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Spirulina maxima prevents induction of fatty liver by carbon tetrachloride in the rat.
Torres-Durán, P V; Miranda-Zamora, R; Paredes-Carbajal, M C; Mascher, D; Díaz-Zagoya, J C; Juárez-Oropeza, M A.
Afiliação
  • Torres-Durán PV; Departamento de Bioquímica, UNAM, México, D.F., Mexico.
Biochem Mol Biol Int ; 44(4): 787-93, 1998 Apr.
Article em En | MEDLINE | ID: mdl-9584992
The aim of the present work was to assess the capacity of Spirulina maxima to prevent fatty liver development induced in rats by an intraperitoneal single dose (1 ml/kg) of carbon tetrachloride. Liver and serum lipids were quantified two or four days after treatment with this agent. Liver lipid concentration did not differ in rats fed on a purified diet with or without Spirulina. However, after carbon tetrachloride treatment, liver triacylglycerols were significantly lower in rats fed on a diet with Spirulina 5% than in rats without Spirulina in their diet (P < 0.05). Furthermore, the increased liver cholesterol values, induced by carbon tetrachloride treatment, were not observed in rats that received Spirulina. These results support the potential hepatoprotective role of Spirulina.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cianobactérias / Fígado Gorduroso Limite: Animals Idioma: En Revista: Biochem Mol Biol Int Assunto da revista: BIOLOGIA MOLECULAR / BIOQUIMICA Ano de publicação: 1998 Tipo de documento: Article País de afiliação: México País de publicação: Reino Unido
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Cianobactérias / Fígado Gorduroso Limite: Animals Idioma: En Revista: Biochem Mol Biol Int Assunto da revista: BIOLOGIA MOLECULAR / BIOQUIMICA Ano de publicação: 1998 Tipo de documento: Article País de afiliação: México País de publicação: Reino Unido