Distribution of coronary and aortic atherosclerosis by geographic location, race, and sex
Lab Invest
; 18(5): 509-26, May 1968.
Article
em En
| MedCarib
| ID: med-12428
Biblioteca responsável:
JM3.1
Localização: JM3.1; RB37.A1L3
ABSTRACT
Cooperating pathologists in different countries collected 23,207 sets of coronary arteries and aortae, according to a standard protocol. A central laboratry staff stained the arteries with Sudan IV, and a team of pathologists graded the atherosclerotic lesions. A basal group of cases which died from accidents, infections, cancer, and selected miscellaneous causes was extracted in order to compare atherosclerosis among the different geographic, racial, and sex subgroups. Even the most homogeneous subgroups (same location, sex, age, and race) vary greatly in extent of advanced atherosclerotic lesions. The 19 location-race groups differ significantly in extent of raised lesions. The abdominal aorta and the left anterior descending coronary artery have more atherosclerosis than other arteries. Within most location-race groups, coronary arteries of men have more raised lesions than the coronary arteries of women. Aortae of men in some groups have slightly more, and in other groups slightly less raised lesions than the aortae of women. Negro groups show little or no sex difference in either the coronary arteries or the aorta. Ranking of the 19 location-race groups by raised atherosclerotic lesions is similar, regardless of lesion measure (fatty streaks excepted), sex, artery, or age group. New Orleans white and the Oslo group rank highest; Bogota, Sao Paulo Negro, Guatemala, and Durban Bantu groups rank lowest. With few exceptions, ranking these groups by raised lesions corresponds closely with ranking them by coronary heart disease mortality rate. (AU)
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Coleções:
01-internacional
Base de dados:
MedCarib
Assunto principal:
Arteriosclerose
/
Doença das Coronárias
Aspecto:
Determinantes_sociais_saude
Limite:
Adolescent
/
Adult
/
Female
/
Humans
/
Male
País/Região como assunto:
Africa
/
America central
/
America do sul
/
Asia
/
Caribe
/
Caribe ingles
/
Europa
/
Guatemala
/
Jamaica
/
Mexico
Idioma:
En
Revista:
Lab Invest
Ano de publicação:
1968
Tipo de documento:
Article