[Infection with HTLV virus type I-II in patients with cervico-uterine cancer in the Yucatan peninsula, Mexico]. / Infección por virus linfotrópico de células T humanas tipo I/II en pacientes con cáncer cervicouterino de la península de Yucatán, México.
Ginecol Obstet Mex
; 65: 141-4, 1997 Apr.
Article
em Es
| MEDLINE
| ID: mdl-9280739
Southwestern Japan is an endemic zone with high prevalence of HTLV-I infection. In addition, a relation between cancer of the cervix and this retrovirus has been described. A recent study has demonstrated a low prevalence of HTLV-I/II infection in Yucatan, Mexico. However, cancer of the cervix is the most frequent oncological disease in this region. The objective of this study was to determine the relationship between cancer of the cervix and the HTLV-I/II infection. Sera from 123 patients with cancer of the cervix and 662 healthy women were screened for antibodies against HTLV-I/II by ELISA and agglutination test (PA). Results were confirmed by Western blot (WB). In the confirmed cases the differentiation between HTLV-I and HTLV-II was made by synthetic peptides. Only one woman (0.8%) had positive results in the patients group and two women (0.3%) had reactivity in the control group. In all these cases the antibodies were positive for HTLV-II. The prevalence in the group of patients with cancer of the cervix was similar to that of the control group. We therefore concluded that in Yucatan, Mexico there is no relation between HTLV-I/II infection and cancer of the cervix.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Neoplasias Uterinas
/
Leucemia-Linfoma de Células T do Adulto
/
Leucemia de Células T
/
Neoplasias do Colo do Útero
Tipo de estudo:
Risk_factors_studies
Limite:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Middle aged
País/Região como assunto:
Mexico
Idioma:
Es
Revista:
Ginecol Obstet Mex
Ano de publicação:
1997
Tipo de documento:
Article
País de publicação:
México