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[Microsurgical pancreatoduodenal transplantation in rats. Technique and results following 12 years of investigation]. / Transplante pancreatoduodenal em ratos com microcirurgia. A técnica e os resultados após 12 anos de experimentação.
Spadella, C T; Mercadante, M C; Machado, J L; Schellini, S A; de Macedo, A R.
Afiliação
  • Spadella CT; Departamento de Cirurgia e Ortopedia, FMB-UNESP.
Arq Gastroenterol ; 33(3): 158-66, 1996.
Article em Pt | MEDLINE | ID: mdl-9201329
In this study we present the technical details, adaptations and modifications of the original procedure of pancreaticoduodenal transplantation in rats described by Lee et al. in 1972. We also present the results and technical failures observed in a follow-up of 12 years. From March, 1982 to December, 1994, we performed in the Laboratory of Surgical Technique and Experimental Surgery of Faculty of Medicine, Botucatu-UNESP, Brazil, 665 duodenopancreatectomies in donor rats and 592 surgeries for revascularization of the pancreatic graft in recipient animals. The observed percentage of technical failures in donor rats was 11% due to bleeding and/or vascular complications, irregular flushing of the graft with saline and respiratory insufficiency. In recipients of grafts, we observed a percentage of technical failures of 22.5% due to porto-caval thrombosis, vascular bleeding, pancreatitis and graft ischemia. In both surgeries, the successful results are directly related to the technical performance of the surgeon and the cares in the postoperative period.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transplante de Pâncreas / Diabetes Mellitus Experimental / Duodeno Tipo de estudo: Observational_studies / Prognostic_studies Limite: Animals / Female / Humans Idioma: Pt Revista: Arq Gastroenterol Ano de publicação: 1996 Tipo de documento: Article País de publicação: Brasil
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transplante de Pâncreas / Diabetes Mellitus Experimental / Duodeno Tipo de estudo: Observational_studies / Prognostic_studies Limite: Animals / Female / Humans Idioma: Pt Revista: Arq Gastroenterol Ano de publicação: 1996 Tipo de documento: Article País de publicação: Brasil