[Treatment of diabetic neuropathy]. / Tratamiento de la neuropatía diabética.
Gac Med Mex
; 134(1): 85-92, 1998.
Article
em Es
| MEDLINE
| ID: mdl-9658700
Diabetic polyneuropathy is a complication, that affects most patients with longstanding diabetes mellitus, deteriorating their quality of life. In the last few years, new therapeutic approaches have been developed that can improve symptoms and neurologic function, and which may prevent and in some cases stop nerve damage, and even, promote nerve fiber regeneration. These treatments are supported by several investigations in animals and humans: a) thigh glycemic control (insulin), b) aldose reductase inhibition (tolrestat), c) prevention of protein glycation (amino-guanidine), d) improvement of nerve ischemia (vaso-dilators, gamma-linolenic acid), and e) administration of neurotrophic factors (gangliosides). Most evidence support the usefulness for glycemic control. Early treatment is suggested, because marked nerve fiber loss is present in advanced neuropathy.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neuropatias Diabéticas
Aspecto:
Patient_preference
Limite:
Animals
/
Humans
Idioma:
Es
Revista:
Gac Med Mex
Ano de publicação:
1998
Tipo de documento:
Article
País de publicação:
México