Aminoglycoside resistance in clinical isolates of gram-negative bacilli at the University Hospital of the West Indies
West Indian med. j
; 32(3): 130-9, Sept. 1983.
Article
em En
| MedCarib
| ID: med-11428
Biblioteca responsável:
JM3.1
Localização: JM3.1; R18.W4
ABSTRACT
The pattern of aminoglycoside resistance in clinical isolates of gram-negative bacilli at the University Hospital of the West Indies, Jamaica, was studied. The levels of resistance were (1) kanamycin 50.4 percent, (2) gentamicin 6.7 percent, (3) tobramycin 5.9 percent and (4) amikacin 0.6 percent. There was considerable cross-resistance between gentamicin and tobramycin among strains of enterobacteriaceae. Tobramycin, however, was superior to gentamicin against isolates of Pseudomonas. Amikacin was the most active aminoglycoside and was effective against 99.4 percent of all isolates tested. Furthermore, it was effective against isolates resistant to one or more of the other amino-glycosides. Measures to prevent further increase in aminoglycoside resistance, especially in the judicious usage of these valuable agents and strict adherence to the principles of cross-infection control while dealing with patients infected or colonized with resistant strains, are discussed and emphasized (AU)
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Coleções:
01-internacional
Base de dados:
MedCarib
Assunto principal:
Bactérias
/
Antibacterianos
País/Região como assunto:
Caribe
/
Caribe ingles
/
Jamaica
Idioma:
En
Revista:
West Indian med. j
Ano de publicação:
1983
Tipo de documento:
Article