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Bacillus thuringiensis: from biodiversity to biotechnology.
Prieto-Samsónov, D L; Vázquez-Padrón, R I; Ayra-Pardo, C; González-Cabrera, J; de la Riva, G A.
Afiliação
  • Prieto-Samsónov DL; Laboratory of Environmental Biotechnology, Centre for Genetic Engineering and Biotechnology (CIGB), Havana, Cuba.
J Ind Microbiol Biotechnol ; 19(3): 202-19, 1997 Sep.
Article em En | MEDLINE | ID: mdl-9418060
Bacillus thuringiensis is a Gram-positive bacterium, widely used in agriculture as a biological pesticide. The biocidal activity mainly resides in a parasporal protein inclusion body, or crystal. The inclusion is composed of one or more types of delta-endotoxins (Cry and Cyt proteins). Cry proteins are selectively toxic to different species from several invertebrate phyla: arthropods (mainly insects), nematodes, flatworms and protozoa. The mode of action of the insecticidal proteins is still a matter of investigation; generally, the active toxin is supposed to bind specific membrane receptors on the insect midgut brush-border epithelium, leading to intestinal cell lysis and subsequent insect death by starvation or septicemia. The toxin-encoding cry genes have been extensively studied and expressed in a large number of prokaryotic and eukaryotic organisms. The expression of such genes in transgenic plants has provided a powerful alternative for crop protection.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bacillus thuringiensis / Proteínas de Bactérias / Toxinas Bacterianas / Proteínas Recombinantes / Controle Biológico de Vetores / Endotoxinas Idioma: En Revista: J Ind Microbiol Biotechnol Assunto da revista: BIOTECNOLOGIA / MICROBIOLOGIA Ano de publicação: 1997 Tipo de documento: Article País de afiliação: Cuba País de publicação: Alemanha
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Bacillus thuringiensis / Proteínas de Bactérias / Toxinas Bacterianas / Proteínas Recombinantes / Controle Biológico de Vetores / Endotoxinas Idioma: En Revista: J Ind Microbiol Biotechnol Assunto da revista: BIOTECNOLOGIA / MICROBIOLOGIA Ano de publicação: 1997 Tipo de documento: Article País de afiliação: Cuba País de publicação: Alemanha