Alternative animal model for studies of total skin thickness burns
Acta cir. bras.
; 32(10): 836-842, Oct. 2017. ilus, tab
Article
em En
| VETINDEX
| ID: vti-17321
Biblioteca responsável:
BR68.1
Localização: BR68.1
ABSTRACT
Purpose:
To present an alternative experimental model of third degree burn of easy reproducibility.Methods:
Eighteen male Wister rats were randomly divided into three groups, 6 of which were allocated to each group. A soldering iron coupled to an aluminum plate was used to produce burn, at a temperature of 150ºC, with different exposure times per group. Group 5 (G5) animals were burned at 150°C with exposure time of 5 seconds; Group 10 (G10) the animals were burned at 150°C with exposure time of 10 seconds and group 15 (G15) the animals were burned at 150°C with exposure time of 15 seconds.Results:
Histopathological analyzes showed that all three groups had similar morphological characteristics, with total thickness involvement.Conclusion:
The technique is effective to reproduce a third degree burn and suggests the temperature of 150ºC with 5 seconds of exposure in order to minimize the risks to the animals.(AU)Palavras-chave
Texto completo:
1
Base de dados:
VETINDEX
Assunto principal:
Queimaduras
/
Modelos Animais
Limite:
Animals
Idioma:
En
Revista:
Acta cir. bras.
Ano de publicação:
2017
Tipo de documento:
Article