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Autoimmune haemolytic anaemia, immune thrombocytopenia, and leucopenia - an unusual presentation of hodgkin's disease
West Indian med. j ; 46(3): 95-6, Sept. 1997.
Article em En | MedCarib | ID: med-1982
Biblioteca responsável: JM3.1
Localização: JM3.1; R18.W4
ABSTRACT
We report an unusual case of modular sclerosing Hodgkin's disease in a 17 year old women presenting with intermittent fever, progressive weight loss and enlarged cervical and anxillary lymp nodes. Laboratory test revealed severe Coombs' positive haemolytic anaemia, and progressive thrombocytopenia and leucopenia, associated with erythroid, myeloid and megakaryocytic hyperplasia, but with no evidence of lymphomatous infiltration in the bone marrow. Transfusion of compatible blood became possible only after prednisone therapy and a single intravenous dose of vincristine. Appropriate chemotherapy led to normalization of the peripheral blood counts and a negative direct Coombs' test.(AU)
Assuntos
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Coleções: 01-internacional Base de dados: MedCarib Assunto principal: Trombocitopenia / Doença de Hodgkin / Anemia Hemolítica Autoimune Limite: Adolescent / Female / Humans Idioma: En Revista: West Indian med. j Ano de publicação: 1997 Tipo de documento: Article
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Coleções: 01-internacional Base de dados: MedCarib Assunto principal: Trombocitopenia / Doença de Hodgkin / Anemia Hemolítica Autoimune Limite: Adolescent / Female / Humans Idioma: En Revista: West Indian med. j Ano de publicação: 1997 Tipo de documento: Article