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Incidence of penile cancer worldwide: systematic review and meta-analysis
Article em En | PAHOIRIS | ID: phr-34438
Biblioteca responsável: US1.1
ABSTRACT
Objective. To determine the global incidence of penile cancer. Methods. A systematic review and meta-analysis of observational studies was performed, with no limits on their language of publication. Analyses were performed using Stata 13 statistical software. A random-effects model was used, according to the heterogeneity found in the studies. The main outcome was expressed in terms of age-standardized incidence. Results. A total of 23 studies were eligible, with 71 156 penile cancer patients in 86 countries. According to the review conducted, the estimated age-standardized incidence of penile cancer worldwide is 0.84 cases per 100 000 person-years (95% confidence interval 0.79–0.89). Romania reported the highest incidence, 7.26 per 100 000 person-years, between 1983 and 1987; however, some countries in Latin America and Africa reported an incidence of between 2.0 and 5.7 per 100 000. Conclusions. Penile cancer is considered a rare malignancy due to its already-known, particularly low incidence rate. The estimated age-standardized incidence rate by the world standard population today is 0.84 cases per 100 000 person-years. There were no significant differences in the incidence rate of penile cancer with respect to the distribution by continent or the trend over time.
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Texto completo: 1 Coleções: 04-international_org Base de dados: PAHOIRIS Assunto principal: Neoplasias Penianas / Incidência / Estudos Observacionais como Assunto Tipo de estudo: Clinical_trials / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Idioma: En Ano de publicação: 2017 Tipo de documento: Article
Texto completo: 1 Coleções: 04-international_org Base de dados: PAHOIRIS Assunto principal: Neoplasias Penianas / Incidência / Estudos Observacionais como Assunto Tipo de estudo: Clinical_trials / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Idioma: En Ano de publicação: 2017 Tipo de documento: Article