: Animals Idioma: En Revista: Acta cir. bras. Ano de publicação: 2015 Tipo de documento: Article