Fatal enterovirus 71 encephalomyelitis.

Lum, L C; Wong, K T; Lam, S K; Chua, K B; Goh, A Y; Lim, W L; Ong, B B; Paul, G; AbuBakar, S; Lambert, M

Lum, L C; Wong, K T; Lam, S K; Chua, K B; Goh, A Y; Lim, W L; Ong, B B; Paul, G; AbuBakar, S; Lambert, M.

Afiliação

Lum LC; Department of Pediatrics, the Department of Pathology, the Department of Medical Microbiology, Faculty of Medicine, University of Malaya, Kuala Lumpur, Malaysia.

J Pediatr ; 133(6): 795-8, 1998 Dec.

Article em En | MEDLINE | ID: mdl-9842048

RESUMO

During an outbreak of hand-foot-mouth disease caused by enterovirus 71 (EV-71) in 1997, 4 children presented with sudden cardiopulmonary collapse and minimal neurologic features. All children received cardiopulmonary resuscitation but died within a few hours of admission. Postmortem studies showed infection by EV-71 with extensive damage to the medulla and pons. We postulate an etiologic link between EV-71 and brainstem encephalomyelitis as the cause of pulmonary edema and death.

Assuntos

Encefalomielite/virologia; Infecções por Enterovirus; Pré-Escolar; Encefalomielite/patologia; Infecções por Enterovirus/patologia; Evolução Fatal; Feminino; Humanos; Lactente; Masculino; Bulbo/patologia; Edema Pulmonar/virologia

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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encefalomielite / Infecções por Enterovirus Limite: Child, preschool / Female / Humans / Infant / Male Idioma: En Revista: J Pediatr Ano de publicação: 1998 Tipo de documento: Article País de afiliação: Malásia País de publicação: Estados Unidos

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