The homogeneous effect of calcium ionophore A23187 on potassium loss in human foetal red cell populations.
Physiol Res
; 44(5): 275-80, 1995.
Article
em En
| MEDLINE
| ID: mdl-8869260
A "pulse like" increase of cytoplasmic calcium concentration, which is proportional to ionophore concentration, is induced in red cells by exposure to A23187. Different Ca2+ levels are attained depending on cellular calcium buffering power and/or primary active calcium transport activation. We examined the effect of A23187 concentration of potassium loss in neonatal (nRC) as well as in adult red cells (aRC). The increase in ionophore concentration produced an "all- or -none" recruitment in adult cells and a "gradual" one in neonatal red cells. The "gradual" response observed in nRC would suggest that the "all or none" character of the response is not present in red cells during the foetal stages of haematopoiesis.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Potássio
/
Calcimicina
/
Eritrócitos
/
Sangue Fetal
Limite:
Adult
/
Humans
Idioma:
En
Revista:
Physiol Res
Assunto da revista:
FISIOLOGIA
Ano de publicação:
1995
Tipo de documento:
Article
País de afiliação:
Argentina
País de publicação:
República Tcheca