Rotavirus and reovirus interaction with mouse peritoneal resident phagocytic cells.
Braz J Med Biol Res
; 30(10): 1187-90, 1997 Oct.
Article
em En
| MEDLINE
| ID: mdl-9496436
Rotaviruses and reoviruses are involved in human and animal diseases. It is known that both viruses penetrate the gastrointestinal tract but their interaction with phagocytic cells is unknown. To study this interaction, peritoneal resident phagocytic cells were used and rotavirus and reovirus replication in peritoneal phagocytic cells was observed. However, rotavirus replication in these cells led to the production of defective particles since MA-104 cells inoculated with rotavirus phagocytic cell lysate did not show any evidence of virus replication. On the basis of these results, we suggest that, although reovirus dissemination may be helped by these phagocytic cells, these cells may control rotavirus infection and probably contribute to the prevention of its dissemination.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Peritônio
/
Fagócitos
/
Reoviridae
/
Rotavirus
Limite:
Animals
Idioma:
En
Revista:
Braz J Med Biol Res
Ano de publicação:
1997
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Brasil