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Effects of a history of heavy alcohol consumption on Alzheimer's disease.
Rosen, J; Colantonio, A; Becker, J T; Lopez, O L; DeKosky, S T; Moss, H B.
Afiliação
  • Rosen J; Department of Psychiatry, Alzheimer's Disease Research Center, University of Pittsburgh, PA.
Br J Psychiatry ; 163: 358-63, 1993 Sep.
Article em En | MEDLINE | ID: mdl-8401966
Neuropsychological and psychiatric evaluations were made of 39 subjects with possible Alzheimer's disease and a history of excessive alcohol consumption (AD + ETOH), who had been abstinent or had drunk minimally for at least three months before evaluation, and 225 patients with probable Alzheimer's disease (PAD) of comparable age, years of education, and baseline global impairment. At baseline, there were no significant differences between the groups in terms of age of onset of dementia, neuropsychological test scores, or current behavioural or psychiatric symptoms. One year later, no differences in rates of decline between 20 abstinent AD + ETOH patients and 88 PAD subjects could be shown. Thus, past heavy alcohol consumption does not appear to modify the presentation of dementia of the Alzheimer's type, nor does it modify progression over a one-year interval.
Assuntos
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Alcoolismo / Doença de Alzheimer / Testes Neuropsicológicos Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male Idioma: En Revista: Br J Psychiatry Ano de publicação: 1993 Tipo de documento: Article País de publicação: Reino Unido
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Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Alcoolismo / Doença de Alzheimer / Testes Neuropsicológicos Tipo de estudo: Diagnostic_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male Idioma: En Revista: Br J Psychiatry Ano de publicação: 1993 Tipo de documento: Article País de publicação: Reino Unido