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The short-term prognosis of severe primary infantile malnutrition
Br J Nutr ; 21: 155-65, 1967.
Article em En | MedCarib | ID: med-12140
Biblioteca responsável: JM3.1
Localização: JM3.1; Reprint Collection
ABSTRACT
Among a series of 343 children with severe primary malnutrition there were 248 for whom, on admission, there were reliable records of age, weight, height, liver size, severity of oedema, skin lesions and angular stomatitis, and concentration of total serum protein, haemoglobin and sodium. For eighty-four of these children the serum bilirium concentration was also known. The correlations of these characteristics of the children on admission, with mortality, and with the rate of recovery were investigated. Age, weight, oedema and haemoglobin concentration were not significantly related to mortality or to rate of recovery. A multiple regression analysis showed that an increased serum bilirubin concentration and a decreased serum sodium concentration indicated a bad prognosis, and these two factors contributed almost the whole of the multiple correlation coefficient of 0.63 with respect to mortality and 0.59 with respect to speed of recovery. We conclude that in our series of children death was more closely associated with liver failure or overhydration than with protein depletion, and suggest that the administration of too much protein or water to an acutely ill malnourished child may precipitate death. This analysis shows that the mortality observed in our series cannot be adequately explained by any combination of the characteristics considered above; there must, therefore, be other factors of importance for which we do not have suitable measurements. (AU)
Assuntos
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Coleções: 01-internacional Base de dados: MedCarib Assunto principal: Transtornos da Nutrição do Lactente Tipo de estudo: Prognostic_studies Limite: Child, preschool / Humans / Infant Idioma: En Revista: Br J Nutr Ano de publicação: 1967 Tipo de documento: Article
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Coleções: 01-internacional Base de dados: MedCarib Assunto principal: Transtornos da Nutrição do Lactente Tipo de estudo: Prognostic_studies Limite: Child, preschool / Humans / Infant Idioma: En Revista: Br J Nutr Ano de publicação: 1967 Tipo de documento: Article