Menopause without symptoms: the endocrinology of menopause among rural Mayan Indians.
Am J Obstet Gynecol
; 168(6 Pt 1): 1839-43; discussion 1843-5, 1993 Jun.
Article
em En
| MEDLINE
| ID: mdl-8317530
OBJECTIVE: Our purpose was to determine the characteristics of menopause among Mayan women who did not have menopausal symptoms. STUDY DESIGN: A cross-sectional study of Mayan women from Chichimila, Mexico, was performed. Demographic information, history and physical examination, hormone concentrations, and radial bone density measurement were obtained. RESULTS: Fifty-two postmenopausal women were compared with 26 premenopausal women. Menopause occurred at 44.3 +/- 4.4 years. None of the women admitted to hot flushes and did not recall significant menopausal symptoms. Hormone levels included elevated follicle-stimulating hormone (66.6 +/- 29 mlU/ml), low estradiol and estrone (9.4 +/- 8.3 and 13.3 +/- 7.8 pg/ml), estrone greater than estradiol levels, normal levels of testosterone and androstenedione (0.17 +/- 0.14 and 0.31 +/- 0.17 ng/ml). Bone mineral density declined with age, but height did not. Clinical evidence of osteoporosis was not detected. CONCLUSIONS: Lack of symptoms during the menopausal transition is not attributable to a difference in endocrinology. Postmenopausal Mayan women are estrogen deprived and experience age-related bone demineralization but do not have a high incidence of osteoporotic fractures.
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Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Menopausa
/
Indígenas Norte-Americanos
/
Glândulas Endócrinas
Tipo de estudo:
Diagnostic_studies
/
Observational_studies
/
Risk_factors_studies
Limite:
Adult
/
Female
/
Humans
/
Middle aged
País/Região como assunto:
Mexico
Idioma:
En
Revista:
Am J Obstet Gynecol
Ano de publicação:
1993
Tipo de documento:
Article
País de publicação:
Estados Unidos