Paraganglioma de corpo aórtico em cão / Aortic body paraganglioma in dog
Acta sci. vet. (Impr.)
; 45(suppl.1): 1-4, 2017. ilus
Article
em Pt
| VETINDEX
| ID: biblio-1457775
Biblioteca responsável:
BR68.1
ABSTRACT
Background:
Aortic body paragangliomas are uncommon neoplasms that develop mainly in aortic and carotid bodies. It has been supposed that genetic factors and chronic hypoxia may stimulate tumor development. The brachycephalic dog breeds, as Boxer, are most predisposed to present this neoplasm. The clinical symptomatology is related to tumor size and localization. Usually aortic body paraganglioma has benign biological behavior, when it is malignant, rarely promotes metastases. The aim of this study was to report a case of the aortic body paraganglioma as death cause in a dog. Case A canine, 10-year-old, male, cross breed, presented clinical signs as anorexia, emesis, cough, dyspnea and exercise intolerance. After death the animal was examined at the Department of Veterinary Pathology at the Federal Rural University of Amazonia. On necropsy, no pericardial effusion was identified, however pleural and abdominal effusion was observed, volume like 1000 and 700 mL, respectively. The heart had a neoplasm near the left atrium, it measured 6.5 x 8.2 cm, had irregular surface, firm consistency, grayish color, and at the cut showed infiltration in the myocardium, as well as obstruction of the left atrial lumen and left ventricle concentric hypertrophy. No distant metastases were found. Microscopically, the tumor consisted of polyhedral morphology cells, eosinophilic cytoplasm, spherical and hyperchromatic nucleus. Cells were grouped into lobes separated by fibrovascular stroma, large cells (less uniform cells), low mitotic rate and myocardial infiltration. On immunohistochemical analysis anti-cytokeratin, anti-vimentin and anti-S-100 antibodies were used. Tumour cells stained was absent for anti-cytokeratin and anti-vimentin, but was anti-S-100 positive. A case of malignant aortic body paraganglioma grade II was diagnosed.[ ]Palavras-chave
Texto completo:
1
Base de dados:
VETINDEX
Assunto principal:
Corpos Aórticos
/
Paraganglioma Extrassuprarrenal
Limite:
Animals
Idioma:
Pt
Revista:
Acta sci. vet. (Impr.)
/
Acta sci. vet. (Online)
Ano de publicação:
2017
Tipo de documento:
Article