Seroreactivity to HIV-1 V3 subtypes A to H peptides of Argentinian HIV-positive sera.
J Acquir Immune Defic Syndr Hum Retrovirol
; 17(2): 156-9, 1998 Feb 01.
Article
em En
| MEDLINE
| ID: mdl-9473017
ABSTRACT
PIP: 175 serum samples were collected from 175 HIV-infected Argentineans in Buenos Aires and Rosario during 1987-95, for testing against a panel of peptides representing V3 consensus HIV-1 subtypes A through H. A V3 peptide enzyme immunoassay was used to screen the sera. 58.28% of the sera were infected with HIV-1 subtype B, 13.14% with subtype F, 8.57% with subtype A, 4% with subtype H, 2.85% with subtype D, 2.28% with subtype G, and 1.71% with subtype C. Some cross-reactivity between peptides was observed. Peripheral blood mononuclear cells (PBMCs) were obtained from 8 HIV-infected subjects from Rosario for use in determining genotypes. 7 of the 8 genotyped patients reacted with their respective consensus B peptide and 1 reacted with consensus B and F. V3 peptide serology proved useful in determining which HIV-1 clades are circulating in Argentina.
Palavras-chave
Acquired Immunodeficiency Syndrome; Americas; Argentina; Demographic Factors; Developing Countries; Diseases; Examinations And Diagnoses; Hiv; Hiv Infections; Hiv Serodiagnosis; Laboratory Examinations And Diagnoses; Latin America; Measurement; Population; Population Characteristics; Prevalence; Research Methodology; Research Report; South America; Urban Population; Viral Diseases
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fragmentos de Peptídeos
/
Anticorpos Anti-HIV
/
Proteína gp120 do Envelope de HIV
/
HIV-1
/
Soropositividade para HIV
Limite:
Humans
País/Região como assunto:
America do sul
/
Argentina
Idioma:
En
Revista:
J Acquir Immune Defic Syndr Hum Retrovirol
Assunto da revista:
SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS)
/
VIROLOGIA
Ano de publicação:
1998
Tipo de documento:
Article
País de afiliação:
Argentina
País de publicação:
Estados Unidos