[Histoplasmosis in immunodepressed patients: study of 18 cases seen in Uberlândia, MG]. / Histoplasmose em pacientes imunodeprimidos: estudo de 18 casos observados em Uberlândia, MG.
Rev Soc Bras Med Trop
; 30(2): 119-24, 1997.
Article
em Pt
| MEDLINE
| ID: mdl-9148334
The diagnosis of histoplasmosis was made by isolation of Histoplasma capsulatum from cerebrospinal fluid (CSF), blood and bone marrow or by histopathologic (biopsy or post mortem) examination. The mean age of the patients was 35.8 years; 13 patients were male (72.2%). The disease was disseminated, with the following distribution:skin (38.8%), bone marrow (27.7%), nasopharyngeal mucosa (22.2%), lungs (22.2%), colon (11.1%), central nervous system (5.5%) and esophagus (5.5%). Adenomegaly (50%), hepatomegaly (77.7%) and splenomegaly (61.1%) were frequently seen. The most common hematologic abnormality was pancytopenia (33.3%) of the patients. Eleven patients were treated, 9 with amphotericin B and 2 with itraconazole. Eight had good clinical improvement and all of them were given amphotericin B or a triazolic as maintenance therapy. This study emphasize the importance of this mycosis in immunodepressed patients, specially AIDS patients, in whom the infection tends to invade the macrophagic-lymphoid system and preferentially the cutaneous tegument.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Hospedeiro Imunocomprometido
/
Infecções Oportunistas Relacionadas com a AIDS
/
Histoplasmose
/
Cirrose Hepática Alcoólica
Limite:
Adult
/
Female
/
Humans
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Male
/
Middle aged
Idioma:
Pt
Revista:
Rev Soc Bras Med Trop
Ano de publicação:
1997
Tipo de documento:
Article
País de afiliação:
Brasil
País de publicação:
Brasil