An in vivo model to study the anti-malaric capacity of plant extracts.
Rev Biol Trop
; 46(1): 35-9, 1998 Mar.
Article
em En
| MEDLINE
| ID: mdl-9711350
An in vivo model to study the antimalaric effect of plant extracts is described. White mice (25-30 g body weight) are treated subcutaneously with 0.6 ml of the diluted extract starting seven days before P. berghei infection; treatment continues until death or for 30 days. Simultaneously 0.2 ml of the extract are applied per os starting three days before infection. In a test of the model, treated and non-treated animals differed in body weight, survival time, haematocrite, parasitemia development, and spleen or liver weight of recent dead or killed mice.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Plasmodium berghei
/
Extratos Vegetais
/
Malária
/
Antimaláricos
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
En
Revista:
Rev Biol Trop
Ano de publicação:
1998
Tipo de documento:
Article
País de afiliação:
Costa Rica
País de publicação:
Costa Rica