Your browser doesn't support javascript.
loading
Collared Pecary (Tayassu tajacu) as a new model of renal ischemic injury induced by clamping the renal artery
Bezerra, Dayseanny de Oliveira; Feitosa, Matheus Levi Tajra; Almeida, Hatawa Melo de; Costa, Francisco Assis Lima; Braga, Juliana Fortes Vilarinho; Souza, Francisco de Assis Leite; Alves, Flávio Ribeiro; Pessoa, Gerson Tavares; Carvalho, Maria Acelina Martins de.
Afiliação
  • Bezerra, Dayseanny de Oliveira; Federal University of Piaui (UFPI). Veterinary Morphophisiology Department. Postgraduate Program in Animal Science. Teresina. Brazil
  • Feitosa, Matheus Levi Tajra; Federal University of Piaui (UFPI). Veterinary Morphophisiology Department. Postgraduate Program in Animal Science. Teresina. Brazil
  • Almeida, Hatawa Melo de; Federal University of Piaui (UFPI). Veterinary Morphophisiology Department. Postgraduate Program in Animal Science. Teresina. Brazil
  • Costa, Francisco Assis Lima; Federal University of Piaui (UFPI). Veterinary Clinical and Surgery Department. Teresina. Brazil
  • Braga, Juliana Fortes Vilarinho; Federal University of Minas Gerais (UFMG). Veterinary Patology Department. Postgraduate Program in Animal Pathology. Belo Horizonte. Brazil
  • Souza, Francisco de Assis Leite; Federal University of Piaui (UFPI). Veterinary Clinical and Surgery Department. Postgraduate Program in Animal Science. Teresina. Brazil
  • Alves, Flávio Ribeiro; Federal University of Piaui (UFPI). Veterinary Morphophisiology Department. Postgraduate Program in Animal Science. Teresina. Brazil
  • Pessoa, Gerson Tavares; Federal University of Piaui (UFPI). Veterinary Morphophisiology Department. Postgraduate Program in Animal Science. Teresina. Brazil
  • Carvalho, Maria Acelina Martins de; Federal University of Piaui (UFPI). Veterinary Morphophisiology Department. Anatomy Unit. Teresina. Brazil
Acta cir. bras. ; 29(9): 560-572, Sept. 2014. ilus, graf, tab
Article em En | VETINDEX | ID: vti-21947
Biblioteca responsável: BR68.1
Localização: BR68.1
ABSTRACT

PURPOSE:

The use of the collared peccary as an experimental model for ischemic nephropathy.

METHODS:

A total of 12 collared peccary (Tayassu tajacu) was used and ischemic nephropathy was induced in six of these animals that constituted the experimental group (G1) while the other six formed the control group (G2). Ischemic nephropathy was induced surgically by partial occlusion of the left renal artery. The disease course was assessed by hematological tests, serum chemistry, urinalysis, ultrasound (US) and doppler ultrasound function of the renal artery before induction, and at five, 10, 15 and 20 days after surgery. Twenty days after the occlusion, unilateral nephrectomy and histopathological examination were performed to assess renal morphology.

RESULTS:

Statistical analysis by Fischer's test showed a significant difference (p<0.05) between the control group and the experimental group. The histopathological examination showed glomerular, tubular and interstitial lesions. In the experimental group, 83.3% (5 /6) showed moderate renal lesions and only 16.7% (1/6) were classified with no lesions. The ultrasound examination of the right kidney presented statistical difference between day 5 and day 10 post occlusion.

CONCLUSION:

The collared peccary as a good experimental model for ischemic renal disease, because it could be manipulated during the research time without death, with health conditions that permit any subsequent procedure for disease therapy.(AU)
Assuntos
Palavras-chave
Texto completo
Adicionar na Minha BVS
Imprimir
XML
Buscar no Google

Texto completo: 1 Base de dados: VETINDEX Assunto principal: Artiodáctilos / Artéria Renal / Isquemia / Nefropatias Limite: Animals Idioma: En Revista: Acta cir. bras. Ano de publicação: 2014 Tipo de documento: Article
Texto completo
Adicionar na Minha BVS
Imprimir
XML
Buscar no Google

Texto completo: 1 Base de dados: VETINDEX Assunto principal: Artiodáctilos / Artéria Renal / Isquemia / Nefropatias Limite: Animals Idioma: En Revista: Acta cir. bras. Ano de publicação: 2014 Tipo de documento: Article