Comorbid disease in asthma: the importance of diagnosis
Expert review of respiratory medicine
; 4(3): 271-274, Jun. 2010.
Article
em En
| MedCarib
| ID: med-17689
Biblioteca responsável:
TT5
ABSTRACT
William Osler's comprehensive definition of bronchial asthma as "a neurotic affection characterized by hyperemia and turgescence of the mucosa of the smaller bronchial tubes
a peculiar exudate of mucin attacks
due to direct irritation of the bronchial mucosa or induced reflexly, by irritation of the nasal mucosa, and indirectly by reflex influences from stomach, intestines or genital organs" has been chiseled away to a chronic inflammatory disorder of the airways [1]. Asthmas sharp climb in developing countries parallels their growing urbanization and westernization, eclipsing its rising prevalence in developed nations. Disease morbidity and mortality is higher in low- and lowermiddle-income countries [101] particularly among the elderly, where atypical presentations and comorbidities render it likely to be underdiagnosed [2]. Common comorbidities associated with frequent exacerbations in difficult-to-treat asthma include hiatus hernia with or without associated gastroesophageal reflux disease (GERD), rhinosinusitis, recurrent respiratory infections, psychological disturbances and obstructive sleep apnea (OSA) [3,4]. Undiagnosed comorbid disease influences diagnosis, treatment response, disease management and control of asthma.
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MedCarib
Assunto principal:
Doenças Respiratórias
/
Asma
/
Trinidad e Tobago
/
Comorbidade
/
Diabetes Mellitus
/
Obesidade
Tipo de estudo:
Diagnostic_studies
/
Risk_factors_studies
Limite:
Adolescent
/
Adult
/
Aged
/
Aged80
/
Child
/
Child, preschool
/
Female
/
Humans
/
Infant
/
Male
País/Região como assunto:
Caribe ingles
/
Trinidad y tobago
Idioma:
En
Revista:
Expert review of respiratory medicine
Ano de publicação:
2010
Tipo de documento:
Article