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Nitric oxide levels in children with febrile illnesses - Poster abstract
Bissoon, D; Ramchandani, N; Monteil, Michele A; Carrington, C. V. F.
Afiliação
  • Bissoon, D; University of the West Indies, St. Augustine, Trinidad and Tobago. Faculty of Medical Sciences
  • Ramchandani, N; University of the West Indies. Faculty of Medical Sciences
  • Monteil, Michele A; University of the West Indies, St. Augustine, Trinidad and Tobago. Faculty of Medical Sciences
  • Carrington, C. V. F; University of the West Indies, St. Augustine, Trinidad and Tobago. Faculty of Medical Sciences
West Indian med. j ; 49(suppl. 2): 60-1, Apr. 2000.
Article em En | MedCarib | ID: med-885
Biblioteca responsável: JM3.1
Localização: JM3.1; R18.W4
ABSTRACT

OBJECTIVE:

To determine nitric oxide (NO) levels in children with febrile illness and to investigate its prognostic value in early dengue virus infections. DESIGN AND

METHOD:

A pilot case control study was conducted from September 1998 to March 1999 at the Eric Williams Medical Sciences Complex, Priority Care Facility (PCF), in Trinidad. Serum NO concentrations were measured in children <12 years presenting with febrile illnesses in the absence of clinically significant bacterial infection.

RESULTS:

Of 59 blood samples collected, there were 22 from individuals diagnoses as virally induced gastroenteritis (VGE), with 31 non-specific viral illnesses (VI), and 6 viral infections associated with upper-respiratory tract infection (URTI-VI). The mean (NO) in all cases was above normal (11.9 uM SD 5.9) 81.17 uM in VGE, 41.30 uM in VI and 57.83 uM in URTI-VI. Krushkal-Wallis test revealed that there was a significant difference (p = 0.007) between all three means and that the mean (NO) for VGE was significantly higher (p = 0.003) than that of VI.

CONCLUSIONS:

The degree of elevation of NO varies between viral illnesses in children and its potential as a rapid prognostic marker warrants further investigation.(AU)
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Coleções: 01-internacional Base de dados: MedCarib Assunto principal: Dengue / Febre / Óxido Nítrico Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Child / Humans País/Região como assunto: Caribe ingles / Trinidad y tobago Idioma: En Revista: West Indian med. j Ano de publicação: 2000 Tipo de documento: Article
Buscar no Google
Adicionar na Minha BVS
Imprimir
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Coleções: 01-internacional Base de dados: MedCarib Assunto principal: Dengue / Febre / Óxido Nítrico Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Child / Humans País/Região como assunto: Caribe ingles / Trinidad y tobago Idioma: En Revista: West Indian med. j Ano de publicação: 2000 Tipo de documento: Article