[Determination of 25-hydroxyvitamin D serum levels and its seasonal variations in healthy young people]. / Determinación de los niveles séricos de 25-hidroxivitamina D y sus variaciones estacionales en una población normal joven.
Rev Med Chil
; 124(6): 675-9, 1996 Jun.
Article
em Es
| MEDLINE
| ID: mdl-9041723
BACKGROUND: 25-hydroxyvitamin D has a longer half life and its serum levels have less daily variations than calcitriol. Thus, its measurement is a better indicator of vitamin D status. AIM: To measure 25-hydroxyvitamin D levels in normal subjects during summer and winter. PATIENTS AND METHODS: Vitamin D was measured using a competitive protein binding radioassay in 61 subjects (27 male) aged 21 to 57 years old, during July and August (winter) and February and March of the next year (summer). RESULTS: 25-hydroxyvitamin levels were 28.8 +/- 1.5 and 30.9 +/- 2.3 ng/ml during winter and summer respectively. No differences were found between men and women. Ninety five percent confidence levels were between 13 and 50 ng/ml. Levels in one patient with malabsorption were 9.3 ng/ml, in 2 patients with hypophosphatemic osteomalacia were 2.1 and 9.3 ng/ml, in 12 patients with alcoholic cirrhosis were 16.4 +/- 1.3 ng/ml, in 4 patients with primary osteoporosis were 23.3 +/- 0.7 and in three patients receiving vitamin D were 334 +/- 33.2 ng/ml. CONCLUSIONS: Normal levels of 25-hydroxyvitamin D range from 13 to 50 ng/ml in normal adults, there are no differences between men and women and seasonal variations are minimal.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Estações do Ano
/
Hidroxicolecalciferóis
Limite:
Adult
/
Female
/
Humans
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Male
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Middle aged
Idioma:
Es
Revista:
Rev Med Chil
Ano de publicação:
1996
Tipo de documento:
Article
País de publicação:
Chile